DE69624121D1 - Membranen possierende second messengers - Google Patents
Membranen possierende second messengersInfo
- Publication number
- DE69624121D1 DE69624121D1 DE69624121T DE69624121T DE69624121D1 DE 69624121 D1 DE69624121 D1 DE 69624121D1 DE 69624121 T DE69624121 T DE 69624121T DE 69624121 T DE69624121 T DE 69624121T DE 69624121 D1 DE69624121 D1 DE 69624121D1
- Authority
- DE
- Germany
- Prior art keywords
- messengers
- membranes
- possending
- image
- acyloxyalkyl esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012528 membrane Substances 0.000 title 1
- 125000005041 acyloxyalkyl group Chemical group 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000170 cell membrane Anatomy 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4075—Esters with hydroxyalkyl compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/475,758 US5834436A (en) | 1993-04-09 | 1995-06-07 | Membrane-permeant second messengers |
| PCT/US1996/009923 WO1996040695A1 (en) | 1995-06-07 | 1996-06-07 | Membrane-permeant second messengers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69624121D1 true DE69624121D1 (de) | 2002-11-07 |
| DE69624121T2 DE69624121T2 (de) | 2003-06-18 |
Family
ID=23889001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69624121T Expired - Fee Related DE69624121T2 (de) | 1995-06-07 | 1996-06-07 | Membranen possierende second messengers |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5834436A (de) |
| EP (1) | EP0842181B1 (de) |
| JP (1) | JPH11508240A (de) |
| AT (1) | ATE225355T1 (de) |
| AU (1) | AU709883B2 (de) |
| CA (1) | CA2220994A1 (de) |
| DE (1) | DE69624121T2 (de) |
| WO (1) | WO1996040695A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866548A (en) * | 1993-04-09 | 1999-02-02 | The Regents Of The University Of California | Caged membrane-permeant inositol phosphates |
| US5955453A (en) * | 1998-04-24 | 1999-09-21 | The Regents Of The University Of California | Membrane-permeant phosphoinositides |
| US6221856B1 (en) | 1999-02-03 | 2001-04-24 | Inologic, Inc. | Inositol derivatives for inhibiting superoxide anion production |
| US6812342B2 (en) | 2001-06-20 | 2004-11-02 | Board Of Regents, The University Of Texas System | Esters of cyclic ADP ribose derivatives |
| US20050181464A1 (en) * | 2002-04-04 | 2005-08-18 | Affinium Pharmaceuticals, Inc. | Novel purified polypeptides from bacteria |
| KR100578732B1 (ko) * | 2004-03-05 | 2006-05-12 | 학교법인 포항공과대학교 | 분자 수송체로서의 이노시톨 유도체 및 이의 제조방법 |
| KR100849033B1 (ko) * | 2006-09-07 | 2008-07-29 | 포항공과대학교 산학협력단 | 알디톨 또는 이노시톨 유도체를 골격으로 한 분자 수송체 |
| EP2927209A1 (de) | 2014-03-31 | 2015-10-07 | Afinitica Technologies, S. L. | Verfahren zur Herstellung von 1,1-disubstituierten äthylenischen Monomeren |
| EP4286369A1 (de) | 2022-06-03 | 2023-12-06 | Bostik SA | Biobasierte cyanoacrylatverbindung |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4515722A (en) * | 1982-03-30 | 1985-05-07 | Merck & Co., Inc. | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents |
| US4816570A (en) * | 1982-11-30 | 1989-03-28 | The Board Of Regents Of The University Of Texas System | Biologically reversible phosphate and phosphonate protective groups |
| US4968788A (en) * | 1986-04-04 | 1990-11-06 | Board Of Regents, The University Of Texas System | Biologically reversible phosphate and phosphonate protective gruops |
| US5428163A (en) * | 1986-12-31 | 1995-06-27 | Mills; Randell L. | Prodrugs for selective drug delivery |
| US4988682A (en) * | 1989-02-03 | 1991-01-29 | University Of Pittsburgh | Myo-inositol analogs and method for their use |
| US5053399A (en) * | 1989-02-03 | 1991-10-01 | University Of Pittsburgh | Myo-inositol analogs and methods for their use |
| US5210263A (en) * | 1990-05-15 | 1993-05-11 | University Of Pittsburgh | Inositol phosphate analogs and methods for their use |
| US5177064A (en) * | 1990-07-13 | 1993-01-05 | University Of Florida | Targeted drug delivery via phosphonate derivatives |
| US5227508A (en) * | 1992-01-24 | 1993-07-13 | Mayo Foundation For Medical Education And Research | 3-deoxy-3-substituted analogs of phosphatidylinositol |
| US5693521A (en) * | 1993-04-09 | 1997-12-02 | The Regents Of The University Of California | Membrane-permeant second messengers |
-
1995
- 1995-06-07 US US08/475,758 patent/US5834436A/en not_active Expired - Lifetime
-
1996
- 1996-06-07 JP JP9502088A patent/JPH11508240A/ja not_active Ceased
- 1996-06-07 AU AU61099/96A patent/AU709883B2/en not_active Ceased
- 1996-06-07 AT AT96918434T patent/ATE225355T1/de not_active IP Right Cessation
- 1996-06-07 WO PCT/US1996/009923 patent/WO1996040695A1/en active IP Right Grant
- 1996-06-07 CA CA002220994A patent/CA2220994A1/en not_active Abandoned
- 1996-06-07 DE DE69624121T patent/DE69624121T2/de not_active Expired - Fee Related
- 1996-06-07 EP EP96918434A patent/EP0842181B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU6109996A (en) | 1996-12-30 |
| EP0842181A1 (de) | 1998-05-20 |
| ATE225355T1 (de) | 2002-10-15 |
| US5834436A (en) | 1998-11-10 |
| EP0842181B1 (de) | 2002-10-02 |
| JPH11508240A (ja) | 1999-07-21 |
| DE69624121T2 (de) | 2003-06-18 |
| AU709883B2 (en) | 1999-09-09 |
| CA2220994A1 (en) | 1996-12-19 |
| EP0842181A4 (de) | 1998-11-25 |
| WO1996040695A1 (en) | 1996-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |