NO179479C - Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat - Google Patents

Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat

Info

Publication number
NO179479C
NO179479C NO891007A NO891007A NO179479C NO 179479 C NO179479 C NO 179479C NO 891007 A NO891007 A NO 891007A NO 891007 A NO891007 A NO 891007A NO 179479 C NO179479 C NO 179479C
Authority
NO
Norway
Prior art keywords
carboxylic acid
nonionic surfactant
aliphatic carboxylic
preparation
biologically active
Prior art date
Application number
NO891007A
Other languages
English (en)
Norwegian (no)
Other versions
NO891007L (no
NO179479B (no
NO891007D0 (no
Inventor
Takeru Fujii
Seiichi Sako
Shigeyuki Takama
Toru Hibi
Akiya Yamada
Original Assignee
Teikoku Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Seiyaku Kk filed Critical Teikoku Seiyaku Kk
Publication of NO891007D0 publication Critical patent/NO891007D0/no
Publication of NO891007L publication Critical patent/NO891007L/no
Publication of NO179479B publication Critical patent/NO179479B/no
Publication of NO179479C publication Critical patent/NO179479C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO891007A 1988-03-11 1989-03-09 Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat NO179479C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16716388A 1988-03-11 1988-03-11
US31550289A 1989-03-01 1989-03-01

Publications (4)

Publication Number Publication Date
NO891007D0 NO891007D0 (no) 1989-03-09
NO891007L NO891007L (no) 1989-09-12
NO179479B NO179479B (no) 1996-07-08
NO179479C true NO179479C (no) 1996-10-16

Family

ID=26862907

Family Applications (1)

Application Number Title Priority Date Filing Date
NO891007A NO179479C (no) 1988-03-11 1989-03-09 Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat

Country Status (14)

