NO177006C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-R2-R4-substituert-3-R3-CO-1-[(C-tilknyttet-N-heteryl)-(Alk)nÅ-1H-indoler, samt mellomprodukt for bruk i denne - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-R2-R4-substituert-3-R3-CO-1-[(C-tilknyttet-N-heteryl)-(Alk)nÅ-1H-indoler, samt mellomprodukt for bruk i denne

Info

Publication number
NO177006C
NO177006C NO910731A NO910731A NO177006C NO 177006 C NO177006 C NO 177006C NO 910731 A NO910731 A NO 910731A NO 910731 A NO910731 A NO 910731A NO 177006 C NO177006 C NO 177006C
Authority
NO
Norway
Prior art keywords
heteryl
alk
substituted
preparation
therapeutically active
Prior art date
Application number
NO910731A
Other languages
English (en)
Other versions
NO910731D0 (no
NO910731L (no
NO177006B (no
Inventor
Ambra Thomas Edward D
Edward Richard Bacon
Malcolm Rice Bell
Philip Michael Carabateas
Michael Allen Eissenstat
Virendra Kumar
John Peter Mallamo
Susan Jean Ward
Original Assignee
Sterling Winthrop Inc
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc, Sterling Drug Inc filed Critical Sterling Winthrop Inc
Publication of NO910731D0 publication Critical patent/NO910731D0/no
Publication of NO910731L publication Critical patent/NO910731L/no
Publication of NO177006B publication Critical patent/NO177006B/no
Publication of NO177006C publication Critical patent/NO177006C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
NO910731A 1990-02-26 1991-02-25 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-R2-R4-substituert-3-R3-CO-1-[(C-tilknyttet-N-heteryl)-(Alk)nÅ-1H-indoler, samt mellomprodukt for bruk i denne NO177006C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/484,759 US5068234A (en) 1990-02-26 1990-02-26 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles

Publications (4)

Publication Number Publication Date
NO910731D0 NO910731D0 (no) 1991-02-25
NO910731L NO910731L (no) 1991-08-27
NO177006B NO177006B (no) 1995-03-27
NO177006C true NO177006C (no) 1995-07-05

Family

ID=23925489

Family Applications (1)

Application Number Title Priority Date Filing Date
NO910731A NO177006C (no) 1990-02-26 1991-02-25 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-R2-R4-substituert-3-R3-CO-1-[(C-tilknyttet-N-heteryl)-(Alk)nÅ-1H-indoler, samt mellomprodukt for bruk i denne

Country Status (17)

Country Link
US (4) US5068234A (no)
EP (1) EP0444451A3 (no)
JP (1) JPH0741475A (no)
KR (1) KR100191258B1 (no)
AU (1) AU638795B2 (no)
CA (1) CA2035711A1 (no)
FI (1) FI910851A (no)
HU (1) HU208132B (no)
IE (1) IE910492A1 (no)
IL (1) IL97313A (no)
MX (1) MX24568A (no)
MY (1) MY107158A (no)
NO (1) NO177006C (no)
NZ (1) NZ237041A (no)
PT (1) PT96871B (no)
RU (1) RU2052457C1 (no)
SG (1) SG55090A1 (no)

