NO20002050L - Aggregater av humaninsulinderivater - Google Patents

Aggregater av humaninsulinderivater

Info

Publication number
NO20002050L
NO20002050L NO20002050A NO20002050A NO20002050L NO 20002050 L NO20002050 L NO 20002050L NO 20002050 A NO20002050 A NO 20002050A NO 20002050 A NO20002050 A NO 20002050A NO 20002050 L NO20002050 L NO 20002050L
Authority
NO
Norway
Prior art keywords
aggregates
derivatives
human insulin
soluble
insulin derivatives
Prior art date
Application number
NO20002050A
Other languages
English (en)
Norwegian (no)
Other versions
NO20002050D0 (no
Inventor
Svend Havelund
Per Balschmidt
Ib Jonassen
Thomas Hoeg-Jensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO20002050D0 publication Critical patent/NO20002050D0/no
Publication of NO20002050L publication Critical patent/NO20002050L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
NO20002050A 1997-10-24 2000-04-18 Aggregater av humaninsulinderivater NO20002050L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK121897 1997-10-24
US6417097P 1997-11-04 1997-11-04
PCT/DK1998/000461 WO1999021888A1 (en) 1997-10-24 1998-10-23 Aggregates of human insulin derivatives

Publications (2)

Publication Number Publication Date
NO20002050D0 NO20002050D0 (no) 2000-04-18
NO20002050L true NO20002050L (no) 2000-06-23

Family

ID=26065414

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002050A NO20002050L (no) 1997-10-24 2000-04-18 Aggregater av humaninsulinderivater

Country Status (20)

Country Link
EP (1) EP1025125B1 (pt)
JP (1) JP2003525846A (pt)
KR (1) KR100539193B1 (pt)
CN (1) CN1240718C (pt)
AT (1) ATE243711T1 (pt)
AU (1) AU757933B2 (pt)
BR (1) BR9813128A (pt)
CA (1) CA2308705A1 (pt)
DE (1) DE69815877T2 (pt)
DK (1) DK1025125T3 (pt)
ES (1) ES2202899T3 (pt)
HU (1) HUP0004096A3 (pt)
IL (2) IL135400A0 (pt)
NO (1) NO20002050L (pt)
PL (1) PL195845B1 (pt)
PT (1) PT1025125E (pt)
RU (1) RU2218349C2 (pt)
UA (1) UA69393C2 (pt)
WO (1) WO1999021888A1 (pt)
ZA (1) ZA989722B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7316999B2 (en) 2000-06-02 2008-01-08 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives
AU2002303869B2 (en) 2001-05-21 2007-08-16 Novartis Ag Pulmonary administration of chemically modified insulin
US7317000B2 (en) 2001-12-02 2008-01-08 Novo Nordisk A/S Glucose-dependent insulins
EP1660531A2 (en) * 2003-08-05 2006-05-31 Novo Nordisk A/S Novel insulin derivatives
ES2472421T3 (es) * 2003-08-05 2014-07-01 Novo Nordisk A/S Nuevos derivados de insulina
BRPI0513508B1 (pt) * 2004-07-19 2021-06-01 Biocon Limited Conjugados de insulina-oligômero, formulações e usos desses
WO2006125765A2 (en) * 2005-05-26 2006-11-30 Novo Nordisk A/S Acylated insulin with high purity
EP1969004B1 (en) 2005-12-28 2011-08-10 Novo Nordisk A/S Compositions comprising an acylated insulin and zinc and method of making the said compositions
ATE482977T1 (de) 2006-02-27 2010-10-15 Novo Nordisk As Insulinderivate
US20090099064A1 (en) * 2006-06-08 2009-04-16 Diabecore Medical Inc., Derivatized insulin oligomers
JP5550338B2 (ja) 2006-07-31 2014-07-16 ノボ・ノルデイスク・エー/エス ペグ化持続型インスリン
CA2663074A1 (en) 2006-09-22 2008-03-27 Novo Nordisk A/S Protease resistant insulin analogues
EP2152245B1 (en) 2007-04-30 2015-12-02 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
WO2008152106A1 (en) 2007-06-13 2008-12-18 Novo Nordisk A/S Pharmaceutical formulation comprising an insulin derivative
US9260502B2 (en) 2008-03-14 2016-02-16 Novo Nordisk A/S Protease-stabilized insulin analogues
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
WO2010049488A1 (en) 2008-10-30 2010-05-06 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
RU2013123515A (ru) 2010-10-27 2014-12-10 Ново Нордиск А/С Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами
CN103191416A (zh) * 2012-01-05 2013-07-10 四川大学 一种猪胰岛素超分子聚集体及其制备方法
KR20150002777A (ko) 2012-04-11 2015-01-07 노보 노르디스크 에이/에스 인슐린 제제
JP2016519127A (ja) 2013-04-30 2016-06-30 ノヴォ ノルディスク アー/エス 新規投与レジメン
PL3055325T3 (pl) 2013-10-07 2018-06-29 Novo Nordisk A/S Nowa pochodna analogu insuliny
AR099569A1 (es) 2014-02-28 2016-08-03 Novo Nordisk As Derivados de insulina y los usos médicos de estos
DK3554534T3 (da) 2016-12-16 2021-08-23 Novo Nordisk As Farmaceutisk sammensætning omfattende insulin
CN111050750A (zh) 2017-08-24 2020-04-21 诺沃挪第克公司 Glp-1组合物及其用途
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
CN115135305A (zh) 2020-02-18 2022-09-30 诺和诺德股份有限公司 药物制剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559094A (en) * 1994-08-02 1996-09-24 Eli Lilly And Company AspB1 insulin analogs
US6451970B1 (en) * 1996-02-21 2002-09-17 Novo Nordisk A/S Peptide derivatives

Also Published As

Publication number Publication date
NO20002050D0 (no) 2000-04-18
PT1025125E (pt) 2003-11-28
EP1025125A1 (en) 2000-08-09
JP2003525846A (ja) 2003-09-02
KR20010031247A (ko) 2001-04-16
AU757933B2 (en) 2003-03-13
UA69393C2 (uk) 2004-09-15
CA2308705A1 (en) 1999-05-06
ES2202899T3 (es) 2004-04-01
EP1025125B1 (en) 2003-06-25
AU9622198A (en) 1999-05-17
DK1025125T3 (da) 2003-10-06
ZA989722B (en) 1999-04-26
HUP0004096A3 (en) 2001-12-28
KR100539193B1 (ko) 2005-12-27
DE69815877T2 (de) 2004-05-19
CN1281466A (zh) 2001-01-24
DE69815877D1 (de) 2003-07-31
PL340032A1 (en) 2001-01-15
ATE243711T1 (de) 2003-07-15
BR9813128A (pt) 2000-08-15
RU2218349C2 (ru) 2003-12-10
IL135400A0 (en) 2001-05-20
IL135400A (en) 2007-08-19
CN1240718C (zh) 2006-02-08
PL195845B1 (pl) 2007-10-31
HUP0004096A2 (hu) 2001-05-28
WO1999021888A1 (en) 1999-05-06

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application