FI93107B - Menetelmä lääkeaineina käyttökelpoisten 2-imino-6-polyfluorialkoksibentsotiatsolijohdannaisten valmistamiseksi - Google Patents

Menetelmä lääkeaineina käyttökelpoisten 2-imino-6-polyfluorialkoksibentsotiatsolijohdannaisten valmistamiseksi

Info

Publication number
FI93107B
FI93107B FI895982A FI895982A FI93107B FI 93107 B FI93107 B FI 93107B FI 895982 A FI895982 A FI 895982A FI 895982 A FI895982 A FI 895982A FI 93107 B FI93107 B FI 93107B
Authority
FI
Finland
Prior art keywords
polyfluoroalkoxybenzothiazole
imino
drug
preparation
derivatives useful
Prior art date
Application number
FI895982A
Other languages
English (en)
Swedish (sv)
Other versions
FI895982A0 (fi
FI93107C (fi
Inventor
Francois Audiau
Claude Gueremy
Patrick Jimonet
Serge Mignani
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816547A external-priority patent/FR2640623B1/fr
Priority claimed from FR8909482A external-priority patent/FR2649703B1/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of FI895982A0 publication Critical patent/FI895982A0/fi
Publication of FI93107B publication Critical patent/FI93107B/fi
Application granted granted Critical
Publication of FI93107C publication Critical patent/FI93107C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI895982A 1988-12-15 1989-12-14 Menetelmä lääkeaineina käyttökelpoisten 2-imino-6-polyfluorialkoksibentsotiatsolijohdannaisten valmistamiseksi FI93107C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8816547 1988-12-15
FR8816547A FR2640623B1 (fr) 1988-12-15 1988-12-15 Derives de la benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR8909482A FR2649703B1 (fr) 1989-07-13 1989-07-13 Derives d'imino-2 polyfluoroalcoxy-6 benzothiazole, leurs procedes de preparation et les medicaments les contenant
FR8909482 1989-07-13

Publications (3)

Publication Number Publication Date
FI895982A0 FI895982A0 (fi) 1989-12-14
FI93107B true FI93107B (fi) 1994-11-15
FI93107C FI93107C (fi) 1995-02-27

Family

ID=26227050

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895982A FI93107C (fi) 1988-12-15 1989-12-14 Menetelmä lääkeaineina käyttökelpoisten 2-imino-6-polyfluorialkoksibentsotiatsolijohdannaisten valmistamiseksi

Country Status (12)

Country Link
US (2) US4980356A (fi)
EP (1) EP0375510B1 (fi)
JP (1) JPH0733377B2 (fi)
CA (1) CA2005591A1 (fi)
DE (1) DE68903484T2 (fi)
DK (1) DK169921B1 (fi)
ES (1) ES2052954T3 (fi)
FI (1) FI93107C (fi)
GR (1) GR3006372T3 (fi)
IE (1) IE62406B1 (fi)
NO (1) NO174200C (fi)
PT (1) PT92605B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
DK0409692T3 (da) * 1989-07-13 1994-04-05 Rhone Poulenc Sante Derivater af 2-imino-3-heterocycloalkylbenzothiazolin, deres fremstilling og lægemidler med indhold deraf
US5240948A (en) * 1989-12-13 1993-08-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2688138B1 (fr) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
CZ60499A3 (cs) 1996-09-27 1999-08-11 Guilford Pharmaceuticals Inc. Prostředky s účinkem na NAALADázy, způsoby léčení glutamátové abnormality a způsoby ovlivňování neuronální aktivity u živočichů
DE10232440B4 (de) 2002-06-28 2018-06-07 Zf Friedrichshafen Ag Antriebssystem für ein Fahrzeug
AU2015269198B2 (en) * 2014-06-06 2020-12-10 The Scripps Research Institute Sulfur(VI) fluoride compounds and methods for the preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi

Also Published As

Publication number Publication date
NO895031L (no) 1990-06-18
NO174200B (no) 1993-12-20
PT92605A (pt) 1990-06-29
FI895982A0 (fi) 1989-12-14
DK633789A (da) 1990-06-16
FI93107C (fi) 1995-02-27
DE68903484D1 (de) 1992-12-17
IE894007L (en) 1990-06-15
NO895031D0 (no) 1989-12-14
JPH0733377B2 (ja) 1995-04-12
NO174200C (no) 1994-04-06
CA2005591A1 (fr) 1990-06-15
DE68903484T2 (de) 1993-03-18
IE62406B1 (en) 1995-01-25
US5026717A (en) 1991-06-25
EP0375510A1 (fr) 1990-06-27
GR3006372T3 (fi) 1993-06-21
DK633789D0 (da) 1989-12-14
US4980356A (en) 1990-12-25
EP0375510B1 (fr) 1992-11-11
JPH02223570A (ja) 1990-09-05
ES2052954T3 (es) 1994-07-16
DK169921B1 (da) 1995-04-03
PT92605B (pt) 1995-09-12

Similar Documents

Publication Publication Date Title
FI891021A0 (fi) Menetelmä lääkeaineina käyttökelpoisten 1,2,4-triatsolijohdannaisten valmistamiseksi
FI871294A0 (fi) Menetelmä lääkeaineina käyttökelpoisten milbemysiinin johdannaisten valmistamiseksi
FI98196B (fi) Menetelmä mikroemulsion käsittävän farmaseuttisen formulaation valmistamiseksi
FI881978A0 (fi) Menetelmä eperisonia sisältävän farmaseuttisen koostumuksen valmistamiseksi
FI871492A0 (fi) Menetelmä lääkeaineina käyttökelpoisten 2-tiometyyli-substituoitujen 1,4-dihydropyridiinien valmistamiseksi
FI890282A (fi) Menetelmä terapeuttisesti käyttökelpoisten 23,24-didehydro-25-hydroksikalsiferolijohdannaisten valmistamiseksi
FI892640A0 (fi) Menetelmä piperidinoalkanoli-ibuprofeeniyhdistelmää sisältävän farmaseuttisen koostumuksen valmistamiseksi
FI92934B (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-deoksinojirimysiinijohdannaisten valmistamiseksi
FI881103A (fi) Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
FI891538A0 (fi) Menetelmä farmaseuttisesti käyttökelpoisten fenolisubstituoitujen gem-difosfonaattijohdannaisten valmistamiseksi
FI96029B (fi) Analogiamenetelmä lääkeaineena käyttökelpoisen pyridiinijohdannaisen valmistamiseksi
FI885884A0 (fi) Menetelmä hitaasti vapautuvan farmaseuttisen koostumuksen valmistamiseksi
FI892182A (fi) Menetelmä terapeuttisesti käyttökelpoisten kromaanijohdannaisten valmistamiseksi
FI893297A (fi) Menetelmä lääkeaineina käyttökelpoisten (atsa)naftaleenisultaamijohdannaisten valmistamiseksi
FI890283A (fi) Menetelmä terapeuttisesti käyttökelpoisten 25-hydroksi-vitamiinin D-johdannaisten valmistamiseksi
FI93106C (fi) Menetelmä lääkeaineina käyttökelpoisten 2-iminobentsotiatsoliinijohdannaisten valmistamiseksi
NO174766C (no) Fremgangsmåte til fremstilling av en doseringsenhet for kontrollert administrering av diltiazem
FI93107B (fi) Menetelmä lääkeaineina käyttökelpoisten 2-imino-6-polyfluorialkoksibentsotiatsolijohdannaisten valmistamiseksi
FI892948A (fi) Menetelmä terapeuttisesti käyttökelpoisten kromaanijohdannaisten valmistamiseksi
FI92065C (fi) Menetelmä farmaseuttisten piperidiinijohdannaisten valmistamiseksi
FI895983A0 (fi) Menetelmä lääkeaineina käyttökelpoisten 2-bentsotiatsoliinijohdannaisten valmistamiseksi
FI903077A0 (fi) Menetelmä valmistaa terapeuttisesti aktiivisia R(-)-3-kinuklidinolijohdannaisia
PT88681A (pt) A process for the preparation of pharmaceutical compositions containing piperidinoalkanol derivatives
FI900145A0 (fi) Menetelmä farmaseuttisesti käyttökelpoisten 1,1-diokso-kefem-4-karbotiolihappojohdannaisten valmistamiseksi
FI901606A0 (fi) Tieno-triatsolo-diatsepiinien sulfonyylijohdosten valmistusmenetelmä

Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: RHONE-POULENC SANTE