MX24568A - 3-arilcarbonil-1h-indoles y procedimiento para su preparacion. - Google Patents
3-arilcarbonil-1h-indoles y procedimiento para su preparacion.Info
- Publication number
- MX24568A MX24568A MX2456891A MX2456891A MX24568A MX 24568 A MX24568 A MX 24568A MX 2456891 A MX2456891 A MX 2456891A MX 2456891 A MX2456891 A MX 2456891A MX 24568 A MX24568 A MX 24568A
- Authority
- MX
- Mexico
- Prior art keywords
- arilcarbonil
- indoles
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/484,759 US5068234A (en) | 1990-02-26 | 1990-02-26 | 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX24568A true MX24568A (es) | 1993-09-01 |
Family
ID=23925489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2456891A MX24568A (es) | 1990-02-26 | 1991-02-15 | 3-arilcarbonil-1h-indoles y procedimiento para su preparacion. |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US5068234A (es) |
| EP (1) | EP0444451A3 (es) |
| JP (1) | JPH0741475A (es) |
| KR (1) | KR100191258B1 (es) |
| AU (1) | AU638795B2 (es) |
| CA (1) | CA2035711A1 (es) |
| FI (1) | FI910851A7 (es) |
| HU (1) | HU208132B (es) |
| IE (1) | IE910492A1 (es) |
| IL (1) | IL97313A (es) |
| MX (1) | MX24568A (es) |
| MY (1) | MY107158A (es) |
| NO (1) | NO177006C (es) |
| NZ (1) | NZ237041A (es) |
| PT (1) | PT96871B (es) |
| RU (1) | RU2052457C1 (es) |
| SG (1) | SG55090A1 (es) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5538973A (en) * | 1992-03-27 | 1996-07-23 | Kyoto Pharmaceutical Industries, Ltd. | Imidazole derivative, pharmaceutical use thereof, and intermediate therefor |
| AU684878B2 (en) * | 1993-11-24 | 1998-01-08 | Merck & Co., Inc. | Compounds and the use thereof to promote the release of growth hormone(s) |
| US5486525A (en) * | 1993-12-16 | 1996-01-23 | Abbott Laboratories | Platelet activating factor antagonists: imidazopyridine indoles |
| US5532237A (en) * | 1995-02-15 | 1996-07-02 | Merck Frosst Canada, Inc. | Indole derivatives with affinity for the cannabinoid receptor |
| FR2735774B1 (fr) * | 1995-06-21 | 1997-09-12 | Sanofi Sa | Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant |
| GB2308362A (en) * | 1995-12-19 | 1997-06-25 | Lilly Industries Ltd | Pharmaceutical indole derivatives |
| DE69717148T2 (de) * | 1996-12-10 | 2003-10-02 | Abbott Laboratories, Abbott Park | 3-pyridylenantiomere und ihre verwendung als analgetika |
| US6132762A (en) * | 1997-05-05 | 2000-10-17 | Cristobal; Walter | Transcutaneous application of marijuana |
| GB9716657D0 (en) * | 1997-08-07 | 1997-10-15 | Zeneca Ltd | Chemical compounds |
| BR9908301A (pt) * | 1998-02-27 | 2000-10-31 | Kissei Pharmaceutical | Derivados de indol e composições farmacêuticas que compreendem os mesmos |
| WO1999057106A1 (en) * | 1998-05-04 | 1999-11-11 | The University Of Connecticut | Novel analgesic and immunomodulatory cannabinoids |
| US6166069A (en) * | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6479535B1 (en) * | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
| US7897598B2 (en) * | 1998-06-09 | 2011-03-01 | Alexandros Makriyannis | Inhibitors of the anandamide transporter |
| US7589220B2 (en) * | 1998-06-09 | 2009-09-15 | University Of Connecticut | Inhibitors of the anandamide transporter |
| US7161016B1 (en) | 1998-11-24 | 2007-01-09 | University Of Connecticut | Cannabimimetic lipid amides as useful medications |
| US7276613B1 (en) | 1998-11-24 | 2007-10-02 | University Of Connecticut | Retro-anandamides, high affinity and stability cannabinoid receptor ligands |
| US6566560B2 (en) | 1999-03-22 | 2003-05-20 | Immugen Pharmaceuticals, Inc. | Resorcinolic compounds |
| MXPA02005103A (es) | 1999-10-18 | 2003-09-25 | Alexipharma Inc | Ligandos selectivos del receptor de canabinoide (cb2) perifericos. |
| US6943266B1 (en) | 1999-10-18 | 2005-09-13 | University Of Connecticut | Bicyclic cannabinoid agonists for the cannabinoid receptor |
| US7393842B2 (en) * | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
| US7119108B1 (en) * | 1999-10-18 | 2006-10-10 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
| EP1702617A1 (en) * | 1999-10-18 | 2006-09-20 | The University Of Connecticut | Cannabimimetic indole derivatives |
| US8084467B2 (en) * | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
| US6900236B1 (en) * | 1999-10-18 | 2005-05-31 | University Of Connecticut | Cannabimimetic indole derivatives |
| US7741365B2 (en) * | 1999-10-18 | 2010-06-22 | University Of Connecticut | Peripheral cannabinoid receptor (CB2) selective ligands |
| AU2042301A (en) * | 1999-12-03 | 2001-06-12 | Alcon Universal Limited | 1-aminoalkyl-1H-indoles for treating glaucoma |
| US20020137802A1 (en) * | 2000-09-28 | 2002-09-26 | Travis Craig R. | Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation |
| US6541510B2 (en) * | 2000-09-28 | 2003-04-01 | Immugen Pharmaceuticals, Inc. | Antiviral methods and compounds |
| AUPR118000A0 (en) * | 2000-11-02 | 2000-11-23 | Amrad Operations Pty. Limited | Therapeutic molecules and methods |
| WO2002058636A2 (en) * | 2001-01-26 | 2002-08-01 | University Of Connecticut | Novel cannabimimetic ligands |
| JP2005503998A (ja) * | 2001-01-29 | 2005-02-10 | ユニバーシティ オブ コネチカット | 受容体選択性のカンナビミメティックアミノアルキルインドール |
| TW200600497A (en) * | 2001-02-02 | 2006-01-01 | Sankyo Co | Preparation of indoline derivative |
| WO2003005960A2 (en) * | 2001-07-13 | 2003-01-23 | University Of Connecticut | Novel bicyclic and tricyclic cannabinoids |
| JP2003040866A (ja) * | 2001-07-31 | 2003-02-13 | Nippon Kayaku Co Ltd | Ｎ置換インドール誘導体、その製造法及びそれを有効成分とする害虫防除剤 |
| EP1423378B1 (en) * | 2001-08-30 | 2005-11-09 | F. Hoffmann-La Roche Ag | Aminopyrrole compounds as antiinflammatory agents |
| CN1589269A (zh) * | 2001-10-26 | 2005-03-02 | 康涅狄格大学 | 杂1,2－二氢化茚:一类新型有效的大麻配体 |
| WO2003080043A1 (en) * | 2002-03-18 | 2003-10-02 | Immugen Pharmaceuticals, Inc. | Topical formulations of resorcinols and cannibinoids and methods of use |
| DE60320784D1 (de) | 2002-06-06 | 2008-06-19 | Yissum Res Dev Co | Stände zur modulierung des knochenwachstums |
| AU2003265663A1 (en) | 2002-08-23 | 2004-03-11 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
| EP1644335A4 (en) | 2003-07-11 | 2008-06-04 | Bristol Myers Squibb Co | TETRAHYDROQUINOLINE DERIVATIVES COMPRISING MODULATORS OF CANNABINOID RECEPTORS |
| US7326706B2 (en) | 2003-08-15 | 2008-02-05 | Bristol-Myers Squibb Company | Pyrazine modulators of cannabinoid receptors |
| IL160420A0 (en) | 2004-02-16 | 2004-07-25 | Yissum Res Dev Co | Treating or preventing diabetes with cannabidiol |
| WO2006097193A1 (en) * | 2005-03-12 | 2006-09-21 | Unilever Plc | Hair and/or scalp care compositions incorporating amino-oxo-indole-ylidene compounds |
| RU2389487C2 (ru) * | 2005-03-12 | 2010-05-20 | Унилевер Нв | Композиции для ухода за волосами и/или кожей головы, включающие флавоноидные соединения |
| EP2236126A1 (en) * | 2005-03-12 | 2010-10-06 | Unilever PLC | Hair and/or Scalp Care Compositions Incorporating Isophaseollin |
| DE102009056426A1 (de) | 2009-09-03 | 2011-03-10 | Liebherr-Hausgeräte Ochsenhausen GmbH | Unterbaugruppenelement für ein Kühl- und/oder Gefriergerät, Kühl- und/oder Gefriergerät sowie Verfahren zur Montage eines Kühl- und/oder Gefriergerätes |
| CN102838525A (zh) * | 2012-09-04 | 2012-12-26 | 江苏昊华精细化工有限公司 | 1-戊基-3-(1萘甲酰基)吲哚的合成方法 |
| US12343337B2 (en) | 2016-09-29 | 2025-07-01 | The Regents Of The University Of California | Compounds for increasing neural plasticity |
| BR112021016620A2 (pt) | 2019-02-27 | 2021-11-03 | Univ California | Azepino-indóis e outros heterociclos para o tratamento de distúrbios cerebrais |
| CN113840600B (zh) * | 2019-02-27 | 2026-02-13 | 加利福尼亚大学董事会 | 用于治疗脑疾病的n-取代吲哚和其他杂环化合物 |
| KR20240150417A (ko) | 2021-12-15 | 2024-10-15 | 델릭스 테라퓨틱스, 인크. | 페녹시 및 벤질옥시로 치환된 사이코플라스토겐 및 그의 용도 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3361759A (en) * | 1963-10-07 | 1968-01-02 | Upjohn Co | 3-(2-pyrrolidinyl)-indoles and method of preparation |
| BR6570394D0 (pt) * | 1964-07-02 | 1973-08-14 | Merck & Co Inc | Processo para a preparacao de compostos da serie indolica |
| US3471499A (en) * | 1965-12-03 | 1969-10-07 | American Home Prod | 1,4-bis-(2-indol-3-yl-ethyl)piperazines |
| US3481953A (en) * | 1967-12-18 | 1969-12-02 | American Home Prod | 1-arylsulfonyl-3-(2-substituted ethyl) indoles |
| GB1374414A (en) * | 1972-06-12 | 1974-11-20 | Sterling Drug Inc | 1-acyl-3-amino-alkyl-indoles and their preparation |
| GB1436771A (en) * | 1973-02-16 | 1976-05-26 | Labaz | Indole derivatives and process for preparing the same |
| FR2354766A1 (fr) * | 1976-06-17 | 1978-01-13 | Labaz | Derives n-aminoalkyles d'indole et procedes pour les preparer |
| US4581354A (en) * | 1984-08-06 | 1986-04-08 | Sterling Drug Inc. | 3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use |
| USRE32761E (en) * | 1984-08-06 | 1988-10-04 | Sterling Drug Inc. | 3-arylcarbonyl and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use |
| PH23498A (en) * | 1984-08-06 | 1989-08-16 | Sterling Drug Inc | 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof |
| US4634776A (en) * | 1984-08-06 | 1987-01-06 | Sterling Drug, Inc. | 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles |
| US4774243A (en) * | 1985-12-24 | 1988-09-27 | Merck & Co., Inc. | Dopamine agonists for treating elevated intraocular pressure |
| DE68909253T2 (de) * | 1988-01-15 | 1994-02-24 | Abbott Lab | 1-Aminomethyl-1,2,3,4-tetrahydronaphthaline und -indane. |
| DE3907974A1 (de) * | 1989-03-11 | 1990-09-13 | Merck Patent Gmbh | Indolderivate |
| US4973587A (en) * | 1990-03-08 | 1990-11-27 | Sterling Drug Inc. | 3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method |
| CA2036307C (en) * | 1990-03-08 | 2002-07-09 | Susan Jean Ward | 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method |
| EP0471296B1 (en) * | 1990-08-13 | 1995-11-08 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-(Pyridinylalkyl)-1H-indoles, indolines and related analogs |
-
1990
- 1990-02-26 US US07/484,759 patent/US5068234A/en not_active Expired - Fee Related
-
1991
- 1991-02-05 CA CA002035711A patent/CA2035711A1/en not_active Abandoned
- 1991-02-06 HU HU91400A patent/HU208132B/hu not_active IP Right Cessation
- 1991-02-07 EP EP19910101689 patent/EP0444451A3/en not_active Withdrawn
- 1991-02-07 SG SG1996005643A patent/SG55090A1/en unknown
- 1991-02-07 NZ NZ237041A patent/NZ237041A/xx unknown
- 1991-02-13 IE IE049291A patent/IE910492A1/en unknown
- 1991-02-15 MX MX2456891A patent/MX24568A/es unknown
- 1991-02-20 IL IL9731391A patent/IL97313A/en not_active IP Right Cessation
- 1991-02-20 AU AU71222/91A patent/AU638795B2/en not_active Ceased
- 1991-02-20 MY MYPI91000268A patent/MY107158A/en unknown
- 1991-02-22 FI FI910851A patent/FI910851A7/fi unknown
- 1991-02-23 KR KR1019910002970A patent/KR100191258B1/ko not_active Expired - Fee Related
- 1991-02-25 NO NO910731A patent/NO177006C/no unknown
- 1991-02-25 PT PT96871A patent/PT96871B/pt not_active IP Right Cessation
- 1991-02-26 JP JP3030804A patent/JPH0741475A/ja active Pending
- 1991-09-26 US US07/807,032 patent/US5324737A/en not_active Expired - Fee Related
-
1992
- 1992-05-27 RU SU925011741A patent/RU2052457C1/ru active
-
1994
- 1994-03-16 US US08/213,777 patent/US5607933A/en not_active Expired - Fee Related
-
1997
- 1997-01-14 US US08/783,161 patent/US5817651A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO177006C (no) | 1995-07-05 |
| HUT56565A (en) | 1991-09-30 |
| HU910400D0 (en) | 1991-08-28 |
| KR100191258B1 (ko) | 1999-06-15 |
| RU2052457C1 (ru) | 1996-01-20 |
| NO910731D0 (no) | 1991-02-25 |
| SG55090A1 (en) | 1998-12-21 |
| IL97313A (en) | 1995-07-31 |
| US5817651A (en) | 1998-10-06 |
| FI910851A0 (fi) | 1991-02-22 |
| NO177006B (no) | 1995-03-27 |
| HU208132B (en) | 1993-08-30 |
| US5324737A (en) | 1994-06-28 |
| PT96871A (pt) | 1991-10-31 |
| MY107158A (en) | 1995-09-30 |
| NO910731L (no) | 1991-08-27 |
| KR910021399A (ko) | 1991-12-20 |
| NZ237041A (en) | 1992-11-25 |
| EP0444451A3 (en) | 1992-04-08 |
| JPH0741475A (ja) | 1995-02-10 |
| AU7122291A (en) | 1991-08-29 |
| PT96871B (pt) | 1998-07-31 |
| FI910851A7 (fi) | 1991-08-27 |
| US5068234A (en) | 1991-11-26 |
| IE910492A1 (en) | 1991-08-28 |
| EP0444451A2 (en) | 1991-09-04 |
| AU638795B2 (en) | 1993-07-08 |
| US5607933A (en) | 1997-03-04 |
| IL97313A0 (en) | 1992-05-25 |
| CA2035711A1 (en) | 1991-08-27 |
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