NO179611C - Fremgangsmåte for fremstilling av et inklusjonskompleks av N-etoksykarbonyl-3-morfolinosydnonimin eller dets salt dannet med et syklodekstrinderivat - Google Patents

Fremgangsmåte for fremstilling av et inklusjonskompleks av N-etoksykarbonyl-3-morfolinosydnonimin eller dets salt dannet med et syklodekstrinderivat

Info

Publication number
NO179611C
NO179611C NO914649A NO914649A NO179611C NO 179611 C NO179611 C NO 179611C NO 914649 A NO914649 A NO 914649A NO 914649 A NO914649 A NO 914649A NO 179611 C NO179611 C NO 179611C
Authority
NO
Norway
Prior art keywords
cyclodextrin
ethoxycarbonyl
beta
morpholinosydnonimine
preparation
Prior art date
Application number
NO914649A
Other languages
English (en)
Norwegian (no)
Other versions
NO179611B (no
NO914649D0 (no
NO914649L (no
Inventor
Maria Vikmon
Jozsef Szejtli
Jozsef Gaal
Istvan Hermecz
Agnes Hovarth
Katalin Marmarosi
Gabor Hovarth
Iren Munkacsi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of NO914649D0 publication Critical patent/NO914649D0/no
Publication of NO914649L publication Critical patent/NO914649L/no
Publication of NO179611B publication Critical patent/NO179611B/no
Publication of NO179611C publication Critical patent/NO179611C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/041,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO914649A 1990-03-28 1991-11-27 Fremgangsmåte for fremstilling av et inklusjonskompleks av N-etoksykarbonyl-3-morfolinosydnonimin eller dets salt dannet med et syklodekstrinderivat NO179611C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU901868A HU210921B (en) 1990-03-28 1990-03-28 Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them
PCT/HU1991/000012 WO1991014680A1 (en) 1990-03-28 1991-03-28 Inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine or salts formed with cyclodextrin derivatives, preparation thereof and pharmaceutical compositions containing the same

Publications (4)

Publication Number Publication Date
NO914649D0 NO914649D0 (no) 1991-11-27
NO914649L NO914649L (no) 1991-11-27
NO179611B NO179611B (no) 1996-08-05
NO179611C true NO179611C (no) 1996-11-13

Family

ID=10956592

Family Applications (1)

Application Number Title Priority Date Filing Date
NO914649A NO179611C (no) 1990-03-28 1991-11-27 Fremgangsmåte for fremstilling av et inklusjonskompleks av N-etoksykarbonyl-3-morfolinosydnonimin eller dets salt dannet med et syklodekstrinderivat

Country Status (34)

