NO20005155D0 - Forbedring av antistoff-cytokin fusjonsprotein medierte immunresponser ved ko-administrering med angiogenese inhibitor - Google Patents

Forbedring av antistoff-cytokin fusjonsprotein medierte immunresponser ved ko-administrering med angiogenese inhibitor

Info

Publication number
NO20005155D0
NO20005155D0 NO20005155A NO20005155A NO20005155D0 NO 20005155 D0 NO20005155 D0 NO 20005155D0 NO 20005155 A NO20005155 A NO 20005155A NO 20005155 A NO20005155 A NO 20005155A NO 20005155 D0 NO20005155 D0 NO 20005155D0
Authority
NO
Norway
Prior art keywords
angiogenesis inhibitor
antibody
enhancement
administration
fusion protein
Prior art date
Application number
NO20005155A
Other languages
English (en)
Other versions
NO20005155L (no
Inventor
Stephen D Gillies
Original Assignee
Lexigen Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexigen Pharm Corp filed Critical Lexigen Pharm Corp
Publication of NO20005155D0 publication Critical patent/NO20005155D0/no
Publication of NO20005155L publication Critical patent/NO20005155L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20005155A 1998-04-15 2000-10-13 Forbedring av antistoff-cytokin fusjon protein-medierte immunoresponser ved ko-administrasjon med angiogeneseinhibator NO20005155L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8186398P 1998-04-15 1998-04-15
PCT/US1999/008335 WO1999052562A2 (en) 1998-04-15 1999-04-15 Enhancement of antibody-cytokine fusion protein mediated immune responses by co-administration with angiogenesis inhibitor

Publications (2)

Publication Number Publication Date
NO20005155D0 true NO20005155D0 (no) 2000-10-13
NO20005155L NO20005155L (no) 2000-12-13

Family

ID=22166892

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005155A NO20005155L (no) 1998-04-15 2000-10-13 Forbedring av antistoff-cytokin fusjon protein-medierte immunoresponser ved ko-administrasjon med angiogeneseinhibator

Country Status (19)

Country Link
US (1) US20040180035A1 (no)
EP (1) EP1071468B1 (no)
JP (1) JP2002511432A (no)
CN (1) CN1318092C (no)
AT (1) ATE329622T1 (no)
AU (1) AU758860B2 (no)
BR (1) BR9909583A (no)
CA (1) CA2328076C (no)
CZ (1) CZ20003767A3 (no)
DE (1) DE69931908T2 (no)
ES (1) ES2267263T3 (no)
HK (1) HK1038882A1 (no)
HU (1) HUP0101352A3 (no)
MX (1) MXPA00010070A (no)
NO (1) NO20005155L (no)
PL (1) PL343462A1 (no)
RU (1) RU2229305C2 (no)
WO (1) WO1999052562A2 (no)
ZA (1) ZA200005475B (no)

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AU4314801A (en) 2000-02-11 2001-08-20 Lexigen Pharm Corp Enhancing the circulating half-life of antibody-based fusion proteins
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CA2591297C (en) * 2004-12-09 2015-01-13 Stephen D. Gillies Il-7 variants with reduced immunogenicity
KR101030612B1 (ko) * 2005-10-21 2011-04-20 에프. 호프만-라 로슈 아게 폴리펩타이드의 재조합 발현 방법
DK2270050T3 (da) 2005-12-30 2013-08-12 Merck Patent Gmbh Anti-CD19-antistoffer med nedsat immunogenicitet
EA015338B1 (ru) * 2005-12-30 2011-06-30 Мерк Патент Гмбх ВАРИАНТЫ ИЛ-12p40 С УЛУЧШЕННОЙ СТАБИЛЬНОСТЬЮ
GB2441789B (en) * 2006-09-18 2012-03-28 Angus Buchan Gordon Use of a Tumour Volume Measuring Device
SG175233A1 (en) 2009-04-22 2011-11-28 Merck Patent Gmbh Antibody fusion proteins with modified fcrn binding sites
EP2561888A1 (en) * 2011-08-23 2013-02-27 Deutsches Krebsforschungszentrum Protein comprising NC-1 for treating angiogenesis-related diseases
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
CN104830901A (zh) * 2015-01-21 2015-08-12 武汉友芝友生物制药有限公司 一种鼠肿瘤模型的构建方法及其应用
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
US11779604B2 (en) 2016-11-03 2023-10-10 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses and methods
CN111094330A (zh) 2017-07-03 2020-05-01 转矩医疗股份有限公司 编码免疫刺激融合分子的多核苷酸及其用途

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Also Published As

Publication number Publication date
CA2328076A1 (en) 1999-10-21
AU3565099A (en) 1999-11-01
ES2267263T3 (es) 2007-03-01
WO1999052562A2 (en) 1999-10-21
HUP0101352A3 (en) 2003-08-28
US20040180035A1 (en) 2004-09-16
EP1071468A2 (en) 2001-01-31
ZA200005475B (en) 2001-11-13
HK1038882A1 (zh) 2002-04-04
MXPA00010070A (es) 2004-03-10
ATE329622T1 (de) 2006-07-15
RU2229305C2 (ru) 2004-05-27
WO1999052562A3 (en) 1999-11-18
CA2328076C (en) 2009-10-06
HUP0101352A2 (hu) 2001-08-28
EP1071468B1 (en) 2006-06-14
BR9909583A (pt) 2002-01-15
CN1318092C (zh) 2007-05-30
AU758860B2 (en) 2003-04-03
CZ20003767A3 (cs) 2002-01-16
JP2002511432A (ja) 2002-04-16
DE69931908D1 (de) 2006-07-27
DE69931908T2 (de) 2007-01-11
NO20005155L (no) 2000-12-13
CN1305386A (zh) 2001-07-25
PL343462A1 (en) 2001-08-13

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