NO174207C - Analogifremgangsmåte for fremstilling av terapeutisk aktivt konjugat av membrananker-virksomt stoff - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktivt konjugat av membrananker-virksomt stoff

Info

Publication number
NO174207C
NO174207C NO862511A NO862511A NO174207C NO 174207 C NO174207 C NO 174207C NO 862511 A NO862511 A NO 862511A NO 862511 A NO862511 A NO 862511A NO 174207 C NO174207 C NO 174207C
Authority
NO
Norway
Prior art keywords
active ingredient
preparation
therapeutically active
analogous process
active conjugate
Prior art date
Application number
NO862511A
Other languages
English (en)
Norwegian (no)
Other versions
NO174207B (no
NO862511L (no
NO862511D0 (no
Inventor
Gunther Jung
Karl-Heinz Wiesmuller
Jorg Metzger
Hans-Jorg Buhring
Gerhard Becker
Wolfgang Bessler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO862511D0 publication Critical patent/NO862511D0/no
Publication of NO862511L publication Critical patent/NO862511L/no
Priority to NO920356A priority Critical patent/NO920356D0/no
Publication of NO174207B publication Critical patent/NO174207B/no
Publication of NO174207C publication Critical patent/NO174207C/no

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02Peptides being immobilised on, or in, an organic carrier
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018Lipids, e.g. in lipopeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Materials For Medical Uses (AREA)
NO862511A 1985-06-24 1986-06-23 Analogifremgangsmåte for fremstilling av terapeutisk aktivt konjugat av membrananker-virksomt stoff NO174207C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO920356A NO920356D0 (no) 1985-06-24 1992-01-27 Analogifremgangsmaate for fremstilling av et konjugat av et membrananker-virksomt stoff

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3522512 1985-06-24
DE19853546150 DE3546150A1 (de) 1985-06-24 1985-12-27 Membrananker-wirkstoffkonjugat, seine herstellung sowie seine verwendung

Publications (4)

Publication Number Publication Date
NO862511D0 NO862511D0 (no) 1986-06-23
NO862511L NO862511L (no) 1986-12-29
NO174207B NO174207B (no) 1993-12-20
NO174207C true NO174207C (no) 1994-03-30

Family

ID=25833375

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862511A NO174207C (no) 1985-06-24 1986-06-23 Analogifremgangsmåte for fremstilling av terapeutisk aktivt konjugat av membrananker-virksomt stoff

Country Status (12)

