DK0805685T3 - Hidtil ukendte antifungale cyclohexapeptider - Google Patents

Hidtil ukendte antifungale cyclohexapeptider

Info

Publication number
DK0805685T3
DK0805685T3 DK96908446T DK96908446T DK0805685T3 DK 0805685 T3 DK0805685 T3 DK 0805685T3 DK 96908446 T DK96908446 T DK 96908446T DK 96908446 T DK96908446 T DK 96908446T DK 0805685 T3 DK0805685 T3 DK 0805685T3
Authority
DK
Denmark
Prior art keywords
cyclohexapeptides
new antifungal
compounds
antifungal
carba
Prior art date
Application number
DK96908446T
Other languages
English (en)
Inventor
Frances A Bouffard
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0805685T3 publication Critical patent/DK0805685T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DK96908446T 1995-01-26 1996-01-22 Hidtil ukendte antifungale cyclohexapeptider DK0805685T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37868795A 1995-01-26 1995-01-26
PCT/US1996/000921 WO1996022784A1 (en) 1995-01-26 1996-01-22 Novel antifungal cyclohexapeptides

Publications (1)

Publication Number Publication Date
DK0805685T3 true DK0805685T3 (da) 2001-11-19

Family

ID=23494135

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96908446T DK0805685T3 (da) 1995-01-26 1996-01-22 Hidtil ukendte antifungale cyclohexapeptider

Country Status (11)

Country Link
US (1) US5854213A (da)
EP (1) EP0805685B1 (da)
JP (1) JP2966936B2 (da)
AT (1) ATE206054T1 (da)
AU (1) AU691743B2 (da)
CA (1) CA2211138A1 (da)
DE (1) DE69615535T2 (da)
DK (1) DK0805685T3 (da)
ES (1) ES2162039T3 (da)
PT (1) PT805685E (da)
WO (1) WO1996022784A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA72200C2 (uk) 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
FR2772028B1 (fr) * 1997-12-10 2000-02-04 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
WO2000076556A2 (en) 1999-06-11 2000-12-21 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
CA2380176A1 (en) * 1999-07-27 2001-02-01 Aventis Pharma Deutschland Gmbh Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical
WO2001052894A2 (en) * 2000-01-20 2001-07-26 Basilea Pharmaceutica Ag Nasally administrable cyclic peptide compositions
AU2002249935A1 (en) 2001-01-08 2002-08-19 Neorx Corporation Radioactively labelled conjugates of phosphonates
US6914045B2 (en) * 2001-04-25 2005-07-05 Wyeth Holdings Corporation Glycopeptide antibiotics
AU2002303480A1 (en) * 2001-04-25 2002-11-05 Wyeth Holdings Corporation Glycopeptide antibiotics
JP2005516933A (ja) 2001-12-13 2005-06-09 ダウ グローバル テクノロジーズ インコーポレイティド 放射性医薬による骨髄炎の治療
KR101331984B1 (ko) 2010-12-09 2013-11-25 종근당바이오 주식회사 카스포펀진 제조방법 및 그의 신규 중간체
JP5809296B2 (ja) 2011-03-03 2015-11-10 シーチェイド ファーマシューティカルズ，インコーポレーテッド 抗真菌薬及びそれらの使用
ES2957620T3 (es) 2012-03-19 2024-01-23 Cidara Therapeutics Inc Regímenes de dosificación para los compuestos de la clase de las equinocandinas
CN108883152A (zh) 2016-01-08 2018-11-23 奇达拉治疗公司 防止和治疗肺孢子虫感染的方法
MA43825A (fr) 2016-03-16 2021-04-07 Cidara Therapeutics Inc Schémas posologiques pour le traitement d'infections fongiques
JP2020529973A (ja) 2017-07-12 2020-10-15 シダラ セラピューティクス インコーポレーテッド 真菌感染症の処置のための組成物及び方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE851310A (fr) * 1976-02-12 1977-08-10 Sandoz Sa Nouveaux derives de la tetrahydro-equinocandine b
DE2742435A1 (de) * 1976-09-28 1978-04-06 Sandoz Ag Aminoalkylaether der peptide tetrahydro- sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
US5202309A (en) 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
US5194377A (en) 1989-06-30 1993-03-16 Merck & Co., Inc. Antibiotic agent
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Peptides, of antibiotics, processes for their preparation and pharmaceutical preparations containing them
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii
US6030944A (en) * 1991-10-01 2000-02-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compounds
IL105048A (en) * 1992-03-19 2001-06-14 Eli Lilly And Company U S Antifungal substances of the cyclic peptide type and a process for their preparation
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US6268338B1 (en) * 1993-04-30 2001-07-31 Merck & Co., Inc. Cyclohexapeptidyl amine compounds
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds

Also Published As

Publication number Publication date
AU691743B2 (en) 1998-05-21
ATE206054T1 (de) 2001-10-15
JP2966936B2 (ja) 1999-10-25
ES2162039T3 (es) 2001-12-16
DE69615535T2 (de) 2002-05-02
EP0805685B1 (en) 2001-09-26
DE69615535D1 (de) 2001-10-31
US5854213A (en) 1998-12-29
JPH10505100A (ja) 1998-05-19
CA2211138A1 (en) 1996-08-01
WO1996022784A1 (en) 1996-08-01
AU5168196A (en) 1996-08-14
EP0805685A1 (en) 1997-11-12
EP0805685A4 (en) 1998-04-29
PT805685E (pt) 2002-02-28

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