ATE125550T1 - Polypeptid und verfahren zu dessen herstellung. - Google Patents

Polypeptid und verfahren zu dessen herstellung.

Info

Publication number
ATE125550T1
ATE125550T1 AT90121558T AT90121558T ATE125550T1 AT E125550 T1 ATE125550 T1 AT E125550T1 AT 90121558 T AT90121558 T AT 90121558T AT 90121558 T AT90121558 T AT 90121558T AT E125550 T1 ATE125550 T1 AT E125550T1
Authority
AT
Austria
Prior art keywords
hydrogen
hydroxy
polypeptide
production
hydroxysulfonyloxy
Prior art date
Application number
AT90121558T
Other languages
English (en)
Inventor
Toshiro Iwamoto
Akihiko Fujie
Kumiko Nitta
Yasuhisa Tsurumi
Nobuharu Shigematsu
Chiyoshi Kasahara
Motohiro Hino
Masakuni Okuhara
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE125550T1 publication Critical patent/ATE125550T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Stringed Musical Instruments (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Materials For Medical Uses (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90121558T 1989-11-13 1990-11-10 Polypeptid und verfahren zu dessen herstellung. ATE125550T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898925593A GB8925593D0 (en) 1989-11-13 1989-11-13 Fr901379 substance and preparation thereof

Publications (1)

Publication Number Publication Date
ATE125550T1 true ATE125550T1 (de) 1995-08-15

Family

ID=10666207

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90121558T ATE125550T1 (de) 1989-11-13 1990-11-10 Polypeptid und verfahren zu dessen herstellung.

Country Status (19)

Country Link
US (1) US5502033A (de)
EP (1) EP0431350B1 (de)
JP (1) JP3111470B2 (de)
KR (1) KR910009729A (de)
CN (1) CN1051757A (de)
AT (1) ATE125550T1 (de)
AU (1) AU6655790A (de)
CA (1) CA2029766A1 (de)
DE (1) DE69021176T2 (de)
DK (1) DK0431350T3 (de)
ES (1) ES2075115T3 (de)
FI (1) FI905575A0 (de)
GB (1) GB8925593D0 (de)
HU (1) HUT58820A (de)
IE (1) IE904072A1 (de)
IL (1) IL96272A0 (de)
NO (1) NO904904L (de)
PT (1) PT95876A (de)
ZA (1) ZA908892B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
IE990233A1 (en) * 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof
US5428009A (en) * 1990-07-16 1995-06-27 Merck & Co., Inc. Lipopeptide derivatives
USH1638H (en) * 1990-11-08 1997-03-04 Furuta; Takahisa Use of the polypeptide compound
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii
US5385884A (en) * 1991-08-27 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
IL109615A (en) * 1993-05-17 2000-12-06 Fujisawa Pharmaceutical Co Cyclic polypeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
EP0805685B1 (de) * 1995-01-26 2001-09-26 Merck & Co., Inc. Neue fungizide cyclohexapeptide
EP0885957B1 (de) 1996-03-08 2009-08-12 Astellas Pharma Inc. Prozess für die deacylierung von zyklischen lipopeptiden.
EP0933422A4 (de) * 1996-06-13 2005-02-02 Fujisawa Pharmaceutical Co Zyclische lipopeptid acylase
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO691897A0 (en) * 1997-05-21 1997-06-12 Fujisawa Pharmaceutical Co., Ltd. New compound
US6319757B1 (en) * 1998-07-08 2001-11-20 Caldus Semiconductor, Inc. Adhesion and/or encapsulation of silicon carbide-based semiconductor devices on ceramic substrates
AU2001265039B2 (en) * 2000-05-26 2007-03-29 Board Of Trustees Of The University Of Illinois Reagents and methods for identifying and modulating expression of genes regulated by retinoids
JP2004524318A (ja) * 2001-02-26 2004-08-12 藤沢薬品工業株式会社 エチノカンジン誘導体およびその医薬組成物および医薬としての用途
AUPS188302A0 (en) * 2002-04-22 2002-05-30 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
US20100256048A1 (en) 2007-10-29 2010-10-07 Astellas Pharma Inc. Polypeptide compound
PL2261238T3 (pl) * 2008-03-14 2014-10-31 Astellas Pharma Inc Związek cykliczny i jego sól
CA2813330A1 (en) 2010-09-29 2012-04-05 Shanghai Techwell Biopharmaceutical Co., Ltd. Process for purifying cyclolipopeptide compounds or the salts thereof
EP2623611B1 (de) * 2010-09-30 2016-07-13 Shanghai Techwell Biopharmaceutical Co., Ltd Verfahren zur reinigung eines zyklischen lipopeptids oder eines salzes davon
CN102485879A (zh) * 2010-12-03 2012-06-06 上海医药工业研究院 一种用于生产wf11899a的发酵培养基
CN102533551B (zh) * 2010-12-15 2013-10-09 上海天伟生物制药有限公司 一种肽类抗生素的高产菌株及其制备方法和用途
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
CN102952179B (zh) * 2011-08-24 2015-11-25 华北制药集团新药研究开发有限责任公司 一种高纯度米卡芬净前体化合物的制备方法
CN102659930B (zh) 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627689B (zh) 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN103387975A (zh) 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途
CN103848900B (zh) * 2012-12-04 2015-12-02 上海医药工业研究院 一种从发酵液中分离纯化wf11899a的方法
CN114874919B (zh) * 2022-05-09 2023-06-27 中国科学院青岛生物能源与过程研究所 一株米卡芬净前体fr901379高产菌株及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4287120A (en) * 1979-12-13 1981-09-01 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4322338A (en) * 1979-12-13 1982-03-30 Eli Lilly And Company Derivatives of A-30912B nucleus
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
US4320052A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
US4320053A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912D nucleus
EP0311193B1 (de) * 1987-10-07 1993-12-01 Merck & Co. Inc. Fungizides Fermentationsprodukt
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IE990233A1 (en) * 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof

Also Published As

Publication number Publication date
ES2075115T3 (es) 1995-10-01
HU907105D0 (en) 1991-05-28
US5502033A (en) 1996-03-26
IL96272A0 (en) 1991-08-16
HUT58820A (en) 1992-03-30
IE904072A1 (en) 1991-05-22
PT95876A (pt) 1991-09-13
JPH03184921A (ja) 1991-08-12
EP0431350A1 (de) 1991-06-12
EP0431350B1 (de) 1995-07-26
KR910009729A (ko) 1991-06-28
DK0431350T3 (da) 1995-09-11
CN1051757A (zh) 1991-05-29
AU6655790A (en) 1991-05-16
DE69021176T2 (de) 1996-01-11
GB8925593D0 (en) 1990-01-04
FI905575A0 (fi) 1990-11-12
CA2029766A1 (en) 1991-05-14
DE69021176D1 (de) 1995-08-31
JP3111470B2 (ja) 2000-11-20
ZA908892B (en) 1991-09-25
NO904904D0 (no) 1990-11-12
NO904904L (no) 1991-05-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee