NO174465C - Analogifremgangsmåte ved fremstilling av terapeutisk aktive 1-acyl-2,3-dihydro-4-(1H)-kinolinon-4-oksimderivater - Google Patents

Analogifremgangsmåte ved fremstilling av terapeutisk aktive 1-acyl-2,3-dihydro-4-(1H)-kinolinon-4-oksimderivater

Info

Publication number
NO174465C
NO174465C NO875495A NO875495A NO174465C NO 174465 C NO174465 C NO 174465C NO 875495 A NO875495 A NO 875495A NO 875495 A NO875495 A NO 875495A NO 174465 C NO174465 C NO 174465C
Authority
NO
Norway
Prior art keywords
quinolinone
dihydro
acyl
therapeutically active
oxime derivatives
Prior art date
Application number
NO875495A
Other languages
English (en)
Norwegian (no)
Other versions
NO875495D0 (no
NO174465B (no
NO875495L (no
Inventor
Ei Mochida
Akio Uemura
Kazuo Kato
Hiroki Tokunaga
Akinori Haga
Original Assignee
Mochida Pharm Co Ltd
Hodogaya Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP62092788A external-priority patent/JPS63239270A/ja
Application filed by Mochida Pharm Co Ltd, Hodogaya Chemical Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of NO875495D0 publication Critical patent/NO875495D0/no
Publication of NO875495L publication Critical patent/NO875495L/no
Publication of NO174465B publication Critical patent/NO174465B/no
Publication of NO174465C publication Critical patent/NO174465C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/42Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO875495A 1986-05-02 1987-12-30 Analogifremgangsmåte ved fremstilling av terapeutisk aktive 1-acyl-2,3-dihydro-4-(1H)-kinolinon-4-oksimderivater NO174465C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10284786 1986-05-02
JP62092788A JPS63239270A (ja) 1986-05-02 1987-04-15 1−アシル−2,3−ジヒドロ−4(1h)−キノリノン−4−オキシム誘導体、その製法、およびそれらを主成分とする利尿、降圧、抗浮腫および腹水除去剤
PCT/JP1987/000276 WO1987006580A1 (en) 1986-05-02 1987-05-01 1-acyl-2,3-dihydro-4(1h)-quinolinone-4-oxime derivatives

Publications (4)

Publication Number Publication Date
NO875495D0 NO875495D0 (no) 1987-12-30
NO875495L NO875495L (no) 1988-03-01
NO174465B NO174465B (no) 1994-01-31
NO174465C true NO174465C (no) 1994-05-11

Family

ID=26434165

Family Applications (1)

Application Number Title Priority Date Filing Date
NO875495A NO174465C (no) 1986-05-02 1987-12-30 Analogifremgangsmåte ved fremstilling av terapeutisk aktive 1-acyl-2,3-dihydro-4-(1H)-kinolinon-4-oksimderivater

Country Status (18)

Country Link
US (2) US4839368A (de)
EP (1) EP0243982B1 (de)
AU (2) AU596657B2 (de)
CA (1) CA1314888C (de)
DE (1) DE3769358D1 (de)
DK (1) DK171379B1 (de)
ES (1) ES2036542T3 (de)
FI (1) FI90071C (de)
GR (1) GR3001800T3 (de)
HU (1) HU199803B (de)
IE (1) IE60105B1 (de)
IL (1) IL82399A0 (de)
NO (1) NO174465C (de)
NZ (1) NZ220168A (de)
RU (1) RU1779246C (de)
SU (1) SU1722227A3 (de)
WO (1) WO1987006580A1 (de)
ZW (1) ZW7887A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4839368A (en) * 1986-05-02 1989-06-13 Mochida Pharmaceutical Co., Ltd. 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives
JP2602037B2 (ja) * 1987-10-31 1997-04-23 持田製薬株式会社 1−アシル−2,3−ジヒドロ−4(1h)−キノリノン−4−オキシム誘導体、その製法およびそれらを主成分とする利尿、降圧、抗浮腫および腹水除去用医薬組成物
AU661159B2 (en) * 1992-07-15 1995-07-13 Sumitomo Chemical Company, Limited N-acyldihydroquinoline derivatives, a method for producing the same and their use as herbicides
ES2284741T3 (es) 1994-06-15 2007-11-16 Otsuka Pharmaceutical Company, Limited Derivados de benzoheterociclicos utilizados como moduladores de vasoprsinao de oxitocina.
HN2000000203A (es) 1999-11-30 2001-06-13 Pfizer Prod Inc Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas 4-carboxiamino-2- sustituidas.
GB2532990A (en) 2014-12-05 2016-06-08 Schlumberger Holdings Corrosion inhibition
GB2543498A (en) 2015-10-19 2017-04-26 Schlumberger Holdings Corrosion inhibition

