NO167738C - Analogifremgangsmaate ved fremstilling av heksacykliske forbindelser. - Google Patents
Analogifremgangsmaate ved fremstilling av heksacykliske forbindelser.Info
- Publication number
- NO167738C NO167738C NO882785A NO882785A NO167738C NO 167738 C NO167738 C NO 167738C NO 882785 A NO882785 A NO 882785A NO 882785 A NO882785 A NO 882785A NO 167738 C NO167738 C NO 167738C
- Authority
- NO
- Norway
- Prior art keywords
- compound
- preparation
- analogy procedure
- hexacyclic compounds
- hexacyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Lubricants (AREA)
- Fats And Perfumes (AREA)
- Liquid Crystal Substances (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15699087 | 1987-06-24 | ||
| JP550388 | 1988-01-13 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO882785D0 NO882785D0 (no) | 1988-06-23 |
| NO882785L NO882785L (no) | 1988-12-27 |
| NO167738B NO167738B (no) | 1991-08-26 |
| NO167738C true NO167738C (no) | 1991-12-04 |
Family
ID=26339454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO882785A NO167738C (no) | 1987-06-24 | 1988-06-23 | Analogifremgangsmaate ved fremstilling av heksacykliske forbindelser. |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US4939255A (no) |
| EP (1) | EP0296597B1 (no) |
| KR (1) | KR960002853B1 (no) |
| AT (1) | ATE111913T1 (no) |
| AU (1) | AU610189B2 (no) |
| CA (1) | CA1304370C (no) |
| DE (1) | DE3851577T2 (no) |
| DK (1) | DK344488A (no) |
| ES (1) | ES2064329T3 (no) |
| FI (1) | FI91872C (no) |
| IE (1) | IE61281B1 (no) |
| NO (1) | NO167738C (no) |
| PH (1) | PH27557A (no) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4939255A (en) * | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| US5552154A (en) * | 1989-11-06 | 1996-09-03 | The Stehlin Foundation For Cancer Research | Method for treating cancer with water-insoluble s-camptothecin of the closed lactone ring form and derivatives thereof |
| US5637770A (en) * | 1991-01-16 | 1997-06-10 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic compound |
| US6407115B1 (en) * | 1991-01-16 | 2002-06-18 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic compound |
| JP3008226B2 (ja) * | 1991-01-16 | 2000-02-14 | 第一製薬株式会社 | 六環性化合物 |
| US6080751A (en) * | 1992-01-14 | 2000-06-27 | The Stehlin Foundation For Cancer Research | Method for treating pancreatic cancer in humans with water-insoluble S-camptothecin of the closed lactone ring form and derivatives thereof |
| US5446047A (en) * | 1992-07-23 | 1995-08-29 | Sloan-Kettering Institute For Cancer Research | Camptothecin analogues |
| US5391745A (en) * | 1992-07-23 | 1995-02-21 | Sloan-Kettering Institute For Cancer Research | Methods of preparation of camptothecin analogs |
| US6504029B1 (en) * | 1995-04-10 | 2003-01-07 | Daiichi Pharmaceutical Co., Ltd. | Condensed-hexacyclic compounds and a process therefor |
| US5663177A (en) * | 1995-05-31 | 1997-09-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs |
| US5670500A (en) * | 1995-05-31 | 1997-09-23 | Smithkline Beecham Corporation | Water soluble camptothecin analogs |
| CA2223484A1 (en) * | 1995-06-07 | 1996-12-19 | Thomas Jefferson University | Anti-fungal agents and methods of identifying and using the same |
| SG50747A1 (en) * | 1995-08-02 | 1998-07-20 | Tanabe Seiyaku Co | Comptothecin derivatives |
| SG103322A1 (en) | 1996-10-30 | 2004-04-29 | Tanabe Seiyaku Co | S type 2-substituted hydroxy-2-indolidinylbutyric ester compounds and process for preparation thereof |
| KR19980076076A (ko) * | 1997-04-04 | 1998-11-16 | 유현식 | 전선용 발포성 수지조성물 |
| US6046209A (en) * | 1997-05-27 | 2000-04-04 | Smithkline Beecham Corporation | Water soluble camptothecin analogs |
| IN189180B (no) * | 1997-07-09 | 2003-01-04 | Chong Kun Dang Corp | |
| JP4094710B2 (ja) | 1997-11-06 | 2008-06-04 | 株式会社ヤクルト本社 | 新規なカンプトテシン誘導体 |
| EP2266607A3 (en) | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunoconjugates for treating cancer |
| FR2801309B1 (fr) * | 1999-11-18 | 2002-01-04 | Adir | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| RS51051B (sr) * | 2001-11-30 | 2010-10-31 | Chugai Seiyaku Kabushiki Kaisha | Heksaciklična jedinjenja |
| US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| WO2004073601A2 (en) * | 2003-02-21 | 2004-09-02 | Chugai Seiyaku Kabushiki Kaisha | Process for the preparation of hexacyclic camptothecin derivatives |
| BRPI0509732A (pt) | 2004-04-09 | 2007-09-25 | Chugai Pharmaceutical Co Ltd | pró-fármaco solúvel em água, composição farmacêutica, agente terapêutico, agente antifungo e uso do referido pró-fármaco |
