ZA831046B - Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes - Google Patents
Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenesInfo
- Publication number
- ZA831046B ZA831046B ZA831046A ZA831046A ZA831046B ZA 831046 B ZA831046 B ZA 831046B ZA 831046 A ZA831046 A ZA 831046A ZA 831046 A ZA831046 A ZA 831046A ZA 831046 B ZA831046 B ZA 831046B
- Authority
- ZA
- South Africa
- Prior art keywords
- diaryl
- antiinflammatory
- analgesic
- thiophenes
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Measuring Volume Flow (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35430082A | 1982-03-03 | 1982-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA831046B true ZA831046B (en) | 1984-09-26 |
Family
ID=23392697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA831046A ZA831046B (en) | 1982-03-03 | 1983-02-16 | Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0087629B1 (es) |
| JP (1) | JPS58159489A (es) |
| AT (1) | ATE17480T1 (es) |
| AU (1) | AU553269B2 (es) |
| CA (1) | CA1242725A (es) |
| DE (1) | DE3361812D1 (es) |
| DK (1) | DK161320C (es) |
| ES (1) | ES8403884A1 (es) |
| FI (1) | FI79308C (es) |
| GR (1) | GR78135B (es) |
| IE (1) | IE54816B1 (es) |
| IL (1) | IL67940A (es) |
| NO (1) | NO155198B (es) |
| NZ (1) | NZ203317A (es) |
| PH (1) | PH18061A (es) |
| PT (1) | PT76247B (es) |
| SU (1) | SU1250172A3 (es) |
| ZA (1) | ZA831046B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346175A1 (de) * | 1983-12-21 | 1985-07-11 | Merck Patent Gmbh, 6100 Darmstadt | Pyridylthiophene |
| NZ211146A (en) * | 1984-02-29 | 1987-10-30 | Merck & Co Inc | 2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions |
| US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
| GB9012936D0 (en) * | 1990-06-11 | 1990-08-01 | Fujisawa Pharmaceutical Co | Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| US6492413B2 (en) | 1993-01-15 | 2002-12-10 | G.D. Searle & Co. | 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
| ES2111288T3 (es) * | 1993-01-15 | 1998-03-01 | Searle & Co | Nuevos 3,4-diaril tiofenos y analogos de los mismos utiles como agentes antiinflamatorios. |
| GB9420616D0 (en) * | 1994-10-12 | 1994-11-30 | Merck Sharp & Dohme | Method, compositions and use |
| CA2161789A1 (en) * | 1993-05-13 | 1994-11-24 | Jacques Yves Gauthier | 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase |
| US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5840746A (en) * | 1993-06-24 | 1998-11-24 | Merck Frosst Canada, Inc. | Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases |
| DE10001166A1 (de) | 2000-01-13 | 2001-07-19 | Merckle Gmbh | Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung |
| AUPR283801A0 (en) * | 2001-02-01 | 2001-03-01 | Australian National University, The | Chemical compounds and methods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4302461A (en) * | 1979-08-09 | 1981-11-24 | E. I. Du Pont De Nemours And Company | Antiinflammatory 5-substituted-2,3-diarylthiophenes |
| JPS6028837B2 (ja) * | 1979-08-09 | 1985-07-06 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | ジアリ−ルチオフエン化合物、その製造法およびそれを含有する抗炎症剤 |
| US4381311A (en) * | 1980-12-29 | 1983-04-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols |
-
1983
- 1983-02-10 DE DE8383101247T patent/DE3361812D1/de not_active Expired
- 1983-02-10 AT AT83101247T patent/ATE17480T1/de active
- 1983-02-10 EP EP83101247A patent/EP0087629B1/en not_active Expired
- 1983-02-10 CA CA000421318A patent/CA1242725A/en not_active Expired
- 1983-02-16 JP JP58022957A patent/JPS58159489A/ja active Granted
- 1983-02-16 DK DK067683A patent/DK161320C/da not_active IP Right Cessation
- 1983-02-16 AU AU11460/83A patent/AU553269B2/en not_active Ceased
- 1983-02-16 GR GR70528A patent/GR78135B/el unknown
- 1983-02-16 FI FI830523A patent/FI79308C/fi not_active IP Right Cessation
- 1983-02-16 SU SU833552852A patent/SU1250172A3/ru active
- 1983-02-16 PT PT76247A patent/PT76247B/pt not_active IP Right Cessation
- 1983-02-16 NO NO830527A patent/NO155198B/no unknown
- 1983-02-16 PH PH28522A patent/PH18061A/en unknown
- 1983-02-16 ZA ZA831046A patent/ZA831046B/xx unknown
- 1983-02-17 IE IE331/83A patent/IE54816B1/en not_active IP Right Cessation
- 1983-02-17 IL IL67940A patent/IL67940A/xx not_active IP Right Cessation
- 1983-02-17 NZ NZ203317A patent/NZ203317A/en unknown
- 1983-03-02 ES ES520218A patent/ES8403884A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58159489A (ja) | 1983-09-21 |
| ES520218A0 (es) | 1984-04-01 |
| DK67683D0 (da) | 1983-02-16 |
| FI79308C (fi) | 1989-12-11 |
| DE3361812D1 (en) | 1986-02-27 |
| EP0087629A3 (en) | 1983-10-19 |
| FI830523A0 (fi) | 1983-02-16 |
| JPH0314312B2 (es) | 1991-02-26 |
| ATE17480T1 (de) | 1986-02-15 |
| NZ203317A (en) | 1985-07-12 |
| EP0087629A2 (en) | 1983-09-07 |
| SU1250172A3 (ru) | 1986-08-07 |
| GR78135B (es) | 1984-09-26 |
| IL67940A (en) | 1986-02-28 |
| FI79308B (fi) | 1989-08-31 |
| IL67940A0 (en) | 1983-06-15 |
| CA1242725A (en) | 1988-10-04 |
| NO830527L (no) | 1983-09-05 |
| DK161320B (da) | 1991-06-24 |
| PT76247A (en) | 1983-03-01 |
| EP0087629B1 (en) | 1986-01-15 |
| FI830523L (fi) | 1983-09-04 |
| DK67683A (da) | 1983-09-04 |
| NO155198B (no) | 1986-11-17 |
| DK161320C (da) | 1991-12-09 |
| IE830331L (en) | 1983-09-03 |
| IE54816B1 (en) | 1990-02-14 |
| PT76247B (en) | 1986-02-04 |
| AU1146083A (en) | 1983-09-08 |
| AU553269B2 (en) | 1986-07-10 |
| ES8403884A1 (es) | 1984-04-01 |
| PH18061A (en) | 1985-03-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5791915A (en) | Novel lipid composition useful for dietetics, resuscitation and treatment | |
| NO861793L (no) | Vaeskebehandlings-prosess og -utstyr. | |
| EP0204597A3 (en) | Use of alfuzosine in the treatment of urinary affections | |
| DE3362317D1 (en) | Antiinflammatory and analgesic gel | |
| ES8302652A2 (es) | Un procedimiento para la preparacion de derivados de pirrol | |
| DE3361812D1 (en) | Antiinflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes | |
| ZA87884B (en) | Therapeutic agent | |
| AU530790B2 (en) | Triazinones and their use in treating gastrointestinal disorders | |
| DE3279834D1 (en) | 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression | |
| ES8800048A1 (es) | Mejoras introducidas en un procedimiento para la preparacion de piroxicam o una sal farmaceuticamente aceptable del mismo en forma de composicion anti-inflamatoria mejorada. | |
| ZA849576B (en) | 1,7-diphenyl-3-methyllaza-7-cyano-8-methylnonane for use in the treatment of diseases | |
| JPS5595926A (en) | Treating contact lens and treatment composition | |
| NO834302L (no) | Uavhengig loepe- og sporrulle-loepeverk | |
| ES8507552A1 (es) | Un procedimiento para preparar 6-metilsulfonil-espiro-(croman-4,4'-imidazolidin)-2',5'-diona | |
| JPS56139485A (en) | 4-alpha-cycloamino-arylmethyl-6-methyl- 1,3-dihydro-flo(3,4-c)-pyridine-7-ol, manufacture and use | |
| JPS57134416A (en) | Acne treatment and therapeutical composition | |
| IL60607A0 (en) | Material for magnetotherapy and appliances for medical treatment based on the proposed material | |
| ZA879420B (en) | 5-aryl-3h-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders | |
| PH18354A (en) | The production and treatment of ferrochromium |