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013662A (en) * 1974-12-19 1977-03-22 Pfizer Inc. Alkyl and benzyl 6,7-dialkoxy-2-methyl-4-oxo-1,2,3,4-tetrahydroquinoline-1-carboxylates
US3976650A (en) * 1975-11-04 1976-08-24 Pfizer Inc. Process for preparing optically active 6,7-dimethoxy-2-methyl-4-oxo-1,2,3,4-tetrahydro-1-quinoline carboxylic acid ester analgesics
US4260764A (en) * 1976-12-22 1981-04-07 Pfizer Inc. 9-Hydroxyoctahydrobenzo [C] quinolines and intermediates therefor
GB2092130B (en) * 1980-07-28 1984-05-10 Hodogaya Chemical Co Ltd 4-oximino-1,2,3,4-tetrahydroquinoline derivatives
US4421919A (en) * 1980-07-28 1983-12-20 Hodogaya Chemical Co., Ltd. 4-Oximino-1,2,3,4-tetrahydroquinoline derivatives
GB2081091B (en) * 1980-07-28 1984-03-07 Mochida Pharm Co Ltd Hypotensive diuretic pharmaceutical compositions containing tetrahydroquinoline derivatives
US4521607A (en) * 1981-02-27 1985-06-04 Takeda Chemical Industries, Ltd. Chromanyl glycines
CA1189078A (en) * 1982-07-30 1985-06-18 Hodogaya Chemical Co., Ltd. Process for producing 4-oximino-1,2,3,4- tetrahydroquinoline derivatives and said derivatives produced thereby
DE3416695A1 (de) * 1984-05-05 1985-11-07 Bayer Ag, 5090 Leverkusen Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
PH21213A (en) * 1984-10-26 1987-08-21 Fujisawa Pharmaceutical Co Benzene- and pyrazole- fused heterocyclic compound and pharmaceutical composition comprising the same
DE3660255D1 (en) * 1985-04-12 1988-07-07 Ciba Geigy Ag Oxime sulphonates containing reactive groups
US4839368A (en) * 1986-05-02 1989-06-13 Mochida Pharmaceutical Co., Ltd. 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives

Also Published As

Publication number Publication date
NO875495D0 (no) 1987-12-30
NO174465B (no) 1994-01-31
IE60105B1 (en) 1994-06-01
WO1987006580A1 (en) 1987-11-05
HU199803B (en) 1990-03-28
NO875495L (no) 1988-03-01
AU630716B2 (en) 1992-11-05
FI875771A (fi) 1987-12-30
AU7244187A (en) 1987-11-05
AU596657B2 (en) 1990-05-10
US4839368A (en) 1989-06-13
DE3769358D1 (de) 1991-05-23
GR3001800T3 (en) 1992-11-23
DK171379B1 (da) 1996-10-07
CA1314888C (en) 1993-03-23
AU5861890A (en) 1990-11-15
EP0243982A1 (de) 1987-11-04
ES2036542T3 (es) 1993-06-01
IE871154L (en) 1987-11-02
DK694487A (da) 1988-03-02
FI90071B (fi) 1993-09-15
DK694487D0 (da) 1987-12-30
IL82399A0 (en) 1987-11-30
RU1779246C (ru) 1992-11-30
SU1722227A3 (ru) 1992-03-23
US5077410A (en) 1991-12-31
HUT47912A (en) 1989-04-28
FI90071C (fi) 1993-12-27
FI875771A0 (fi) 1987-12-30
NZ220168A (en) 1990-02-26
ZW7887A1 (en) 1987-09-09
EP0243982B1 (de) 1991-04-17

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