NO1999012I1 - Ropinirole hydroklorid - Google Patents

Ropinirole hydroklorid

Info

Publication number
NO1999012I1
NO1999012I1 NO1999012C NO1999012C NO1999012I1 NO 1999012 I1 NO1999012 I1 NO 1999012I1 NO 1999012 C NO1999012 C NO 1999012C NO 1999012 C NO1999012 C NO 1999012C NO 1999012 I1 NO1999012 I1 NO 1999012I1
Authority
NO
Norway
Prior art keywords
ropinirole hydrochloride
ropinirole
hydrochloride
Prior art date
Application number
NO1999012C
Other languages
English (en)
Original Assignee
Smithkline & French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline & French Laboratories Ltd filed Critical Smithkline & French Laboratories Ltd
Publication of NO1999012I1 publication Critical patent/NO1999012I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/39—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups
    • C07C205/40—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by esterified hydroxy groups having nitro groups and esterified hydroxy groups bound to acyclic carbon atoms of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO1999012C 1990-04-17 1999-06-18 Ropinirole hydroklorid NO1999012I1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909008605A GB9008605D0 (en) 1990-04-17 1990-04-17 Process

Publications (1)

Publication Number Publication Date
NO1999012I1 true NO1999012I1 (no) 1999-06-18

Family

ID=10674534

Family Applications (2)

Application Number Title Priority Date Filing Date
NO924028A NO178396C (no) 1990-04-17 1992-10-16 Forbedret fremgangsmåte for fremstilling av substituerte indolonderivater og mellomprodukter i fremstillingen derav
NO1999012C NO1999012I1 (no) 1990-04-17 1999-06-18 Ropinirole hydroklorid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO924028A NO178396C (no) 1990-04-17 1992-10-16 Forbedret fremgangsmåte for fremstilling av substituerte indolonderivater og mellomprodukter i fremstillingen derav

Country Status (29)

Country Link
US (1) US5336781A (no)
EP (1) EP0526529B1 (no)
JP (2) JP2788548B2 (no)
KR (1) KR0180215B1 (no)
CN (1) CN1027892C (no)
AP (1) AP184A (no)
AT (1) ATE144251T1 (no)
AU (2) AU640006B2 (no)
CA (1) CA2080221C (no)
CY (1) CY1981A (no)
DE (1) DE69122753T2 (no)
DK (1) DK0526529T3 (no)
ES (1) ES2094812T3 (no)
FI (1) FI101148B (no)
GB (1) GB9008605D0 (no)
GR (1) GR3022261T3 (no)
HK (1) HK3097A (no)
HU (1) HU214822B (no)
IE (1) IE911262A1 (no)
IL (7) IL97867A (no)
MA (1) MA22133A1 (no)
MY (1) MY109628A (no)
NO (2) NO178396C (no)
NZ (1) NZ237819A (no)
PL (1) PL166736B1 (no)
PT (1) PT97375B (no)
SA (1) SA91110352B1 (no)
WO (1) WO1991016306A1 (no)
ZA (1) ZA912782B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008605D0 (en) * 1990-04-17 1990-06-13 Smith Kline French Lab Process
DK0547165T3 (da) * 1990-09-28 2000-03-27 Smithkline Beecham Corp Fremgangsmåde til fremstilling af vandopløselige camptothecinanaloger såvel som forbindelserne 10-hydroxy-11-C(1-6)-alkoxyc
GB9300309D0 (en) * 1993-01-08 1993-03-03 Smithkline Beecham Plc Process
US6218421B1 (en) * 1999-07-01 2001-04-17 Smithkline Beecham P.L.C. Method of promoting smoking cessation
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
WO2005074387A2 (en) * 2003-12-30 2005-08-18 Sun Pharmaceutical Industries Limited Novel crystal forms of 4-[2-di-n-propylamino)ethyl]-2 (3h)- indolone hydrochloride
US7378439B2 (en) * 2004-01-20 2008-05-27 Usv, Ltd. Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride
WO2005105741A1 (en) * 2004-02-11 2005-11-10 Sun Pharmaceutical Industries Limited Substantially pure 4-[2-(di-n-propylamino)ethyl]-2(3h)-indolone hydrochloride
WO2005080333A1 (en) * 2004-02-19 2005-09-01 Torrent Pharmaceuticals Ltd Process for purification of ropinirole
US20070254941A1 (en) * 2006-04-21 2007-11-01 Glenmark Pharmaceuticals Limited Subtantially pure ropinirole hydrochloride, polymorphic form of ropinirole and process for their preparation
CN103130704B (zh) * 2013-03-11 2019-03-22 上海奥博生物医药技术有限公司 一种制备4-(2-羟乙基)-1，3-二氢-2h-吲哚-2-酮的新方法
CN103145604A (zh) * 2013-03-19 2013-06-12 上海奥博生物医药技术有限公司 一种制备罗匹尼罗关键中间体的方法
CN105418482A (zh) * 2015-11-23 2016-03-23 东南大学 一种改进的盐酸罗匹尼罗的制备方法
CN108440376B (zh) * 2018-05-08 2020-06-05 中国科学院成都生物研究所 一种盐酸罗匹尼罗的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1154976A (en) * 1967-02-21 1969-06-11 Pfizer Ltd N-Phenyl Indoline Derivatives
JPS53101333A (en) * 1977-02-14 1978-09-04 Sagami Chem Res Center 3-acyloxymethyl-3,4:5,6-diepoxycyclohexane-1,2-diol and
IT1171624B (it) * 1980-11-12 1987-06-10 Thomae Gmbh Dr K Indolinoni dotati di proprieta' farmaceutiche e procedimento per la loro produzione
US4588790A (en) * 1982-03-24 1986-05-13 Union Carbide Corporation Method for fluidized bed polymerization
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US4593033A (en) * 1985-04-24 1986-06-03 Merck & Co., Inc. Substituted indeno[2,1-c] pyridines useful as calcium channel blockers
GB8712073D0 (en) * 1987-05-21 1987-06-24 Smith Kline French Lab Medicament
GB8714371D0 (en) * 1987-06-19 1987-07-22 Smith Kline French Lab Process
FR2635104B1 (fr) * 1988-08-03 1992-04-30 Synthelabo Derives d'indolone, leur preparation et leur application en therapeutique
GB9008605D0 (en) * 1990-04-17 1990-06-13 Smith Kline French Lab Process

