PH18061A - Anti-inflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes - Google Patents
Anti-inflammatory and/or analgesic 2,3-diaryl-5-halo thiophenesInfo
- Publication number
- PH18061A PH18061A PH28522A PH28522A PH18061A PH 18061 A PH18061 A PH 18061A PH 28522 A PH28522 A PH 28522A PH 28522 A PH28522 A PH 28522A PH 18061 A PH18061 A PH 18061A
- Authority
- PH
- Philippines
- Prior art keywords
- diaryl
- analgesic
- inflammatory
- thiophenes
- halo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Photoreceptors In Electrophotography (AREA)
- Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
- Measuring Volume Flow (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35430082A | 1982-03-03 | 1982-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH18061A true PH18061A (en) | 1985-03-18 |
Family
ID=23392697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH28522A PH18061A (en) | 1982-03-03 | 1983-02-16 | Anti-inflammatory and/or analgesic 2,3-diaryl-5-halo thiophenes |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0087629B1 (es) |
| JP (1) | JPS58159489A (es) |
| AT (1) | ATE17480T1 (es) |
| AU (1) | AU553269B2 (es) |
| CA (1) | CA1242725A (es) |
| DE (1) | DE3361812D1 (es) |
| DK (1) | DK161320C (es) |
| ES (1) | ES8403884A1 (es) |
| FI (1) | FI79308C (es) |
| GR (1) | GR78135B (es) |
| IE (1) | IE54816B1 (es) |
| IL (1) | IL67940A (es) |
| NO (1) | NO155198B (es) |
| NZ (1) | NZ203317A (es) |
| PH (1) | PH18061A (es) |
| PT (1) | PT76247B (es) |
| SU (1) | SU1250172A3 (es) |
| ZA (1) | ZA831046B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346175A1 (de) * | 1983-12-21 | 1985-07-11 | Merck Patent Gmbh, 6100 Darmstadt | Pyridylthiophene |
| NZ211146A (en) * | 1984-02-29 | 1987-10-30 | Merck & Co Inc | 2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions |
| GB9012936D0 (en) * | 1990-06-11 | 1990-08-01 | Fujisawa Pharmaceutical Co | Thiophene derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| US5571810A (en) * | 1990-06-11 | 1996-11-05 | Fujisawa Pharmaceutical Co., Ltd. | Thiophene derivatives |
| US6492413B2 (en) | 1993-01-15 | 2002-12-10 | G.D. Searle & Co. | 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
| CA2152792C (en) * | 1993-01-15 | 2000-02-15 | Stephen R. Bertenshaw | Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
| GB9420616D0 (en) * | 1994-10-12 | 1994-11-30 | Merck Sharp & Dohme | Method, compositions and use |
| WO1994026731A1 (en) * | 1993-05-13 | 1994-11-24 | Merck Frosst Canada Inc. | 2-substituted-3,4-diarylthiophene derivatives as inhibitors of cyclooxygenase |
| US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5840746A (en) * | 1993-06-24 | 1998-11-24 | Merck Frosst Canada, Inc. | Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases |
| DE10001166A1 (de) | 2000-01-13 | 2001-07-19 | Merckle Gmbh | Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung |
| AUPR283801A0 (en) * | 2001-02-01 | 2001-03-01 | Australian National University, The | Chemical compounds and methods |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4302461A (en) * | 1979-08-09 | 1981-11-24 | E. I. Du Pont De Nemours And Company | Antiinflammatory 5-substituted-2,3-diarylthiophenes |
| JPS6028837B2 (ja) * | 1979-08-09 | 1985-07-06 | イ−・アイ・デユポン・ド・ネモア−ス・アンド・コンパニ− | ジアリ−ルチオフエン化合物、その製造法およびそれを含有する抗炎症剤 |
| US4381311A (en) * | 1980-12-29 | 1983-04-26 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-α-(polyhalomethyl)-2-thiophenemethanols |
-
1983
- 1983-02-10 DE DE8383101247T patent/DE3361812D1/de not_active Expired
- 1983-02-10 EP EP83101247A patent/EP0087629B1/en not_active Expired
- 1983-02-10 AT AT83101247T patent/ATE17480T1/de active
- 1983-02-10 CA CA000421318A patent/CA1242725A/en not_active Expired
- 1983-02-16 NO NO830527A patent/NO155198B/no unknown
- 1983-02-16 GR GR70528A patent/GR78135B/el unknown
- 1983-02-16 AU AU11460/83A patent/AU553269B2/en not_active Ceased
- 1983-02-16 ZA ZA831046A patent/ZA831046B/xx unknown
- 1983-02-16 PT PT76247A patent/PT76247B/pt not_active IP Right Cessation
- 1983-02-16 SU SU833552852A patent/SU1250172A3/ru active
- 1983-02-16 FI FI830523A patent/FI79308C/fi not_active IP Right Cessation
- 1983-02-16 JP JP58022957A patent/JPS58159489A/ja active Granted
- 1983-02-16 PH PH28522A patent/PH18061A/en unknown
- 1983-02-16 DK DK067683A patent/DK161320C/da not_active IP Right Cessation
- 1983-02-17 IL IL67940A patent/IL67940A/xx not_active IP Right Cessation
- 1983-02-17 IE IE331/83A patent/IE54816B1/en not_active IP Right Cessation
- 1983-02-17 NZ NZ203317A patent/NZ203317A/en unknown
- 1983-03-02 ES ES520218A patent/ES8403884A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IE830331L (en) | 1983-09-03 |
| FI79308C (fi) | 1989-12-11 |
| DK67683A (da) | 1983-09-04 |
| IL67940A (en) | 1986-02-28 |
| SU1250172A3 (ru) | 1986-08-07 |
| IE54816B1 (en) | 1990-02-14 |
| ZA831046B (en) | 1984-09-26 |
| FI830523L (fi) | 1983-09-04 |
| FI79308B (fi) | 1989-08-31 |
| ES520218A0 (es) | 1984-04-01 |
| NO830527L (no) | 1983-09-05 |
| FI830523A0 (fi) | 1983-02-16 |
| EP0087629A3 (en) | 1983-10-19 |
| ATE17480T1 (de) | 1986-02-15 |
| NZ203317A (en) | 1985-07-12 |
| DK161320C (da) | 1991-12-09 |
| ES8403884A1 (es) | 1984-04-01 |
| DE3361812D1 (en) | 1986-02-27 |
| CA1242725A (en) | 1988-10-04 |
| DK67683D0 (da) | 1983-02-16 |
| PT76247B (en) | 1986-02-04 |
| JPS58159489A (ja) | 1983-09-21 |
| EP0087629B1 (en) | 1986-01-15 |
| EP0087629A2 (en) | 1983-09-07 |
| IL67940A0 (en) | 1983-06-15 |
| AU553269B2 (en) | 1986-07-10 |
| JPH0314312B2 (es) | 1991-02-26 |
| AU1146083A (en) | 1983-09-08 |
| DK161320B (da) | 1991-06-24 |
| GR78135B (es) | 1984-09-26 |
| NO155198B (no) | 1986-11-17 |
| PT76247A (en) | 1983-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Record of annual fee payments |
Year of fee payment: 9 |