Country Link
US (2) US5840685A (ja)
EP (1) EP0332222B1 (ja)
JP (1) JP2801249B2 (ja)
KR (1) KR0138658B1 (ja)
AT (1) ATE128874T1 (ja)
AU (1) AU617157B2 (ja)
CA (1) CA1336676C (ja)
CZ (1) CZ278971B6 (ja)
DE (2) DE68924491T2 (ja)
DK (1) DK116789A (ja)
ES (1) ES2078222T3 (ja)
GR (1) GR900300006T1 (ja)
NO (1) NO179479C (ja)
NZ (1) NZ228285A (ja)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981485A (en) 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
JP2911496B2 (ja) * 1989-09-11 1999-06-23 帝國製薬株式会社 生理活性ポリペプチド含有高吸収性経膣剤
JPH078804B2 (ja) * 1990-08-28 1995-02-01 三菱化学株式会社 副腎皮質刺激ホルモン放出因子含有製剤
JP3628713B2 (ja) * 1993-06-07 2005-03-16 帝國製薬株式会社 生理学的に活性なペプチドを含有する膣投与製剤
ATE215382T1 (de) * 1994-12-29 2002-04-15 Mochida Pharm Co Ltd Ulinastatin enthaltende zäpfchen
GB9516268D0 (en) * 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon
GB2318056B (en) * 1995-08-08 1999-05-26 Danbiosyst Uk Composition for enhanced uptake of polar drugs from the colon
US6093394A (en) * 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US8765177B2 (en) 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
US7658938B2 (en) * 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
US8119159B2 (en) * 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
ATE306489T1 (de) 1999-03-08 2005-10-15 Medicure Inc Pyridoxal-analoge zur behandlung von störungen ausgelöst durch einen vitamin b6 mangel
EP1187639A1 (en) 1999-06-04 2002-03-20 Delrx Pharmaceutical Corporation Formulations comprising dehydrated particles of pharmaceutical agents and process for preparing the same
AU5840200A (en) * 1999-07-13 2001-01-30 Medicure Inc. Treatment of diabetes and related pathologies
WO2001013900A2 (en) 1999-08-24 2001-03-01 Medicure International Inc. Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
DE60110054T2 (de) 2000-02-29 2006-03-09 Medicure International Inc. Cardioprotektive phosphonate
US6586414B2 (en) 2000-03-28 2003-07-01 Medicure International Inc. Treatment of cerebrovascular disease
US6737084B2 (en) 2000-06-27 2004-05-18 Qualilife Compositions and methods for enhancing or treating female sexual response
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
NZ523815A (en) 2000-07-07 2004-07-30 Medicure Int Inc Pyridoxine and pyridoxal analogues: cardiovascular therapeutics
EP1339312B1 (en) * 2000-10-10 2006-01-04 Microchips, Inc. Microchip reservoir devices using wireless transmission of power and data
US6875208B2 (en) * 2001-05-31 2005-04-05 Massachusetts Institute Of Technology Microchip devices with improved reservoir opening
DE60202468T2 (de) 2001-06-28 2006-02-16 Microchips, Inc., Bedford Verfahren zum hermetischen versiegeln von mikrochip-reservoir-vorrichtungen
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
AU2003266142A1 (en) * 2002-09-12 2004-04-30 Biosyn, Inc. Mucus formulation for mucosal surfaces and uses thereof
US20040186077A1 (en) * 2003-03-17 2004-09-23 Medicure International Inc. Novel heteroaryl phosphonates as cardioprotective agents
EP1620060B1 (en) * 2003-04-29 2010-03-24 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
WO2006097793A2 (en) * 2004-04-15 2006-09-21 Chiasma, Ltd. Compositions capable of facilitating penetration across a biological barrier
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
WO2006050598A1 (en) 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
US7459468B2 (en) 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
WO2006081279A2 (en) * 2005-01-25 2006-08-03 Microchips, Inc. Control of drug release by transient modification of local microenvironments
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
MX2008012678A (es) * 2006-04-07 2008-12-17 Merrion Res Iii Ltd Forma de dosis oral solida que contiene un mejorador.
CA2654566A1 (en) * 2006-06-09 2007-12-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
KR20110007242A (ko) * 2008-05-07 2011-01-21 메리온 리서치 Ⅲ 리미티드 펩티드 조성물 및 그의 제조 방법
NZ591810A (en) 2008-09-17 2012-12-21 Chiasma Inc Pharmaceutical compositions and related methods of delivery the composition comprises a medium chain fatty acid
JP5409067B2 (ja) * 2009-03-23 2014-02-05 ユニ・チャーム株式会社 タンポン
US9089484B2 (en) 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
CN103476419A (zh) 2011-01-07 2013-12-25 梅里翁第三研究有限公司 口服投药的含铁药物组合物
ES2975708T3 (es) 2015-01-29 2024-07-12 Novo Nordisk As Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico
US10238709B2 (en) 2015-02-03 2019-03-26 Chiasma, Inc. Method of treating diseases
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888838A (en) * 1972-07-10 1975-06-10 Ayerst Mckenna & Harrison Decapeptide having luteinizing hormone (lh)-and follicle stimulating hormone (fsh)-releasing activity, salts and compositions thereof, a process for preparing same, and intermediates therefor
JPS563846B2 (ja) * 1972-10-12 1981-01-27
US4083967A (en) * 1973-11-01 1978-04-11 Burroughs Wellcome Co. Nona- and decapeptides
US4010125A (en) * 1975-06-12 1977-03-01 Schally Andrew Victor [D-Trp6 ]-LH-RH and intermediates therefor
US4018726A (en) * 1975-06-12 1977-04-19 Andrew Victor Schally [D-Phe6 ]-LH-RH and intermediates therefor
IL54041A (en) * 1978-02-13 1981-05-20 Yissum Res Dev Co Pharmaceutical compositions for enteral or vaginal application comprising the active ingredient and a nonionic surfactant
JPS55153712A (en) * 1979-05-18 1980-11-29 Kao Corp Insulin pharmaceutical preparation and its production
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
JPS56122309A (en) * 1980-03-03 1981-09-25 Teijin Ltd Calcitonin pharmaceutical for rectal administration
JPS5885813A (ja) * 1981-11-17 1983-05-23 Toyo Jozo Co Ltd 吸収性良好な製剤
NL193099C (nl) * 1981-10-30 1998-11-03 Novo Industri As Gestabiliseerde insuline-oplossing.
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
JPS5921613A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd 直腸投与製剤
GB2127689B (en) * 1982-10-05 1986-07-09 Sandoz Ltd Calcitonin inhalation compositions
EP0166971B1 (de) * 1984-06-09 1990-02-28 Hoechst Aktiengesellschaft Insulinzubereitungen, Verfahren zu deren Herstellung und deren Verwendung
JPS61267528A (ja) * 1984-11-26 1986-11-27 Yamanouchi Pharmaceut Co Ltd 吸収促進剤を含有するカルシトニン経鼻剤
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
JPS6236498A (ja) * 1985-08-09 1987-02-17 ル・エ−ル・リクイツド・ソシエテ・アノニム・プ−ル・ル・エチユド・エ・ル・エクスプルワテシヨン・デ・プロセデ・ジエオルジエ・クロ−ド セルロ−ス保護剤
DE3603444A1 (de) * 1986-02-05 1987-08-06 Thomae Gmbh Dr K Pharmazeutische zubereitungsformen zur stabilisierung von interferon alpha
GR871067B (en) * 1986-07-18 1987-11-19 Chugai Pharmaceutical Co Ltd Process for producing stable pharmaceutical preparation containing granulocyte colony stimulating factor

Also Published As

Publication number Publication date
DE68924491T2 (de) 1996-03-21
AU617157B2 (en) 1991-11-21
US5824646A (en) 1998-10-20
EP0332222B1 (en) 1995-10-11
ATE128874T1 (de) 1995-10-15
GR900300006T1 (en) 1991-06-07
NZ228285A (en) 1991-08-27
DK116789D0 (da) 1989-03-10
ES2078222T3 (es) 1995-12-16
CZ278971B6 (en) 1994-11-16
NO891007L (no) 1989-09-12
DE332222T1 (de) 1990-03-22
EP0332222A2 (en) 1989-09-13
KR0138658B1 (ko) 1998-05-15
DK116789A (da) 1989-11-28
JPH01294632A (ja) 1989-11-28
AU3125389A (en) 1989-09-14
CZ149089A3 (en) 1994-03-16
CA1336676C (en) 1995-08-15
KR890014131A (ko) 1989-10-21
EP0332222A3 (en) 1991-03-06
DE68924491D1 (de) 1995-11-16
NO179479B (no) 1996-07-08
US5840685A (en) 1998-11-24
JP2801249B2 (ja) 1998-09-21
NO891007D0 (no) 1989-03-09

Similar Documents

Publication Publication Date Title
NO179479C (no) Fremgangsmåte for fremstilling av et intravaginalt farmasöytisk preparat
NO178687C (no) Fremgangsmåte for fremstilling av forenlige, lagringsstabile erythropoietinpreparater
ES541521A0 (es) Un procedimiento para la preparacion de piridazinaminas.
FI874706A0 (fi) Menetelmä glykosyloimattoman yhdistelmäinterferoni- :n stabiilien, farmaseuttisten koostumusten valmistamiseksi
DE69329651D1 (de) Wässrige arzneizusammensetzung, welche das menschliche wachstumshormon enthält
ATE203411T1 (de) Lagerstabile wässrige pharmazeutische zubereitungen von g-csf
DE68918853D1 (de) Formulierung von menschlichen wachstumshormonen.
EP0233013A3 (en) Modified enzyme
IL90056A (en) Topical pharmaceutical compositions containing 4-quinoline carboxylic acid derivatives
HUT66238A (en) Bicyclic carboxylic acid derivatives, pharmaceutical compositions contg. them as active agent and process to prepare them
MX9302509A (es) Composiciones de polipeptidos estables en almacenamiento y metodo para su preparacion.
FR2684878B1 (fr) Composition pharmaceutique stabilisee d'il2 humaine recombinante non glycosylee sous forme reduite et son procede de preparation.
EP0056681A3 (en) Levonantradol and n-methyllevonantradol formulations
ATE187077T1 (de) Wässrige zubereitung mit verzögerter wirkstofffreigabe
KR950701347A (ko) 신규한 향종양성 사이토킨(A novel anti-neoplastic cytokine)
JPS52120192A (en) Preparation of prostaglandin
JPS643161A (en) (2-cyano-2-oxyiminoacetyl)-amino acid derivative
JPS54132221A (en) Water-based medicine for vaginal administration