ES520218A0 - Un procedimiento para la preparacion de nuevos 2,3-diaril-5-halotiofenos. - Google Patents
Un procedimiento para la preparacion de nuevos 2,3-diaril-5-halotiofenos.Info
- Publication number
- ES520218A0 ES520218A0 ES520218A ES520218A ES520218A0 ES 520218 A0 ES520218 A0 ES 520218A0 ES 520218 A ES520218 A ES 520218A ES 520218 A ES520218 A ES 520218A ES 520218 A0 ES520218 A0 ES 520218A0
- Authority
- ES
- Spain
- Prior art keywords
- halotiofen
- diaril
- procedure
- preparation
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35430082A | 1982-03-03 | 1982-03-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8403884A1 ES8403884A1 (es) | 1984-04-01 |
ES520218A0 true ES520218A0 (es) | 1984-04-01 |
Family
ID=23392697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES520218A Granted ES520218A0 (es) | 1982-03-03 | 1983-03-02 | Un procedimiento para la preparacion de nuevos 2,3-diaril-5-halotiofenos. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0087629B1 (es) |
JP (1) | JPS58159489A (es) |
AT (1) | ATE17480T1 (es) |
AU (1) | AU553269B2 (es) |
CA (1) | CA1242725A (es) |
DE (1) | DE3361812D1 (es) |
DK (1) | DK161320C (es) |
ES (1) | ES520218A0 (es) |
FI (1) | FI79308C (es) |
GR (1) | GR78135B (es) |
IE (1) | IE54816B1 (es) |
IL (1) | IL67940A (es) |
NO (1) | NO155198B (es) |
NZ (1) | NZ203317A (es) |
PH (1) | PH18061A (es) |
PT (1) | PT76247B (es) |
SU (1) | SU1250172A3 (es) |
ZA (1) | ZA831046B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3346175A1 (de) * | 1983-12-21 | 1985-07-11 | Merck Patent Gmbh, 6100 Darmstadt | Pyridylthiophene |
NZ211146A (en) * | 1984-02-29 | 1987-10-30 | Merck & Co Inc | 2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions |
US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
GB9012936D0 (en) * | 1990-06-11 | 1990-08-01 | Fujisawa Pharmaceutical Co | Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
US6492413B2 (en) | 1993-01-15 | 2002-12-10 | G.D. Searle & Co. | 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
WO1994015932A1 (en) * | 1993-01-15 | 1994-07-21 | G.D. Searle & Co. | Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
GB9420616D0 (en) * | 1994-10-12 | 1994-11-30 | Merck Sharp & Dohme | Method, compositions and use |
AU6718494A (en) * | 1993-05-13 | 1994-12-12 | Merck Frosst Canada Inc. | 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase |
US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
US5840746A (en) * | 1993-06-24 | 1998-11-24 | Merck Frosst Canada, Inc. | Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases |
DE10001166A1 (de) | 2000-01-13 | 2001-07-19 | Merckle Gmbh | Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung |
AUPR283801A0 (en) * | 2001-02-01 | 2001-03-01 | Australian National University, The | Chemical compounds and methods |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6028837B2 (ja) * | 1979-08-09 | 1985-07-06 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | ジアリ−ルチオフエン化合物、その製造法およびそれを含有する抗炎症剤 |
US4302461A (en) * | 1979-08-09 | 1981-11-24 | E. I. Du Pont De Nemours And Company | Antiinflammatory 5-substituted-2,3-diarylthiophenes |
US4381311A (en) * | 1980-12-29 | 1983-04-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols |
-
1983
- 1983-02-10 AT AT83101247T patent/ATE17480T1/de active
- 1983-02-10 DE DE8383101247T patent/DE3361812D1/de not_active Expired
- 1983-02-10 EP EP83101247A patent/EP0087629B1/en not_active Expired
- 1983-02-10 CA CA000421318A patent/CA1242725A/en not_active Expired
- 1983-02-16 JP JP58022957A patent/JPS58159489A/ja active Granted
- 1983-02-16 FI FI830523A patent/FI79308C/fi not_active IP Right Cessation
- 1983-02-16 PT PT76247A patent/PT76247B/pt not_active IP Right Cessation
- 1983-02-16 AU AU11460/83A patent/AU553269B2/en not_active Ceased
- 1983-02-16 GR GR70528A patent/GR78135B/el unknown
- 1983-02-16 DK DK067683A patent/DK161320C/da not_active IP Right Cessation
- 1983-02-16 PH PH28522A patent/PH18061A/en unknown
- 1983-02-16 NO NO830527A patent/NO155198B/no unknown
- 1983-02-16 SU SU833552852A patent/SU1250172A3/ru active
- 1983-02-16 ZA ZA831046A patent/ZA831046B/xx unknown
- 1983-02-17 NZ NZ203317A patent/NZ203317A/en unknown
- 1983-02-17 IE IE331/83A patent/IE54816B1/en not_active IP Right Cessation
- 1983-02-17 IL IL67940A patent/IL67940A/xx not_active IP Right Cessation
- 1983-03-02 ES ES520218A patent/ES520218A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
DK161320C (da) | 1991-12-09 |
NO830527L (no) | 1983-09-05 |
SU1250172A3 (ru) | 1986-08-07 |
NO155198B (no) | 1986-11-17 |
IL67940A (en) | 1986-02-28 |
CA1242725A (en) | 1988-10-04 |
PH18061A (en) | 1985-03-18 |
ZA831046B (en) | 1984-09-26 |
EP0087629B1 (en) | 1986-01-15 |
ATE17480T1 (de) | 1986-02-15 |
DK161320B (da) | 1991-06-24 |
DK67683D0 (da) | 1983-02-16 |
PT76247B (en) | 1986-02-04 |
IE54816B1 (en) | 1990-02-14 |
ES8403884A1 (es) | 1984-04-01 |
EP0087629A2 (en) | 1983-09-07 |
EP0087629A3 (en) | 1983-10-19 |
FI830523L (fi) | 1983-09-04 |
JPH0314312B2 (es) | 1991-02-26 |
GR78135B (es) | 1984-09-26 |
IE830331L (en) | 1983-09-03 |
PT76247A (en) | 1983-03-01 |
AU553269B2 (en) | 1986-07-10 |
DK67683A (da) | 1983-09-04 |
FI79308C (fi) | 1989-12-11 |
DE3361812D1 (en) | 1986-02-27 |
AU1146083A (en) | 1983-09-08 |
FI830523A0 (fi) | 1983-02-16 |
NZ203317A (en) | 1985-07-12 |
JPS58159489A (ja) | 1983-09-21 |
IL67940A0 (en) | 1983-06-15 |
FI79308B (fi) | 1989-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000503 |