DK161320C - Analogifremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thiophener - Google Patents
Analogifremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thiophenerInfo
- Publication number
- DK161320C DK161320C DK067683A DK67683A DK161320C DK 161320 C DK161320 C DK 161320C DK 067683 A DK067683 A DK 067683A DK 67683 A DK67683 A DK 67683A DK 161320 C DK161320 C DK 161320C
- Authority
- DK
- Denmark
- Prior art keywords
- diaryl
- thiophenes
- halogen
- preparation
- analogy procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Measuring Volume Flow (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35430082A | 1982-03-03 | 1982-03-03 | |
| US35430082 | 1982-03-03 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK67683D0 DK67683D0 (da) | 1983-02-16 |
| DK67683A DK67683A (da) | 1983-09-04 |
| DK161320B DK161320B (da) | 1991-06-24 |
| DK161320C true DK161320C (da) | 1991-12-09 |
Family
ID=23392697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK067683A DK161320C (da) | 1982-03-03 | 1983-02-16 | Analogifremgangsmaade til fremstilling af 2,3-diaryl-5-halogen-thiophener |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0087629B1 (da) |
| JP (1) | JPS58159489A (da) |
| AT (1) | ATE17480T1 (da) |
| AU (1) | AU553269B2 (da) |
| CA (1) | CA1242725A (da) |
| DE (1) | DE3361812D1 (da) |
| DK (1) | DK161320C (da) |
| ES (1) | ES8403884A1 (da) |
| FI (1) | FI79308C (da) |
| GR (1) | GR78135B (da) |
| IE (1) | IE54816B1 (da) |
| IL (1) | IL67940A (da) |
| NO (1) | NO155198B (da) |
| NZ (1) | NZ203317A (da) |
| PH (1) | PH18061A (da) |
| PT (1) | PT76247B (da) |
| SU (1) | SU1250172A3 (da) |
| ZA (1) | ZA831046B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346175A1 (de) * | 1983-12-21 | 1985-07-11 | Merck Patent Gmbh, 6100 Darmstadt | Pyridylthiophene |
| NZ211146A (en) * | 1984-02-29 | 1987-10-30 | Merck & Co Inc | 2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions |
| US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
| GB9012936D0 (en) * | 1990-06-11 | 1990-08-01 | Fujisawa Pharmaceutical Co | Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| US6492413B2 (en) | 1993-01-15 | 2002-12-10 | G.D. Searle & Co. | 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
| DE69406903T2 (de) * | 1993-01-15 | 1998-04-09 | Searle & Co | 3,4-diarylthiophene und analoga davon, sowie deren verwendung als entzündungshemmende mittel |
| GB9420616D0 (en) * | 1994-10-12 | 1994-11-30 | Merck Sharp & Dohme | Method, compositions and use |
| AU6718494A (en) * | 1993-05-13 | 1994-12-12 | Merck Frosst Canada Inc. | 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase |
| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5840746A (en) * | 1993-06-24 | 1998-11-24 | Merck Frosst Canada, Inc. | Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases |
| DE10001166A1 (de) | 2000-01-13 | 2001-07-19 | Merckle Gmbh | Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung |
| AUPR283801A0 (en) * | 2001-02-01 | 2001-03-01 | Australian National University, The | Chemical compounds and methods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4302461A (en) * | 1979-08-09 | 1981-11-24 | E. I. Du Pont De Nemours And Company | Antiinflammatory 5-substituted-2,3-diarylthiophenes |
| JPS6028837B2 (ja) * | 1979-08-09 | 1985-07-06 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | ジアリ−ルチオフエン化合物、その製造法およびそれを含有する抗炎症剤 |
| US4381311A (en) * | 1980-12-29 | 1983-04-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols |
-
1983
- 1983-02-10 DE DE8383101247T patent/DE3361812D1/de not_active Expired
- 1983-02-10 EP EP83101247A patent/EP0087629B1/en not_active Expired
- 1983-02-10 CA CA000421318A patent/CA1242725A/en not_active Expired
- 1983-02-10 AT AT83101247T patent/ATE17480T1/de active
- 1983-02-16 ZA ZA831046A patent/ZA831046B/xx unknown
- 1983-02-16 FI FI830523A patent/FI79308C/fi not_active IP Right Cessation
- 1983-02-16 JP JP58022957A patent/JPS58159489A/ja active Granted
- 1983-02-16 AU AU11460/83A patent/AU553269B2/en not_active Ceased
- 1983-02-16 GR GR70528A patent/GR78135B/el unknown
- 1983-02-16 SU SU833552852A patent/SU1250172A3/ru active
- 1983-02-16 NO NO830527A patent/NO155198B/no unknown
- 1983-02-16 DK DK067683A patent/DK161320C/da not_active IP Right Cessation
- 1983-02-16 PT PT76247A patent/PT76247B/pt not_active IP Right Cessation
- 1983-02-16 PH PH28522A patent/PH18061A/en unknown
- 1983-02-17 IE IE331/83A patent/IE54816B1/en not_active IP Right Cessation
- 1983-02-17 NZ NZ203317A patent/NZ203317A/en unknown
- 1983-02-17 IL IL67940A patent/IL67940A/xx not_active IP Right Cessation
- 1983-03-02 ES ES520218A patent/ES8403884A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3361812D1 (en) | 1986-02-27 |
| CA1242725A (en) | 1988-10-04 |
| FI830523L (fi) | 1983-09-04 |
| AU553269B2 (en) | 1986-07-10 |
| IL67940A0 (en) | 1983-06-15 |
| PT76247B (en) | 1986-02-04 |
| IL67940A (en) | 1986-02-28 |
| EP0087629B1 (en) | 1986-01-15 |
| DK67683D0 (da) | 1983-02-16 |
| AU1146083A (en) | 1983-09-08 |
| FI830523A0 (fi) | 1983-02-16 |
| IE54816B1 (en) | 1990-02-14 |
| IE830331L (en) | 1983-09-03 |
| EP0087629A3 (en) | 1983-10-19 |
| SU1250172A3 (ru) | 1986-08-07 |
| ZA831046B (en) | 1984-09-26 |
| JPH0314312B2 (da) | 1991-02-26 |
| NO155198B (no) | 1986-11-17 |
| NO830527L (no) | 1983-09-05 |
| ATE17480T1 (de) | 1986-02-15 |
| DK161320B (da) | 1991-06-24 |
| DK67683A (da) | 1983-09-04 |
| EP0087629A2 (en) | 1983-09-07 |
| FI79308B (fi) | 1989-08-31 |
| NZ203317A (en) | 1985-07-12 |
| ES520218A0 (es) | 1984-04-01 |
| FI79308C (fi) | 1989-12-11 |
| ES8403884A1 (es) | 1984-04-01 |
| PH18061A (en) | 1985-03-18 |
| GR78135B (da) | 1984-09-26 |
| JPS58159489A (ja) | 1983-09-21 |
| PT76247A (en) | 1983-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |