ES8303444A1 - "procedimiento de preparacion de disacaridos". - Google Patents
"procedimiento de preparacion de disacaridos".Info
- Publication number
- ES8303444A1 ES8303444A1 ES512381A ES512381A ES8303444A1 ES 8303444 A1 ES8303444 A1 ES 8303444A1 ES 512381 A ES512381 A ES 512381A ES 512381 A ES512381 A ES 512381A ES 8303444 A1 ES8303444 A1 ES 8303444A1
- Authority
- ES
- Spain
- Prior art keywords
- disaccharides
- uronic
- glucosamine
- units
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000002016 disaccharides Chemical class 0.000 title abstract 2
- MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 title 1
- MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 title 1
- 229960002442 glucosamine Drugs 0.000 title 1
- 125000000524 functional group Chemical group 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DISACARIDOS 1,4-ALFA CONSTITUIDOS POR MOTIVOS CON ESTRUCTURA D-GLUCOSAMINA Y ACIDO GLUCURONICO, DE FORMULA (I), EN LA QUE R ES UN ALCOHILO C <- Y A, M Y Z PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE CONDENSACION ENTRE DOS MONOSACARIDOS, CUYA ESTRUCTURA Y NATURALEZA DE SUS GRUPOS REACTIVO Y DE BLOQUEO PERMITE EL ESTABLECIMIENTO DEL ENLACE 1,4 ALFA, EN CONDICIONES COMPATIBLES CON LOS SUSTITUYENTES DE LOS MONOSACARIDOS; SEGUIDA DE LA SUCESIVA INTRODUCCION DE LOS GRUPOS FUNCIONALES DESEADOS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL CONTROL DE LA COAGULACION SANGUINEA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8108472A FR2504535B1 (fr) | 1981-04-28 | 1981-04-28 | Disaccharides derives d'un acide uronique et d'une glucosamine et compositions pharmaceutiques les contenant pour le controle de la coagulation sanguine |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8303444A1 true ES8303444A1 (es) | 1983-03-01 |
ES512381A0 ES512381A0 (es) | 1983-03-01 |
Family
ID=9257873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512381A Granted ES512381A0 (es) | 1981-04-28 | 1982-04-28 | "procedimiento de preparacion de disacaridos". |
Country Status (11)
Country | Link |
---|---|
US (2) | US4607025A (es) |
EP (1) | EP0064012B1 (es) |
JP (1) | JPS58500564A (es) |
AT (1) | ATE20894T1 (es) |
AU (1) | AU558472B2 (es) |
CA (1) | CA1263381A (es) |
DE (1) | DE3272110D1 (es) |
ES (1) | ES512381A0 (es) |
FR (1) | FR2504535B1 (es) |
SU (1) | SU1470196A3 (es) |
WO (1) | WO1982003863A1 (es) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2504535B1 (fr) * | 1981-04-28 | 1987-08-14 | Choay Sa | Disaccharides derives d'un acide uronique et d'une glucosamine et compositions pharmaceutiques les contenant pour le controle de la coagulation sanguine |
US4818816A (en) * | 1981-04-28 | 1989-04-04 | Choay, S.A. | Process for the organic synthesis of oligosaccharides and derivatives thereof |
FR2535324A1 (fr) * | 1982-10-27 | 1984-05-04 | Choay Sa | Station perfectionnee pour l'epuration d'eaux usees |
CA1247608A (fr) * | 1981-12-23 | 1988-12-28 | Jean Choay | Derives a structure acide uronique, leur preparation et leurs applications biologiques |
FR2535323B1 (fr) * | 1982-10-27 | 1987-08-14 | Choay Sa | Nouveaux derives a structure acide uronique, leur preparation et leurs applications biologiques |
CA1265132A (en) * | 1982-01-15 | 1990-01-30 | Mahmoud Nassr | Process for the organic synthesis of oligosaccharides and derivatives thereof |
AU563351C (en) * | 1982-01-15 | 2003-06-19 | Glaxo Group Limited | Synthesis of oligosaccharides |
US4847338A (en) * | 1985-03-28 | 1989-07-11 | University Of Iowa Research Foundation | Low molecular weight heparin fragments as inhibitors of complement activation |
US4916219A (en) * | 1985-03-28 | 1990-04-10 | University Of Iowa Research Foundation | Oligosaccharide heparin fragments as inhibitors of complement cascade |
GB8519416D0 (en) * | 1985-08-01 | 1985-09-04 | Unilever Plc | Oligosaccharides |
DE3602670A1 (de) * | 1986-01-29 | 1987-07-30 | Speck Ulrich | Verwendung von n-acetylglucosamin zur therapie degenerativer gelenkprozesse und verwandter erkrankungen |
GB8630720D0 (en) * | 1986-12-23 | 1987-02-04 | Unilever Plc | Cosmetic compositions |
GB8630721D0 (en) * | 1986-12-23 | 1987-02-04 | Unilever Plc | Cosmetic compositions |
NL8701342A (nl) * | 1987-06-09 | 1989-01-02 | Tno | Bifunctionele oligosacchariden alsmede daarvan afgeleide aktieve verbindingen. |
US5344870A (en) * | 1987-12-02 | 1994-09-06 | Alberta Research Council | Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation |
US5079353A (en) * | 1987-12-02 | 1992-01-07 | Chembiomed, Ltd. | Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation |
IT1217458B (it) * | 1988-05-02 | 1990-03-22 | Crinos Ind Farmacoriologica S | Sulfoamino derivati di condroitin solfati,del dermatan solfato e dell' acido ialuronico e loro proprieta' farmacologiche |
JPH0296588A (ja) * | 1988-09-29 | 1990-04-09 | Rikagaku Kenkyusho | 硫酸化オリゴ糖及びその関連物質 |
US5141928B1 (en) * | 1989-12-20 | 1995-11-14 | Brujo Inc | Ophthalmic medication |
LU87766A1 (fr) * | 1990-07-20 | 1992-03-11 | Oreal | Utilisation de derives de pyrimidine 3-oxyde pour freiner la chute des cheveux et compositions topiques mises en oeuvre |
GB2286193A (en) * | 1991-03-28 | 1995-08-09 | Italfarmaco Spa | Anticoagulants and processes for preparing such |
FR2677884B1 (fr) * | 1991-06-20 | 1993-07-09 | Oreal | Composition pour freiner la chute des cheveux a base de pyrimidines n-oxyde trisubstitues ou leurs derives sulfoconjugues, nouveaux composes pyrimidines n-oxyde ou leurs derives sulfoconjugues. |
US5336765A (en) * | 1991-12-31 | 1994-08-09 | Lever Brothers Company, Division Of Conopco, Inc. | Process of preparing N-substituted aldobionamides |
US5296588A (en) * | 1991-12-31 | 1994-03-22 | Lever Brothers Company, Division Of Conopco, Inc. | Process of preparing N-substituted aldonamides |
US6750207B1 (en) * | 1992-05-01 | 2004-06-15 | Yeda Research And Development Co. Ltd. | Compositions for the regulation of cytokine activity |
US5861382A (en) * | 1992-05-01 | 1999-01-19 | Yeda Research And Development Co. Ltd. | Methods for regulation of active TNF-α |
IL105011A (en) * | 1992-05-22 | 1997-07-13 | Japan Res Dev Corp | Disaccharides, process for the preparation thereof from plants and their use |
US5696100A (en) * | 1992-12-22 | 1997-12-09 | Glycomed Incorporated | Method for controlling O-desulfation of heparin and compositions produced thereby |
US5401839A (en) * | 1993-03-23 | 1995-03-28 | Lever Brothers Company, Division Of Conopco, Inc. | Process of preparing N-substituted aldonamides having improved color and color stability |
US5646130A (en) * | 1995-06-30 | 1997-07-08 | Ocean University Of Oingdao | Low molecular weight sulfated polysaccharides and uses thereof |
US5750665A (en) * | 1995-10-04 | 1998-05-12 | Vosika; Gerald J. | Preparation of glucosaminyl muramic acid derivatives |
US7390668B2 (en) * | 1996-10-30 | 2008-06-24 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for photodynamic treatment of disease |
CA2377734A1 (en) * | 1999-06-30 | 2001-01-11 | Hamilton Civic Hospitals Research Development, Inc. | Heparin compositions that inhibit clot associated coagulation factors |
KR20030069990A (ko) * | 2000-09-08 | 2003-08-27 | 해밀톤 시빅 호스피탈즈 리서치 디벨로프먼트 인코포레이티드 | 항혈전 조성물 |
US6592985B2 (en) * | 2000-09-20 | 2003-07-15 | Camco International (Uk) Limited | Polycrystalline diamond partially depleted of catalyzing material |
CA2806561C (en) | 2001-09-07 | 2015-12-22 | Alchemia Limited | Synthetic heparin pentasaccharides |
US7285536B2 (en) * | 2001-12-05 | 2007-10-23 | Yeda Research And Development Co., Ltd. | Anti-cancer therapeutic compounds |
JP5041664B2 (ja) | 2002-06-21 | 2012-10-03 | ロレアル | 脱毛症を治療するためのタウリンの利用 |
WO2008059307A2 (en) * | 2006-11-16 | 2008-05-22 | Om Pharma | Functionalized beta 1,6 glucosamine disaccharides and process for their preparation |
KR101529061B1 (ko) | 2008-05-30 | 2015-06-16 | 모멘타 파머슈티컬스 인코포레이티드 | 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법 |
CN104245718B (zh) * | 2009-07-31 | 2016-11-09 | 可靠生物医药公司 | 制备磺达肝素钠的方法及其合成中使用的中间体 |
ES2358829B1 (es) | 2009-10-23 | 2012-06-25 | Lipotec, S.A. | Péptidos útiles en el tratamiento y/o cuidado de la piel, mucosas y/o cabello y su uso en composiciones cosméticas o farmacéuticas. |
US8420790B2 (en) | 2009-10-30 | 2013-04-16 | Reliable Biopharmaceutical Corporation | Efficient and scalable process for the manufacture of Fondaparinux sodium |
ES2373704B1 (es) | 2010-02-18 | 2013-01-24 | Lipotec S.A. | Liposomas para el tratamiento de materiales textiles. |
ES2384060B1 (es) | 2010-03-24 | 2013-09-23 | Lipotec S.A. | Cápsulas de nanopartículas lipídicas. |
ES2383271B1 (es) | 2010-03-24 | 2013-08-01 | Lipotec S.A. | Procedimiento de tratamiento de fibras y/o materiales textiles |
ES2386177B1 (es) | 2010-09-21 | 2013-09-23 | Lipotec, S.A. | Nanocapsulas conteniendo microemulsiones |
CN107108837B (zh) | 2014-10-31 | 2021-04-13 | 路博润先进材料公司 | 用于递送活性剂到皮肤表面的热塑性聚氨酯膜 |
WO2017079248A1 (en) | 2015-11-05 | 2017-05-11 | Lubrizol Advanced Materials, Inc. | Thermoformable dual network hydrogel compositions |
WO2019200027A1 (en) | 2018-04-12 | 2019-10-17 | Lubrizol Advanced Materials, Inc. | Hair modification composition and method therefor |
EP4340807A1 (en) | 2021-05-17 | 2024-03-27 | Lubrizol Advanced Materials, Inc. | Hair color compositions for mitigating color loss |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2374236A (en) * | 1943-01-23 | 1945-04-24 | Du Pont | Surface active aldoside condensation products |
US4098995A (en) * | 1976-07-12 | 1978-07-04 | American Cyanamid Company | Polygalactosido-sucrose poly(h-)sulfate salts |
US4362720A (en) * | 1977-04-14 | 1982-12-07 | Chembiomed Ltd. | Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2-deoxyglycosides from glycals |
CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
JPS5629597A (en) * | 1979-08-21 | 1981-03-24 | Seikagaku Kogyo Co Ltd | Alkyl glycoside of constituent unit disaccharide of acid mucopolysaccharide and oligosaccharide consisting of said disaccharide, and preparation thereof |
IL61201A (en) * | 1979-10-05 | 1984-09-30 | Choay Sa | Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them |
CA1171375A (en) * | 1980-09-15 | 1984-07-24 | Ulf P.F. Lindahl | Oligosaccharides having selective anticoagulation activity |
US4413120A (en) * | 1981-04-06 | 1983-11-01 | Purdue Research Foundation | Process for producing acosamine, daunosamine, 1-thioacosamine and related compounds |
FR2504535B1 (fr) * | 1981-04-28 | 1987-08-14 | Choay Sa | Disaccharides derives d'un acide uronique et d'une glucosamine et compositions pharmaceutiques les contenant pour le controle de la coagulation sanguine |
US4435387A (en) * | 1982-10-25 | 1984-03-06 | American Cyanamid Company | Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives |
-
1981
- 1981-04-28 FR FR8108472A patent/FR2504535B1/fr not_active Expired
-
1982
- 1982-04-28 DE DE8282400770T patent/DE3272110D1/de not_active Expired
- 1982-04-28 ES ES512381A patent/ES512381A0/es active Granted
- 1982-04-28 AU AU83955/82A patent/AU558472B2/en not_active Ceased
- 1982-04-28 WO PCT/FR1982/000076 patent/WO1982003863A1/en unknown
- 1982-04-28 AT AT82400770T patent/ATE20894T1/de not_active IP Right Cessation
- 1982-04-28 CA CA000401832A patent/CA1263381A/fr not_active Expired
- 1982-04-28 EP EP82400770A patent/EP0064012B1/fr not_active Expired
- 1982-04-28 JP JP57501461A patent/JPS58500564A/ja active Granted
- 1982-12-20 US US06/451,615 patent/US4607025A/en not_active Expired - Fee Related
- 1982-12-27 SU SU823528900A patent/SU1470196A3/ru active
-
1986
- 1986-07-21 US US06/888,527 patent/US4774231A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPS58500564A (ja) | 1983-04-14 |
WO1982003863A1 (en) | 1982-11-11 |
ATE20894T1 (de) | 1986-08-15 |
US4607025A (en) | 1986-08-19 |
JPH0313240B2 (es) | 1991-02-22 |
EP0064012A1 (fr) | 1982-11-03 |
AU558472B2 (en) | 1987-01-29 |
EP0064012B1 (fr) | 1986-07-23 |
AU8395582A (en) | 1982-11-24 |
SU1470196A3 (ru) | 1989-03-30 |
DE3272110D1 (en) | 1986-08-28 |
FR2504535A1 (fr) | 1982-10-29 |
ES512381A0 (es) | 1983-03-01 |
CA1263381A (fr) | 1989-11-28 |
FR2504535B1 (fr) | 1987-08-14 |
US4774231A (en) | 1988-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970303 |