| TW200744603A (en) | 2005-08-22 | 2007-12-16 | Chugai Pharmaceutical Co Ltd | Novel anticancer concomitant drug |
| CN102060713A (zh) * | 2010-12-09 | 2011-05-18 | 中华人民共和国嘉兴出入境检验检疫局 | 用于检测偶氮类染料的芳香胺半抗原及其制备方法 |
| CA3133757A1 (en) | 2019-03-29 | 2020-10-08 | Medimmune Limited | Compounds and conjugates thereof |
| WO2021148500A1 (en) | 2020-01-22 | 2021-07-29 | Medimmune Limited | Compounds and conjugates thereof |
| TW202140076A (zh) | 2020-01-22 | 2021-11-01 | 英商梅迪繆思有限公司 | 化合物及其軛合物 |
| US11806405B1 (en) | 2021-07-19 | 2023-11-07 | Zeno Management, Inc. | Immunoconjugates and methods |
| MX2024011518A (es) | 2022-03-23 | 2024-09-24 | Synaffix Bv | Conjugados de anticuerpos para el tratamiento de tumores que expresan ptk7. |
| WO2023180490A1 (en) | 2022-03-23 | 2023-09-28 | Synaffix B.V. | Antibody-conjugates for targeting of tumours expressing nectin-4 |
| CN119212731A (zh) | 2022-03-23 | 2024-12-27 | 新锐生物技术公司 | 用于靶向表达Trop-2的肿瘤的抗体缀合物 |
| WO2023180489A1 (en) | 2022-03-23 | 2023-09-28 | Synaffix B.V. | Antibody-conjugates for targeting of tumours expressing carcinoembyronic antigen |
| WO2024140933A1 (zh) * | 2022-12-30 | 2024-07-04 | 长春金赛药业有限责任公司 | 喜树碱衍生物、药物组合物及其制备方法和应用 |
| WO2024235105A1 (en) * | 2023-05-12 | 2024-11-21 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Linker compounds and ligand-drug conjugates, preparation methods and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US32518A (en) * | 1861-06-11 | Improvement in city railroads | ||
| JPS51288A (ja) * | 1974-06-18 | 1976-01-05 | Tamura Seisakusho Kk | Hanshakyoshinhoshasochi |
| US4399282A (en) * | 1979-07-10 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives |
| US4399276A (en) * | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
| JPS5839685A (ja) * | 1981-09-04 | 1983-03-08 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体及びその製造法 |
| US4473692A (en) * | 1981-09-04 | 1984-09-25 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
| JPS58154582A (ja) * | 1982-03-10 | 1983-09-14 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体およびその製造法 |
| JPS6019790A (ja) * | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| EP0220601B1 (en) * | 1985-10-21 | 1991-12-11 | Daiichi Seiyaku Co., Ltd. | Pyranoindolizine derivatives and preparation process thereof |
| US4939255A (en) * | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| US5004758A (en) * | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
| JPH0615547B2 (ja) * | 1988-01-20 | 1994-03-02 | 株式会社ヤクルト本社 | 新規なカンプトテシン誘導体 |
-
1988
- 1988-06-16 US US07/207,718 patent/US4939255A/en not_active Expired - Fee Related
- 1988-06-20 IE IE186088A patent/IE61281B1/en not_active IP Right Cessation
- 1988-06-21 CA CA000569969A patent/CA1304370C/en not_active Expired - Lifetime
- 1988-06-23 DE DE3851577T patent/DE3851577T2/de not_active Expired - Fee Related
- 1988-06-23 ES ES88110044T patent/ES2064329T3/es not_active Expired - Lifetime
- 1988-06-23 FI FI883050A patent/FI91872C/fi not_active IP Right Cessation
- 1988-06-23 EP EP88110044A patent/EP0296597B1/en not_active Expired - Lifetime
- 1988-06-23 AT AT88110044T patent/ATE111913T1/de not_active IP Right Cessation
- 1988-06-23 DK DK344488A patent/DK344488A/da not_active Application Discontinuation
- 1988-06-23 NO NO882785A patent/NO167738C/no unknown
- 1988-06-24 KR KR1019880007643A patent/KR960002853B1/ko not_active IP Right Cessation
- 1988-06-24 AU AU18349/88A patent/AU610189B2/en not_active Ceased
- 1988-07-22 PH PH37104A patent/PH27557A/en unknown
-
1989
- 1989-12-27 US US07/457,921 patent/US5061795A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU1834988A (en) | 1989-01-05 |
| NO882785D0 (no) | 1988-06-23 |
| EP0296597A2 (en) | 1988-12-28 |
| KR890000489A (ko) | 1989-03-15 |
| CA1304370C (en) | 1992-06-30 |
| KR960002853B1 (ko) | 1996-02-27 |
| EP0296597B1 (en) | 1994-09-21 |
| ES2064329T3 (es) | 1995-02-01 |
| US4939255A (en) | 1990-07-03 |
| PH27557A (en) | 1993-08-18 |
| DK344488A (da) | 1989-02-24 |
| NO882785L (no) | 1988-12-27 |
| DE3851577D1 (de) | 1994-10-27 |
| US5061795A (en) | 1991-10-29 |
| EP0296597A3 (en) | 1991-07-31 |
| FI883050A0 (fi) | 1988-06-23 |
| IE881860L (en) | 1988-12-24 |
| FI91872B (fi) | 1994-05-13 |
| NO167738B (no) | 1991-08-26 |
| DE3851577T2 (de) | 1995-04-27 |
| FI883050A (fi) | 1988-12-25 |
| ATE111913T1 (de) | 1994-10-15 |
| FI91872C (fi) | 1994-08-25 |
| AU610189B2 (en) | 1991-05-16 |
| DK344488D0 (da) | 1988-06-23 |
| IE61281B1 (en) | 1994-10-19 |
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