NO174200C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-imino-6-polyfluoralkoksybenzotiazol-forbindelser - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-imino-6-polyfluoralkoksybenzotiazol-forbindelser

Info

Publication number
NO174200C
NO174200C NO895031A NO895031A NO174200C NO 174200 C NO174200 C NO 174200C NO 895031 A NO895031 A NO 895031A NO 895031 A NO895031 A NO 895031A NO 174200 C NO174200 C NO 174200C
Authority
NO
Norway
Prior art keywords
polyfluoroalkoxybenzothiazole
imino
compounds
therapeutically active
analogous process
Prior art date
Application number
NO895031A
Other languages
English (en)
Norwegian (no)
Other versions
NO174200B (no
NO895031L (no
NO895031D0 (no
Inventor
Francois Audiau
Claude Gueremy
Patrick Jimonet
Serge Mignani
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816547A external-priority patent/FR2640623B1/fr
Priority claimed from FR8909482A external-priority patent/FR2649703B1/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of NO895031D0 publication Critical patent/NO895031D0/no
Publication of NO895031L publication Critical patent/NO895031L/no
Publication of NO174200B publication Critical patent/NO174200B/no
Publication of NO174200C publication Critical patent/NO174200C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO895031A 1988-12-15 1989-12-14 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-imino-6-polyfluoralkoksybenzotiazol-forbindelser NO174200C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816547A FR2640623B1 (fr) 1988-12-15 1988-12-15 Derives de la benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR8909482A FR2649703B1 (fr) 1989-07-13 1989-07-13 Derives d'imino-2 polyfluoroalcoxy-6 benzothiazole, leurs procedes de preparation et les medicaments les contenant

Publications (4)

Publication Number Publication Date
NO895031D0 NO895031D0 (no) 1989-12-14
NO895031L NO895031L (no) 1990-06-18
NO174200B NO174200B (no) 1993-12-20
NO174200C true NO174200C (no) 1994-04-06

Family

ID=26227050

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895031A NO174200C (no) 1988-12-15 1989-12-14 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-imino-6-polyfluoralkoksybenzotiazol-forbindelser

Country Status (12)

Country Link
US (2) US4980356A (pt)
EP (1) EP0375510B1 (pt)
JP (1) JPH0733377B2 (pt)
CA (1) CA2005591A1 (pt)
DE (1) DE68903484T2 (pt)
DK (1) DK169921B1 (pt)
ES (1) ES2052954T3 (pt)
FI (1) FI93107C (pt)
GR (1) GR3006372T3 (pt)
IE (1) IE62406B1 (pt)
NO (1) NO174200C (pt)
PT (1) PT92605B (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US6413948B1 (en) 1996-09-27 2002-07-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of effecting a neuronal activity in an animal using naaladase inhibitors

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE102612T1 (de) * 1989-07-13 1994-03-15 Rhone Poulenc Sante 2-imino-3 heterocyclylamino-benzothiazoline, ihre herstellung und sie enthaltende arzneimittel.
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
US5240948A (en) * 1989-12-13 1993-08-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2688138B1 (fr) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.
DE10232440B4 (de) 2002-06-28 2018-06-07 Zf Friedrichshafen Ag Antriebssystem für ein Fahrzeug
AU2015269198B2 (en) * 2014-06-06 2020-12-10 The Scripps Research Institute Sulfur(VI) fluoride compounds and methods for the preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US5985855A (en) 1996-09-27 1999-11-16 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using NAALADase inhibitors
US6004946A (en) 1996-09-27 1999-12-21 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US6413948B1 (en) 1996-09-27 2002-07-02 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of effecting a neuronal activity in an animal using naaladase inhibitors

Also Published As

Publication number Publication date
DK633789D0 (da) 1989-12-14
IE894007L (en) 1990-06-15
US5026717A (en) 1991-06-25
ES2052954T3 (es) 1994-07-16
PT92605A (pt) 1990-06-29
JPH02223570A (ja) 1990-09-05
FI895982A0 (fi) 1989-12-14
CA2005591A1 (fr) 1990-06-15
GR3006372T3 (pt) 1993-06-21
NO174200B (no) 1993-12-20
JPH0733377B2 (ja) 1995-04-12
EP0375510A1 (fr) 1990-06-27
DE68903484D1 (de) 1992-12-17
FI93107C (fi) 1995-02-27
NO895031L (no) 1990-06-18
US4980356A (en) 1990-12-25
DK633789A (da) 1990-06-16
IE62406B1 (en) 1995-01-25
FI93107B (fi) 1994-11-15
PT92605B (pt) 1995-09-12
DE68903484T2 (de) 1993-03-18
DK169921B1 (da) 1995-04-03
EP0375510B1 (fr) 1992-11-11
NO895031D0 (no) 1989-12-14

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