NO166939C - Analogifremgangsmaate for fremstilling av terapeutisk aktive carboxylsyrederivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive carboxylsyrederivater.

Info

Publication number
NO166939C
NO166939C NO871059A NO871059A NO166939C NO 166939 C NO166939 C NO 166939C NO 871059 A NO871059 A NO 871059A NO 871059 A NO871059 A NO 871059A NO 166939 C NO166939 C NO 166939C
Authority
NO
Norway
Prior art keywords
carboxylic acid
acid derivatives
preparation
pct
therapeutic active
Prior art date
Application number
NO871059A
Other languages
English (en)
Other versions
NO871059D0 (no
NO166939B (no
NO871059L (no
Inventor
Hans Peter Wolff
Ernst-Christian Witte
Hans-Frieder Kuehnle
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO871059D0 publication Critical patent/NO871059D0/no
Publication of NO871059L publication Critical patent/NO871059L/no
Publication of NO166939B publication Critical patent/NO166939B/no
Publication of NO166939C publication Critical patent/NO166939C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/88Unsaturated compounds containing keto groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
NO871059A 1985-07-16 1987-03-13 Analogifremgangsmaate for fremstilling av terapeutisk aktive carboxylsyrederivater. NO166939C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853525284 DE3525284A1 (de) 1985-07-16 1985-07-16 Neue carbonsaeurederivate, verfahren zu ihrer herstellung, ihre verwendung sowie arzneimittel, die diese verbindungen enthalten
PCT/EP1986/000406 WO1987000521A2 (en) 1985-07-16 1986-07-10 New carboxylic acid derivatives, their manufacturing process, use and medicines containing these compounds

Publications (4)

Publication Number Publication Date
NO871059D0 NO871059D0 (no) 1987-03-13
NO871059L NO871059L (no) 1987-03-13
NO166939B NO166939B (no) 1991-06-10
NO166939C true NO166939C (no) 1991-09-18

Family

ID=6275845

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871059A NO166939C (no) 1985-07-16 1987-03-13 Analogifremgangsmaate for fremstilling av terapeutisk aktive carboxylsyrederivater.

Country Status (21)

Country Link
US (1) US4933367A (no)
EP (1) EP0226636B1 (no)
JP (1) JPS63500310A (no)
KR (1) KR870700599A (no)
AT (1) ATE40681T1 (no)
AU (2) AU595814B2 (no)
CA (1) CA1316922C (no)
DD (1) DD254193A5 (no)
DE (2) DE3525284A1 (no)
DK (1) DK100487A (no)
ES (1) ES2001163A6 (no)
FI (1) FI871143A (no)
GR (1) GR861803B (no)
IL (1) IL79379A0 (no)
NO (1) NO166939C (no)
NZ (1) NZ216830A (no)
PH (1) PH25313A (no)
PT (1) PT82987B (no)
SU (1) SU1708156A3 (no)
WO (1) WO1987000521A2 (no)
ZA (1) ZA865192B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910002674B1 (ko) * 1986-05-29 1991-05-03 이 아이 듀우판 디 네모아 앤드 캄파니 실릴케텐 아세탈의 아실화
DE3700729A1 (de) * 1987-01-13 1988-07-21 Boehringer Mannheim Gmbh Neue carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE3935512A1 (de) * 1989-10-25 1991-05-02 Boehringer Mannheim Gmbh Neues herstellungsverfahren fuer verbindungen mit wertvollen pharmakologischen eigenschaften sowie neue zwischenprodukte zur herstellung dieser verbindungen
DE4112103C2 (de) * 1991-02-18 1994-07-14 Matthias Mueller Verwendung von Essigsäure zur Regulierung der Blutzuckerwerte
JP2785162B2 (ja) * 1991-04-05 1998-08-13 富士写真フイルム株式会社 写真用ポリエステル支持体およびハロゲン化銀写真感光材料
AR002945A1 (es) * 1994-11-15 1998-05-27 Bayer Corp Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
US6172057B1 (en) 1997-02-27 2001-01-09 American Cyanamid Company N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
US6197791B1 (en) 1997-02-27 2001-03-06 American Cyanamid Company N-hdroxy-2-(alkyl, aryl, or heteroaryl, sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
US6262118B1 (en) * 1999-06-04 2001-07-17 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia
US7576131B2 (en) * 1999-06-04 2009-08-18 Metabolex, Inc. Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia
US6685951B2 (en) 2001-07-05 2004-02-03 R. T. Alamo Ventures I, Inc. Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
US20030017175A1 (en) * 2001-07-05 2003-01-23 R.T. Alamo Ventures I, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
US20030198669A1 (en) * 2001-07-05 2003-10-23 R.T. Alamo Ventures I, Llc Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
US6720450B2 (en) 2001-12-13 2004-04-13 North Carolina State University Pesticidal activity of functionalized cyclopropanes
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
EP1749000A4 (en) * 2004-05-25 2009-12-30 Metabolex Inc BICYCLIC SUBSTITUTED TRIAZOLE AS PPAR MODULATORS AND METHOD FOR THE PRODUCTION THEREOF
CN1997633A (zh) * 2004-05-25 2007-07-11 麦它波莱克斯股份有限公司 作为ppar调节剂的取代的三唑及其制备方法
US7714131B2 (en) * 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
AU2008312002A1 (en) * 2007-10-12 2009-04-23 The Government Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health& Human Services Therapeutic applications of fatty acid amide hydrolase inhibitors
CN114075106B (zh) * 2020-08-12 2023-09-12 广东省稀有金属研究所 一种脂肪醇醚羧酸的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562330A (en) 1968-07-18 1971-02-09 Parke Davis & Co 2-phenoxy-4- and 5-phenyl-butyl and -pentyl-amines and salts
BE760034A (fr) * 1969-12-08 1971-06-08 Ici Ltd Production d'esters
DE2162038A1 (de) * 1970-05-05 1972-08-17 William H Rorer Ine , Fort Washington, Pa (V St A ) Verfahren zur Herstellung von synthe tischen Alkansauren und deren Derivaten
DE3032669A1 (de) * 1979-09-07 1981-04-02 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Substituierte oxirancarbonsaeuren, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
US4933367A (en) 1990-06-12
GR861803B (en) 1986-11-10
WO1987000521A2 (en) 1987-01-29
FI871143A0 (fi) 1987-03-16
NO871059D0 (no) 1987-03-13
PT82987A (de) 1986-08-01
DD254193A5 (de) 1988-02-17
DE3525284A1 (de) 1987-01-29
AU6194286A (en) 1987-02-10
EP0226636B1 (de) 1989-02-08
FI871143A (fi) 1987-03-16
IL79379A0 (en) 1986-10-31
AU595814B2 (en) 1990-04-12
DE3662041D1 (en) 1989-03-16
PH25313A (en) 1991-04-30
ES2001163A6 (es) 1988-05-01
NO166939B (no) 1991-06-10
DK100487D0 (da) 1987-02-26
DK100487A (da) 1987-02-26
CA1316922C (en) 1993-04-27
ATE40681T1 (de) 1989-02-15
WO1987000521A3 (fr) 1987-03-12
SU1708156A3 (ru) 1992-01-23
PT82987B (pt) 1988-07-01
NO871059L (no) 1987-03-13
NZ216830A (en) 1990-11-27
AU5988086A (en) 1987-01-22
EP0226636A1 (de) 1987-07-01
ZA865192B (en) 1987-03-25
JPS63500310A (ja) 1988-02-04
KR870700599A (ko) 1987-12-30

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