NO178109C - N-alkyl-3-fenyl-3-(2-alkylthiofenoksy)propylaminer og en farmasöytisk formulering - Google Patents

N-alkyl-3-fenyl-3-(2-alkylthiofenoksy)propylaminer og en farmasöytisk formulering

Info

Publication number
NO178109C
NO178109C NO923710A NO923710A NO178109C NO 178109 C NO178109 C NO 178109C NO 923710 A NO923710 A NO 923710A NO 923710 A NO923710 A NO 923710A NO 178109 C NO178109 C NO 178109C
Authority
NO
Norway
Prior art keywords
propylamines
phenyl
alkyl
alkylthiophenoxy
pharmaceutical formulation
Prior art date
Application number
NO923710A
Other languages
English (en)
Norwegian (no)
Other versions
NO178109B (no
NO923710L (no
NO923710D0 (no
Inventor
Donald Richard Gehlert
David Wayne Robertson
David Taiwai Wong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO923710D0 publication Critical patent/NO923710D0/no
Publication of NO923710L publication Critical patent/NO923710L/no
Publication of NO178109B publication Critical patent/NO178109B/no
Publication of NO178109C publication Critical patent/NO178109C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/29—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
NO923710A 1991-09-27 1992-09-24 N-alkyl-3-fenyl-3-(2-alkylthiofenoksy)propylaminer og en farmasöytisk formulering NO178109C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/766,993 US5281624A (en) 1991-09-27 1991-09-27 N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof

Publications (4)

Publication Number Publication Date
NO923710D0 NO923710D0 (no) 1992-09-24
NO923710L NO923710L (no) 1993-03-29
NO178109B NO178109B (no) 1995-10-16
NO178109C true NO178109C (no) 1996-01-24

Family

ID=25078150

Family Applications (1)

Application Number Title Priority Date Filing Date
NO923710A NO178109C (no) 1991-09-27 1992-09-24 N-alkyl-3-fenyl-3-(2-alkylthiofenoksy)propylaminer og en farmasöytisk formulering

Country Status (23)

Country Link
US (1) US5281624A (OSRAM)
EP (1) EP0534756A3 (OSRAM)
JP (2) JP3256291B2 (OSRAM)
KR (1) KR100221180B1 (OSRAM)
CN (1) CN1033580C (OSRAM)
AT (1) ATE124934T1 (OSRAM)
AU (1) AU655075B2 (OSRAM)
BR (2) BR9203743A (OSRAM)
CA (2) CA2079161C (OSRAM)
CZ (1) CZ281817B6 (OSRAM)
DE (1) DE69203424T2 (OSRAM)
FI (1) FI111250B (OSRAM)
HU (1) HU215519B (OSRAM)
IL (1) IL103277A (OSRAM)
MX (1) MX9205433A (OSRAM)
MY (1) MY108304A (OSRAM)
NO (1) NO178109C (OSRAM)
NZ (1) NZ244460A (OSRAM)
RU (1) RU2057120C1 (OSRAM)
SK (1) SK290892A3 (OSRAM)
TW (1) TW249225B (OSRAM)
YU (1) YU87192A (OSRAM)
ZA (1) ZA927240B (OSRAM)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071970A (en) * 1993-02-08 2000-06-06 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US7087765B2 (en) * 1995-06-07 2006-08-08 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
US6017965A (en) * 1993-02-08 2000-01-25 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
TW344661B (en) * 1993-11-24 1998-11-11 Lilly Co Eli Pharmaceutical composition for treatment of incontinence
KR19990035817A (ko) * 1995-07-24 1999-05-25 피터 지. 스트링거 주의력 결핍증/활동항진증의 치료 방법
JP2001502302A (ja) * 1996-09-19 2001-02-20 アメリカン・ホーム・プロダクツ・コーポレイション 尿失禁を治療する方法
DK1069900T3 (da) * 1998-04-09 2005-10-31 Pharmacia & Upjohn Co Llc Anvendelse af reboxetin til behandling af neuropsykiatriske lidelser
US6586427B2 (en) 1998-04-09 2003-07-01 Pharmacia & Upjohn Company Treatments for nervous disorders
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
PL350924A1 (en) * 1999-04-06 2003-02-10 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
KR100882544B1 (ko) 1999-05-24 2009-02-12 미쓰비시 타나베 파마 코퍼레이션 페녹시프로필아민 화합물
WO2001001973A2 (en) * 1999-07-01 2001-01-11 Pharmacia & Upjohn Company Highly selective norepinephrine reuptake inhibitors and methods of using the same
US20040034106A1 (en) * 2001-11-06 2004-02-19 Read Holly Ann Treatment of anxiety disorders
ATE365035T1 (de) * 2001-11-30 2007-07-15 Lilly Co Eli Verwendung von norepinephrinwiederaufnahmehemmern zur behandlung von ticks
EP1458368B1 (en) * 2001-12-11 2007-11-21 Eli Lilly And Company Use of norepinephrine reuptake inhibitors for the treatment of cognitive failure
EP1539181B1 (en) * 2003-04-04 2007-06-27 Dynogen Pharmaceuticals Inc. Method of treating lower urinary tract disorders
WO2005020976A2 (en) * 2003-08-27 2005-03-10 Eli Lilly And Company Treatment of pervasive developmental disorders with norepinephrine reuptake inhibitors
KR20060121178A (ko) * 2003-12-12 2006-11-28 일라이 릴리 앤드 캄파니 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제
ITMI20061987A1 (it) * 2006-10-16 2008-04-17 Archimica Srl Processo per la sintesi di arilossipropilammine ed eteroarilossipropilammine.
JP2020536941A (ja) * 2017-10-16 2020-12-17 エステベ ファーマシューティカルズ, ソシエダッド アノニマEsteve Pharmaceuticals, S.A. 疼痛及び疼痛に関連する状態を治療するためのプロパンアミン誘導体
CN113121394B (zh) * 2019-12-30 2022-11-08 中国药科大学 一种苯氧乙酸类衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018895A (en) * 1974-01-10 1977-04-19 Eli Lilly And Company Aryloxyphenylpropylamines in treating depression
US4313896A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Aryloxyphenylpropylamines
US4194009A (en) * 1974-01-10 1980-03-18 Eli Lilly And Company Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4626549A (en) * 1974-01-10 1986-12-02 Eli Lilly And Company Treatment of obesity with aryloxyphenylpropylamines
US4584404A (en) * 1974-01-10 1986-04-22 Eli Lilly And Company Substituted phenoxyphenylproply dimethylamines
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
CA1337128C (en) * 1988-04-08 1995-09-26 David Wayne Robertson Propanamine derivatives