Also Published As

Publication number Publication date
AU646771B2 (en) 1994-03-03
JPH10251205A (ja) 1998-09-22
AP9100251A0 (en) 1991-04-30
IL111028A (en) 1995-11-27
JPH05506029A (ja) 1993-09-02
CN1056686A (zh) 1991-12-04
AU7656291A (en) 1991-11-11
MY109628A (en) 1997-03-31
CY1981A (en) 1997-09-05
IL111030A (en) 1995-11-27
DK0526529T3 (da) 1996-11-18
DE69122753D1 (de) 1996-11-21
NO178396C (no) 1996-03-20
ATE144251T1 (de) 1996-11-15
CA2080221A1 (en) 1991-10-18
FI924674A0 (fi) 1992-10-15
HUT64742A (en) 1994-02-28
CN1027892C (zh) 1995-03-15
JP3044013B2 (ja) 2000-05-22
MA22133A1 (fr) 1991-12-31
PT97375B (pt) 1998-08-31
HU214822B (hu) 1998-06-29
HU9203261D0 (en) 1992-12-28
NO178396B (no) 1995-12-11
PL166736B1 (pl) 1995-06-30
AP184A (en) 1992-06-30
IL97867A (en) 1995-11-27
IL111030A0 (en) 1994-11-28
FI101148B (fi) 1998-04-30
IL111028A0 (en) 1994-11-28
FI924674A (fi) 1992-10-15
HK3097A (en) 1997-01-10
IL111029A (en) 1995-11-27
KR0180215B1 (ko) 1999-03-20
IL97867A0 (en) 1992-06-21
IL111029A0 (en) 1994-11-28
CA2080221C (en) 2000-11-14
NO924028D0 (no) 1992-10-16
DE69122753T2 (de) 1997-05-07
AU3566993A (en) 1993-06-03
AU640006B2 (en) 1993-08-12
ZA912782B (en) 1992-11-25
EP0526529B1 (en) 1996-10-16
SA91110352B1 (ar) 2001-11-12
WO1991016306A1 (en) 1991-10-31
GB9008605D0 (en) 1990-06-13
ES2094812T3 (es) 1997-02-01
GR3022261T3 (en) 1997-04-30
NO924028L (no) 1992-10-16
US5336781A (en) 1994-08-09
PT97375A (pt) 1992-01-31
IE911262A1 (en) 1991-10-23
NZ237819A (en) 1993-05-26
EP0526529A1 (en) 1993-02-10
JP2788548B2 (ja) 1998-08-20

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