Country Link
EP (1) EP0210412B1 (fr)
JP (1) JP2594259B2 (fr)
KR (1) KR930008091B1 (fr)
AT (1) ATE131491T1 (fr)
AU (1) AU611385B2 (fr)
CA (1) CA1340656C (fr)
DE (2) DE3546150A1 (fr)
DK (1) DK172399B1 (fr)
ES (1) ES8801677A1 (fr)
FI (1) FI94419C (fr)
NO (1) NO174207C (fr)
PT (1) PT82826B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3813821A1 (de) * 1988-04-22 1989-11-02 Hoechst Ag Synthetische vakzine gegen die maul- und klauenseuche und verfahren zu deren herstellung
US6074650A (en) * 1985-06-24 2000-06-13 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
DE3937412A1 (de) * 1989-11-10 1991-05-16 Hoechst Ag Synthetische vakzine zur spezifischen induktion zytotoxischer t-lymphozyten
US6024964A (en) * 1985-06-24 2000-02-15 Hoechst Aktiengesellschaft Membrane anchor/active compound conjugate, its preparation and its uses
AU619443B2 (en) * 1986-04-21 1992-01-30 Bioenterprises Pty. Ltd. Immunopotentiation
CA1331355C (fr) * 1986-04-21 1994-08-09 Bioenterprises Pty. Ltd Immunopotentialisation
JPS63107742A (ja) * 1986-05-20 1988-05-12 Wako Pure Chem Ind Ltd 新規な機能性リポソ−ム及びその製造法
DE3700173A1 (de) * 1987-01-05 1988-07-14 Hoechst Ag Verfahren zur herstellung von lipophilen aminosaeurederivaten sowie lipophile aminosaeurederivate
US5976839A (en) * 1987-03-13 1999-11-02 Bioenterprises Pty Limited Immunopotentiation through covalent linkage between immunogen and immunopotentiating molecules
GB2217319A (en) * 1988-04-19 1989-10-25 Synpharm Ltd Racemic and optically active fatty amino acids, their homo- abd hetero-oligomers and conjugates, the process of their production, their pharmaceutical composi
US5120829A (en) * 1989-03-20 1992-06-09 La Jolla Cancer Research Foundation Hydrophobic attachment site for adhesion peptides
DE59103985D1 (en) * 1990-05-30 1995-02-02 Deutsches Krebsforsch Polyethersubstituierte tumormittel.
DE4119856A1 (de) * 1991-06-17 1992-12-24 Hoechst Ag N-acyl-s-(2-hydroxyalkyl)-cysteine, deren herstellung sowie deren verwendung als zwischenprodukte zur herstellung von synthetischen immunadjuvantien und synthetischen impfstoffen
EP0604945A1 (fr) * 1992-12-28 1994-07-06 Takeda Chemical Industries, Ltd. TAN-1511, dérivés, préparation et utilisation
AU666789B2 (en) * 1992-12-28 1996-02-22 Takeda Chemical Industries Ltd. 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
DE4325317C2 (de) * 1993-07-29 1998-05-20 Univ Dresden Tech Verfahren zur radioaktiven Markierung von Immunglobulinen
DE4329309A1 (de) * 1993-08-31 1995-03-09 Rapp Polymere Gmbh Lipopeptid-Verbindungen
EP0641776A3 (fr) * 1993-09-08 1997-05-02 Takeda Chemical Industries Ltd Dérivés de thioglycérol.
FR2727117A1 (fr) * 1994-11-18 1996-05-24 Geffard Michel Utilisation de conjugues de la polylysine pour la preparation de medicaments utiles dans le traitement des maladies neurodegeneratives et des affections degeneratives a caractere autoimmun
US6117940A (en) * 1997-10-17 2000-09-12 Mjalli; Adnan M. M. Amino-ketone solid support templates
NZ506839A (en) * 1998-03-09 2003-05-30 Zealand Pharma As Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
IL125908A (en) * 1998-08-24 2005-05-17 Nst Neurosurvival Technologies Peptides and pharmaceutical compositions comprising same
IL131266A0 (en) 1999-08-05 2001-01-28 N S T Neurosurvival Technologi Peptides and pharmaceutical compositions comprising same
GB9915074D0 (en) * 1999-06-28 1999-08-25 Cortecs Plc Ligand-binding composition
DE102009034779A1 (de) 2009-07-25 2011-02-03 Emc Microcollections Gmbh Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen
EA031379B1 (ru) * 2010-03-23 2018-12-28 Новартис Аг Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний
DE102011018499A1 (de) 2011-04-23 2012-10-25 Emc Microcollections Gmbh Topische Nanopartikel-Vakzine zur Immunstimulation der dendritischen Zellen in der Haut
WO2014055754A1 (fr) * 2012-10-05 2014-04-10 The University Of Kansas Peptides coudés de dislocation endosomale à conformation contrainte
US10766928B2 (en) 2012-10-05 2020-09-08 The University Of Kansas Targeted conformationally-constrained kinked endosomal disrupting peptides
CN106232577B (zh) * 2014-04-25 2019-02-22 味之素株式会社 免疫刺激剂
DE102016005550B4 (de) 2016-05-09 2024-09-26 Hans-Georg Rammensee Adjuvans zur lnduzierung einer zellulären lmmunantwort
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
JP7761567B2 (ja) 2020-02-18 2025-10-28 ノヴォ ノルディスク アー/エス 医薬製剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000330B1 (fr) * 1977-06-20 1981-08-05 Ciba-Geigy Ag Lipopeptides, procédé pour leur préparation et compositions pharmaceutiques les contenant
US4125569A (en) 1977-08-25 1978-11-14 Mobil Oil Corporation Process for increasing hydrogenation rate of polymerized n-alphaolefins
EP0014815A3 (fr) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Dérivés peptidiques, procédé pour leur préparation et intermédiaires, et compositions pharmaceutiques contenant un de ces composés
EP0114787B1 (fr) * 1983-01-25 1991-09-25 Ciba-Geigy Ag Dérivés peptidiques

Also Published As

Publication number Publication date
CA1340656C (fr) 1999-07-20
FI94419C (fi) 1995-09-11
PT82826A (de) 1986-07-01
DK172399B1 (da) 1998-05-18
JPS6263600A (ja) 1987-03-20
AU5894386A (en) 1987-01-08
FI862631A7 (fi) 1986-12-25
ES8801677A1 (es) 1988-02-16
PT82826B (pt) 1989-01-17
DK294086A (da) 1986-12-25
KR930008091B1 (en) 1993-08-25
NO174207B (no) 1993-12-20
NO862511L (no) 1986-12-29
EP0210412A3 (en) 1990-02-07
KR870000359A (ko) 1987-02-18
ES556417A0 (es) 1988-02-16
DK294086D0 (da) 1986-06-23
EP0210412A2 (fr) 1987-02-04
NO862511D0 (no) 1986-06-23
JP2594259B2 (ja) 1997-03-26
DE3650448D1 (de) 1996-01-25
FI94419B (fi) 1995-05-31
EP0210412B1 (fr) 1995-12-13
FI862631A0 (fi) 1986-06-19
DE3546150A1 (de) 1987-01-22
ATE131491T1 (de) 1995-12-15
AU611385B2 (en) 1991-06-13

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Legal Events

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MK1K Patent expired