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US5486525A (en) * 1993-12-16 1996-01-23 Abbott Laboratories Platelet activating factor antagonists: imidazopyridine indoles
US5532237A (en) * 1995-02-15 1996-07-02 Merck Frosst Canada, Inc. Indole derivatives with affinity for the cannabinoid receptor
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GB2308362A (en) * 1995-12-19 1997-06-25 Lilly Industries Ltd Pharmaceutical indole derivatives
NZ335810A (en) * 1996-12-10 2001-03-30 Abbott Lab 3-(2-azetidinyl-methoxy)-pyridine derivatives useful as analgesics and azetidinyl intermediates
US6132762A (en) * 1997-05-05 2000-10-17 Cristobal; Walter Transcutaneous application of marijuana
ATE247097T1 (de) * 1998-05-04 2003-08-15 Univ Connecticut Analgetische und immunomodulierende cannabinoiden
US6166069A (en) * 1998-05-12 2000-12-26 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6479535B1 (en) 1998-05-15 2002-11-12 Wyeth 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
MXPA02005103A (es) 1999-10-18 2003-09-25 Alexipharma Inc Ligandos selectivos del receptor de canabinoide (cb2) perifericos.
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
EP1702617A1 (en) * 1999-10-18 2006-09-20 The University Of Connecticut Cannabimimetic indole derivatives
WO2001040183A1 (en) * 1999-12-03 2001-06-07 Alcon Universal Ltd. 1-aminoalkyl-1h-indoles for treating glaucoma
WO2002026728A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AUPR118000A0 (en) * 2000-11-02 2000-11-23 Amrad Operations Pty. Limited Therapeutic molecules and methods
JP2004532185A (ja) * 2001-01-26 2004-10-21 ユニバーシティ オブ コネチカット 新規なカンナビミメティックリガンド
US7173027B2 (en) 2001-01-29 2007-02-06 University Of Connecticut Receptor selective cannabimimetic aminoalkylindoles
EP1414775B1 (en) * 2001-07-13 2012-12-19 The University of Connecticut Bicyclic cannabinoid
JP2003040866A (ja) * 2001-07-31 2003-02-13 Nippon Kayaku Co Ltd Ｎ置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤
EP1448557A4 (en) * 2001-10-26 2005-02-02 Univ Connecticut HETEROINDANE: A NEW CLASS OF HIGH-ACTIVITY CANNABIMIMETIC LIGANDS
AU2003214226A1 (en) * 2002-03-18 2003-10-08 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
JP2006517194A (ja) 2002-06-06 2006-07-20 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム 骨成長を調節するための方法、組成物および製造物
JP2006511460A (ja) 2002-08-23 2006-04-06 ユニバーシティ オブ コネチカット 治療適応を持つケトカンナビノイド
US7276608B2 (en) 2003-07-11 2007-10-02 Bristol-Myers Squibb Company Tetrahydroquinoline derivatives as cannabinoid receptor modulators
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BRPI0608030A2 (pt) * 2005-03-12 2009-11-03 Unilever Nv usos de um composto de terpenóide
DE102009056426A1 (de) 2009-09-03 2011-03-10 Liebherr-Hausgeräte Ochsenhausen GmbH Unterbaugruppenelement für ein Kühl- und/oder Gefriergerät, Kühl- und/oder Gefriergerät sowie Verfahren zur Montage eines Kühl- und/oder Gefriergerätes
CN102838525A (zh) * 2012-09-04 2012-12-26 江苏昊华精细化工有限公司 1-戊基-3-(1萘甲酰基)吲哚的合成方法

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Also Published As

Publication number Publication date
AU638795B2 (en) 1993-07-08
US5607933A (en) 1997-03-04
SG55090A1 (en) 1998-12-21
JPH0741475A (ja) 1995-02-10
HU208132B (en) 1993-08-30
IE910492A1 (en) 1991-08-28
AU7122291A (en) 1991-08-29
EP0444451A2 (en) 1991-09-04
RU2052457C1 (ru) 1996-01-20
PT96871B (pt) 1998-07-31
MY107158A (en) 1995-09-30
US5324737A (en) 1994-06-28
IL97313A (en) 1995-07-31
CA2035711A1 (en) 1991-08-27
HUT56565A (en) 1991-09-30
US5068234A (en) 1991-11-26
KR910021399A (ko) 1991-12-20
MX24568A (es) 1993-09-01
NZ237041A (en) 1992-11-25
US5817651A (en) 1998-10-06
PT96871A (pt) 1991-10-31
FI910851A0 (fi) 1991-02-22
FI910851A (fi) 1991-08-27
NO910731D0 (no) 1991-02-25
NO910731L (no) 1991-08-27
NO177006B (no) 1995-03-27
HU910400D0 (en) 1991-08-28
EP0444451A3 (en) 1992-04-08
KR100191258B1 (ko) 1999-06-15
IL97313A0 (en) 1992-05-25

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