NO177863C - Fremgangsmåte for fremstilling av rekombinant humant IFN-type I, IFN1, IFN-pseudo-2, -3, og -4, samt ekspresjonsvektorer - Google Patents

Fremgangsmåte for fremstilling av rekombinant humant IFN-type I, IFN1, IFN-pseudo-2, -3, og -4, samt ekspresjonsvektorer

Info

Publication number
NO177863C
NO177863C NO853012A NO853012A NO177863C NO 177863 C NO177863 C NO 177863C NO 853012 A NO853012 A NO 853012A NO 853012 A NO853012 A NO 853012A NO 177863 C NO177863 C NO 177863C
Authority
NO
Norway
Prior art keywords
ifn
ifn1
pseudo
preparation
expression vectors
Prior art date
Application number
NO853012A
Other languages
English (en)
Norwegian (no)
Other versions
NO177863B (no
NO853012L (no
Inventor
Rudolf Hauptmann
Peter Meindl
Eva Dworkin-Rastl
Gunther Adolf
Peter Swetly
Christiann Pieler
Norbert Hauel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/de
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/de
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NO853012L publication Critical patent/NO853012L/no
Publication of NO177863B publication Critical patent/NO177863B/no
Publication of NO177863C publication Critical patent/NO177863C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO853012A 1984-08-01 1985-07-30 Fremgangsmåte for fremstilling av rekombinant humant IFN-type I, IFN1, IFN-pseudo-2, -3, og -4, samt ekspresjonsvektorer NO177863C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3428370A DE3428370A1 (de) 1984-08-01 1984-08-01 Interferon, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen
DE19853505060 DE3505060A1 (de) 1985-02-14 1985-02-14 Neue interferone vom typ i, genetische sequenzen, die hierfuer codieren, und diese produzierende organismen

Publications (3)

Publication Number Publication Date
NO853012L NO853012L (no) 1986-02-03
NO177863B NO177863B (no) 1995-08-28
NO177863C true NO177863C (no) 1995-12-06

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
NO853012A NO177863C (no) 1984-08-01 1985-07-30 Fremgangsmåte for fremstilling av rekombinant humant IFN-type I, IFN1, IFN-pseudo-2, -3, og -4, samt ekspresjonsvektorer

Country Status (21)

Country Link
EP (1) EP0170204B1 (es)
JP (2) JP2566909B2 (es)
KR (1) KR0136799B1 (es)
AT (1) ATE67786T1 (es)
AU (1) AU600653B2 (es)
BG (1) BG60445B2 (es)
CA (1) CA1340184C (es)
DD (1) DD246318A5 (es)
DE (1) DE3584198D1 (es)
DK (1) DK175194B1 (es)
ES (2) ES8609475A1 (es)
FI (1) FI90667C (es)
GR (1) GR851866B (es)
HK (1) HK187896A (es)
HU (1) HU205779B (es)
IE (1) IE58942B1 (es)
IL (1) IL75963A (es)
MX (1) MX9203645A (es)
NO (1) NO177863C (es)
NZ (1) NZ212937A (es)
PT (1) PT80901B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
EP0490233A1 (de) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonale Antikörper gegen BgIII-Hybridinterferone, deren Verwendung und Verfahren zu ihrer Herstellung
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
DE3635867A1 (de) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
CA2309766C (en) 1997-11-20 2008-09-30 Vical Incorporated Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
AU2004236174B2 (en) 2001-10-10 2011-06-02 Novo Nordisk A/S Glycopegylation methods and proteins/peptides produced by the methods
CA2818688A1 (en) * 2002-03-07 2003-09-12 Eidgenossische Technische Hochschule Zurich System and method for the production of recombinant glycosylated proteins in a prokaryotic host
DK1481057T3 (da) 2002-03-07 2006-05-15 Eidgenoess Tech Hochschule System og fremgangsmåde til fremstilling af rekombinante glycosylerede proteiner i en prokaryot vært
WO2004096852A1 (fr) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla Interferon$g(v) humain recombinant, son procede d'expression et ses utilisations
ES2353814T3 (es) 2005-05-11 2011-03-07 Eth Zuerich Proteinas n-glicosiladas recombinantes de celulas procariotas.
CN101983070B (zh) 2008-02-20 2016-03-30 格林考瓦因有限公司 由来源于原核细胞的重组n-糖基化蛋白制备生物共轭物
DK2501406T3 (en) 2009-11-19 2018-02-26 Glaxosmithkline Biologicals Sa BIOSYNTHESE SYSTEM PRODUCING IMMUNOGENIC POLYSACCHARIDES IN PROCARYOTIC CELLS
KR20130063510A (ko) 2010-05-06 2013-06-14 글리코박신 아게 캡슐형 그람-양성 세균 생체접합체 백신
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
DE3247922A1 (de) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten
DE3574145D1 (en) * 1984-08-27 1989-12-14 Genentech Inc Novel, distinct family of human leukocyte interferons, compositions containing them, methods for their production, and dna and transfected hosts therefor

Also Published As

Publication number Publication date
DE3584198D1 (de) 1991-10-31
ATE67786T1 (de) 1991-10-15
KR870001310A (ko) 1987-03-13
NO177863B (no) 1995-08-28
HK187896A (en) 1996-10-18
DK346385D0 (da) 1985-07-30
GR851866B (es) 1985-12-02
PT80901A (de) 1985-09-01
EP0170204A2 (de) 1986-02-05
IE58942B1 (en) 1993-12-01
NO853012L (no) 1986-02-03
FI90667B (fi) 1993-11-30
FI852956A0 (fi) 1985-07-31
JP2566909B2 (ja) 1996-12-25
ES545725A0 (es) 1986-08-01
JP2567195B2 (ja) 1996-12-25
HU205779B (en) 1992-06-29
PT80901B (pt) 1989-01-17
EP0170204A3 (en) 1988-02-17
MX9203645A (es) 1992-09-01
NZ212937A (en) 1991-08-27
JPH06181771A (ja) 1994-07-05
DK175194B1 (da) 2004-07-05
JPS61181381A (ja) 1986-08-14
ES8609475A1 (es) 1986-08-01
IL75963A (en) 1992-05-25
AU4554985A (en) 1986-02-06
AU600653B2 (en) 1990-08-23
ES8708013A1 (es) 1987-09-01
BG60445B2 (bg) 1995-03-31
IE851906L (en) 1986-02-01
DK346385A (da) 1986-02-02
FI852956L (fi) 1986-02-02
FI90667C (fi) 1994-03-10
EP0170204B1 (de) 1991-09-25
CA1340184C (en) 1998-12-15
ES552431A0 (es) 1987-09-01
DD246318A5 (de) 1987-06-03
HUT39477A (en) 1986-09-29
KR0136799B1 (ko) 1998-04-25
IL75963A0 (en) 1985-12-31

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