Also Published As

Publication number Publication date
NZ244460A (en) 1994-10-26
DE69203424T2 (de) 1996-01-11
CZ290892A3 (en) 1993-04-14
HU9203051D0 (en) 1992-12-28
HUT65375A (en) 1994-05-02
NO178109B (no) 1995-10-16
CA2079162A1 (en) 1993-03-28
CN1071416A (zh) 1993-04-28
KR100221180B1 (ko) 1999-09-15
BR9203743A (pt) 1993-04-20
DE69203424D1 (de) 1995-08-17
FI111250B (fi) 2003-06-30
CZ281817B6 (cs) 1997-02-12
AU655075B2 (en) 1994-12-01
ATE124934T1 (de) 1995-07-15
YU87192A (sh) 1995-10-24
IL103277A0 (en) 1993-02-21
MY108304A (en) 1996-09-30
JPH05238996A (ja) 1993-09-17
CA2079161A1 (en) 1993-03-28
RU2057120C1 (ru) 1996-03-27
FI924305L (fi) 1993-03-28
JP3256291B2 (ja) 2002-02-12
JPH05201961A (ja) 1993-08-10
AU2537092A (en) 1993-04-01
FI924305A0 (fi) 1992-09-25
MX9205433A (es) 1993-03-01
US5281624A (en) 1994-01-25
NO923710L (no) 1993-03-29
CA2079161C (en) 2004-02-17
NO923710D0 (no) 1992-09-24
EP0534756A2 (en) 1993-03-31
SK280480B6 (sk) 2000-02-14
CN1033580C (zh) 1996-12-18
ZA927240B (en) 1994-03-22
IL103277A (en) 1997-11-20
HU215519B (hu) 1999-01-28
TW249225B (OSRAM) 1995-06-11
KR930005972A (ko) 1993-04-20
SK290892A3 (en) 2000-02-14
BR1100384A (pt) 1999-08-31
EP0534756A3 (en) 1993-06-16

Similar Documents

Publication Publication Date Title
NO178109C (no) N-alkyl-3-fenyl-3-(2-alkylthiofenoksy)propylaminer og en farmasöytisk formulering
ES2082887T3 (es) Flupirtina en combinacion con antiparkinsonianos para combatir espasmos musculares.
BR9404842A (pt) Compostos,processo para sua preparação e formulação farmacêutica
DK376188A (da) Farmaceutisk dosisenhed
MX9201993A (es) Procedimiento para la obtencion de elastomeros de poliurea que presentan grupos uretano.
ES520218A0 (es) Un procedimiento para la preparacion de nuevos 2,3-diaril-5-halotiofenos.
PT656209E (pt) Derivados de melatonina para uso no tratamento de perturbacoes de dessincronizacao
DK561589A (da) Flydende oralt farmaceutisk praeparat
SE8900875L (sv) Osteoporosbehandling
DK78788A (da) 4-substituerede benzamid-derivater og farmaceutiske midler indeholdende saadanne derivater
NO882559D0 (no) Transdermalt leveringssystem for farmasoeytiske forbindelser.
GR3034661T3 (en) Use of Selegiline in vetenary medicine.
DK0778028T3 (da) Præparater til forebyggelse og behandling af urogenitale lidelser, der indeholder bismuth og ét eller flere antimikrobielle midler
DK0486586T3 (da) Kynurensyrederivater, fremstilling deraf og farmaceutiske præparater, der indeholder dem
ES2077358T3 (es) N-alquil-3-fenil-3-(2-alquiltiofenoxi)propilaminas.
ES2192219T3 (es) Composiciones para la prevencion y tratamiento de trastornos urogenitales, que contienen bismuto.
ES1003433Y (es) Almohadilla transportable perfeccionada para usos diversos.
ES1003442Y (es) Dispositivo traccionador para miembros fracturados.
IT8520565A0 (it) Dispositivo per massaggiare estremita', per esempio gambe.