Country Link
US (1) US5403840A (bg)
EP (1) EP0477315B1 (bg)
JP (1) JP2582497B2 (bg)
KR (1) KR950004705B1 (bg)
CN (1) CN1051080C (bg)
AT (1) ATE138656T1 (bg)
AU (1) AU638824B2 (bg)
BG (1) BG61689B1 (bg)
BR (1) BR9105136A (bg)
CA (1) CA2054188C (bg)
CZ (1) CZ287353B6 (bg)
DE (1) DE69119853T2 (bg)
DK (1) DK0477315T3 (bg)
ES (1) ES2090320T3 (bg)
FI (1) FI102460B1 (bg)
GE (1) GEP19991832B (bg)
GR (1) GR3020684T3 (bg)
HR (1) HRP920561B1 (bg)
HU (1) HU210921B (bg)
IL (1) IL97714A (bg)
LT (1) LT3394B (bg)
LV (1) LV10245B (bg)
MC (1) MC2185A1 (bg)
MD (1) MD679G2 (bg)
NO (1) NO179611C (bg)
OA (1) OA10029A (bg)
PL (1) PL165868B1 (bg)
RO (1) RO109649B1 (bg)
RU (1) RU2111216C1 (bg)
SI (1) SI9110908A (bg)
SK (1) SK279891B6 (bg)
TJ (1) TJ231R3 (bg)
UA (1) UA27226C2 (bg)
WO (1) WO1991014680A1 (bg)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
GB2290964A (en) * 1994-07-08 1996-01-17 Arto Olavi Urtti Transdermal drug delivery system
GB9915231D0 (en) 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
FR2805462B1 (fr) 2000-02-24 2003-08-15 Therabel Res Nouvelle forme galenique orale a liberation prolongee de la molsidomine
ITTO20120056A1 (it) * 2012-01-24 2013-07-25 Borla Ind Connettore per linee medicali di infusione, trasfusione e simili
ITTO20130433A1 (it) * 2013-05-29 2014-11-30 Borla Ind Connettore per linee medicali
BE1028879B1 (fr) 2020-12-11 2022-07-12 Europharmaceuticals Comprimé à libération prolongée de la molsidomine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695897C3 (de) * 1966-07-04 1979-02-15 Takeda Chemical Industries Ltd N-Acyl-sydnonimine, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3221425A1 (de) * 1982-06-07 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette
DK243084A (da) 1983-05-26 1984-11-27 Takeda Chemical Industries Ltd Perkutane farmaceutiske praeparater til udvortes brug
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
DE3522191A1 (de) * 1985-06-21 1987-01-15 Cassella Ag Photostabilisierung von sydnoniminen
GB8613688D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
JPH0819004B2 (ja) * 1986-12-26 1996-02-28 日清製粉株式会社 徐放性医薬製剤
IT1204725B (it) * 1987-06-17 1989-03-10 Edmond Pharma Srl Complessi di inclusione del dipiridamolo con ciclodestrine
ES2037385T3 (es) * 1988-01-14 1993-06-16 Akzo N.V. Un procedimiento de manufactura de una preparacion farmaceutica para administracion local.
US5120732A (en) * 1988-06-14 1992-06-09 Cassella Aktiengesellschaft Substituted 3-aminosyndone imines, a process for their preparation and their use
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione
SE8904296D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
HU211648A9 (en) * 1990-03-28 1995-12-28 Chinoin Gyogyszer Es Vegyeszet Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof, and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
HRP920561A2 (hr) 1994-04-30
LV10245A (lv) 1994-10-20
MD679G2 (ro) 1997-11-30
WO1991014680A1 (en) 1991-10-03
NO179611B (no) 1996-08-05
SK279891B6 (sk) 1999-05-07
NO914649D0 (no) 1991-11-27
LTIP386A (en) 1994-12-27
CN1051080C (zh) 2000-04-05
FI915569A0 (fi) 1991-11-26
HU901868D0 (en) 1990-08-28
SI9110908A (sl) 1998-06-30
HRP920561B1 (en) 1999-12-31
KR920701182A (ko) 1992-08-11
EP0477315A1 (en) 1992-04-01
CA2054188A1 (en) 1991-09-29
BR9105136A (pt) 1992-08-04
BG95531A (bg) 1993-12-24
NO914649L (no) 1991-11-27
ES2090320T3 (es) 1996-10-16
RO109649B1 (ro) 1995-04-28
OA10029A (en) 1996-10-14
CS85191A3 (en) 1991-11-12
ATE138656T1 (de) 1996-06-15
GR3020684T3 (en) 1996-10-31
JPH04506362A (ja) 1992-11-05
AU638824B2 (en) 1993-07-08
DE69119853D1 (de) 1996-07-04
MC2185A1 (fr) 1992-09-16
DE69119853T2 (de) 1996-10-10
US5403840A (en) 1995-04-04
RU2111216C1 (ru) 1998-05-20
PL165868B1 (pl) 1995-02-28
PL293022A1 (en) 1992-12-28
FI102460B (fi) 1998-12-15
IL97714A0 (en) 1992-06-21
LT3394B (en) 1995-09-25
CA2054188C (en) 1996-07-23
TJ231R3 (en) 1999-11-24
HUT58109A (en) 1992-01-28
LV10245B (en) 1995-08-20
DK0477315T3 (da) 1996-09-30
CZ287353B6 (cs) 2000-11-15
CN1056688A (zh) 1991-12-04
HU210921B (en) 1995-09-28
AU7574591A (en) 1991-10-21
BG61689B1 (bg) 1998-03-31
FI102460B1 (fi) 1998-12-15
UA27226C2 (uk) 2000-08-15
EP0477315B1 (en) 1996-05-29
IL97714A (en) 1995-03-30
MD679F1 (en) 1997-02-28
KR950004705B1 (ko) 1995-05-04
JP2582497B2 (ja) 1997-02-19
GEP19991832B (en) 1999-11-05

Similar Documents

Publication Publication Date Title
NO179611C (no) Fremgangsmåte for fremstilling av et inklusjonskompleks av N-etoksykarbonyl-3-morfolinosydnonimin eller dets salt dannet med et syklodekstrinderivat
HUT62198A (en) Erythropoietin compositions comprising cyclodextrin
CA2119154A1 (en) Derivatives of Cyclodextrins Exhibiting Enhanced Aqueous Solubility and the Use Thereof
EP0803243A3 (en) Cyclodextrins and phenolic compounds in dental products
ATE178321T1 (de) Verfahren zur herstellung von n-beta-g(b)- hydroxyalkyl-tri-n-carboxyalkyl-1,4,7,10- tetraazacyclododecan- und n-beta-g(b)- hydroxyalkyl-tri-n-carboxyalkyl-1,4,8,11- tetraazacyclotetradecan-derivaten und deren metallkomplexe
EP0698018B1 (en) Inclusion complexes of taxol or taxotere or taxus extract formed with cyclodextrins, their preparation and use
DE50011006D1 (de) Molekulargewichtsaufbau und Modifizierung von Polykondensaten
AU3854095A (en) Novel complexes and their compositions
DE69214355D1 (de) Hepatozytwachstumsfaktor enthaltende Mittel
EP0931545A3 (en) Droloxifene pharmaceutical compositions
PT91088A (pt) Processo de preparacao de composicoes a base de alfa-,beta- ou gama- -cilcodextrinas
Maaroufi et al. Mechanism of thrombin inhibition by heparin cofactor II in the presence of dermatan sulphates, native or oversulphated, and a heparin-like dextran derivative
FI102462B1 (fi) Menetelmä nimesulidin syklodekstriinikompleksin valmistamiseksi
AU8221291A (en) Cyclopentane derivatives, process for producing them and their pharmaceutical use
DE69618496T2 (de) Verfahren zur Derivatisierung von Polyglukosaminen
ES2094080B1 (es) Procedimiento de preparacion de complejos de inclusion de tenoxicam con ciclodextrinas.
Lee et al. Phamaceutical Studies on the Drug (III)-Enhancement of Dissolution and Stability of Sulfamethoxazole by ${\beta}-Cyclodextrin $ Complexation

Legal Events

Date Code Title Description
MK1K Patent expired