NO180230C - 2-amino-1,2,3,4-tetrahydronaftalenderivater med kardiovaskulær aktivitet samt farmasöytiske preparater inneholdende slike - Google Patents

2-amino-1,2,3,4-tetrahydronaftalenderivater med kardiovaskulær aktivitet samt farmasöytiske preparater inneholdende slike

Info

Publication number
NO180230C
NO180230C NO934160A NO934160A NO180230C NO 180230 C NO180230 C NO 180230C NO 934160 A NO934160 A NO 934160A NO 934160 A NO934160 A NO 934160A NO 180230 C NO180230 C NO 180230C
Authority
NO
Norway
Prior art keywords
amino
pharmaceutical preparations
preparations containing
cardiovascular activity
tetrahydronaphthalene derivatives
Prior art date
Application number
NO934160A
Other languages
English (en)
Norwegian (no)
Other versions
NO934160D0 (no
NO934160L (no
NO180230B (no
Inventor
Francesco Santangelo
Giorgio Bertolini
Cesare Casagrande
Francesco Marchini
Stefania Montanari
Claudio Semeraro
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of NO934160D0 publication Critical patent/NO934160D0/no
Publication of NO934160L publication Critical patent/NO934160L/no
Publication of NO180230B publication Critical patent/NO180230B/no
Publication of NO180230C publication Critical patent/NO180230C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO934160A 1992-03-17 1993-11-17 2-amino-1,2,3,4-tetrahydronaftalenderivater med kardiovaskulær aktivitet samt farmasöytiske preparater inneholdende slike NO180230C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI920608A IT1254521B (it) 1992-03-17 1992-03-17 Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare
PCT/EP1993/000577 WO1993019036A1 (en) 1992-03-17 1993-03-13 2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them

Publications (4)

Publication Number Publication Date
NO934160D0 NO934160D0 (no) 1993-11-17
NO934160L NO934160L (no) 1993-11-17
NO180230B NO180230B (no) 1996-12-02
NO180230C true NO180230C (no) 1997-03-12

Family

ID=11362451

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934160A NO180230C (no) 1992-03-17 1993-11-17 2-amino-1,2,3,4-tetrahydronaftalenderivater med kardiovaskulær aktivitet samt farmasöytiske preparater inneholdende slike

Country Status (20)

Country Link
US (2) US5407956A (it)
EP (1) EP0585440B1 (it)
JP (1) JP3231775B2 (it)
KR (1) KR100283945B1 (it)
AT (1) ATE137737T1 (it)
CA (1) CA2102490C (it)
DE (1) DE69302544T2 (it)
DK (1) DK0585440T3 (it)
ES (1) ES2087729T3 (it)
FI (1) FI935066A0 (it)
GR (1) GR3020419T3 (it)
HU (2) HUT68936A (it)
IT (1) IT1254521B (it)
MD (1) MD1449G2 (it)
NO (1) NO180230C (it)
NZ (1) NZ249845A (it)
OA (1) OA09843A (it)
PL (2) PL171844B1 (it)
RU (1) RU2120435C1 (it)
WO (1) WO1993019036A1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271411B (it) * 1993-09-14 1997-05-28 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare
IT1274673B (it) * 1994-04-14 1997-07-24 Zambon Spa Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari
IT1270260B (it) * 1994-06-21 1997-04-29 Zambon Spa Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
IT1271008B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare
IT1271009B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
IT1271007B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidronaftalene attivi sul sistema cardiovascolare
IT1273455B (it) * 1995-01-27 1997-07-08 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
IT1276710B1 (it) * 1995-06-14 1997-11-03 Zambon Spa Derivati dell'acido fosfinico ad attivita' inibitrice delle metallopeptidasi
GB9625455D0 (en) * 1996-12-07 1997-01-22 Glaxo Group Ltd Process for resolving mixtures of carbocyclic steroisomers
IT1289980B1 (it) * 1997-02-26 1998-10-19 Zambon Spa Derivati idrossimetilici del 2-ammino-1,2,3,4-tetraidronaftalene attivi in campo cardiovascolare
JP5748666B2 (ja) * 2008-12-09 2015-07-15 インテルキム、ソシエダッド アノニマ （６ｓ）−（−）−５，６，７，８−テトラヒドロ−６−［プロピル−（２−チエニル）エチル］アミノ−１−ナフトール（ロチゴチン）の製造のための方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072061B1 (en) * 1981-08-05 1985-05-15 FISONS plc Amine derivatives, processes for their production and pharmaceutical compositions containing them
EP0142283B1 (en) * 1983-10-25 1991-01-30 FISONS plc Phenylethylamines, process for their preparation and compositions containing them
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare

Also Published As

Publication number Publication date
US5451608A (en) 1995-09-19
DE69302544T2 (de) 1996-09-19
DK0585440T3 (da) 1996-06-10
WO1993019036A1 (en) 1993-09-30
OA09843A (en) 1994-08-15
HU211517A9 (en) 1995-11-28
MD1449F1 (en) 2000-04-30
ATE137737T1 (de) 1996-05-15
CA2102490C (en) 2004-06-08
AU650201B2 (en) 1994-06-09
DE69302544D1 (de) 1996-06-13
EP0585440A1 (en) 1994-03-09
ITMI920608A1 (it) 1993-09-17
CA2102490A1 (en) 1993-09-18
EP0585440B1 (en) 1996-05-08
JPH06507920A (ja) 1994-09-08
ITMI920608A0 (it) 1992-03-17
FI935066A (fi) 1993-11-16
MD1449G2 (ro) 2000-12-31
PL171844B1 (pl) 1997-06-30
US5407956A (en) 1995-04-18
NO934160D0 (no) 1993-11-17
RU2120435C1 (ru) 1998-10-20
MD960271A (en) 1997-09-30
JP3231775B2 (ja) 2001-11-26
GR3020419T3 (en) 1996-10-31
PL172056B1 (pl) 1997-07-31
NZ249845A (en) 1996-03-26
KR100283945B1 (ko) 2001-03-02
HUT68936A (en) 1995-08-28
FI935066A0 (fi) 1993-11-16
ES2087729T3 (es) 1996-07-16
AU3747893A (en) 1993-10-21
NO934160L (no) 1993-11-17
NO180230B (no) 1996-12-02
IT1254521B (it) 1995-09-25

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