NO158579C - Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-(2-metoksyetyl)-noroksymorfon. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-(2-metoksyetyl)-noroksymorfon.

Info

Publication number
NO158579C
NO158579C NO831995A NO831995A NO158579C NO 158579 C NO158579 C NO 158579C NO 831995 A NO831995 A NO 831995A NO 831995 A NO831995 A NO 831995A NO 158579 C NO158579 C NO 158579C
Authority
NO
Norway
Prior art keywords
metoxythyl
noroxymorphone
preparation
therapeutic active
analogy procedure
Prior art date
Application number
NO831995A
Other languages
English (en)
Norwegian (no)
Other versions
NO158579B (no
NO831995L (no
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO831995L publication Critical patent/NO831995L/no
Publication of NO158579B publication Critical patent/NO158579B/no
Publication of NO158579C publication Critical patent/NO158579C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO831995A 1982-06-03 1983-06-02 Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-(2-metoksyetyl)-noroksymorfon. NO158579C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823220831 DE3220831A1 (de) 1982-06-03 1982-06-03 N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (3)

Publication Number Publication Date
NO831995L NO831995L (no) 1983-12-05
NO158579B NO158579B (no) 1988-06-27
NO158579C true NO158579C (no) 1988-10-05

Family

ID=6165151

Family Applications (1)

Application Number Title Priority Date Filing Date
NO831995A NO158579C (no) 1982-06-03 1983-06-02 Analogifremgangsmaate for fremstilling av terapeutisk aktivt n-(2-metoksyetyl)-noroksymorfon.

Country Status (27)

Country Link
US (1) US4473573A (xx)
EP (1) EP0096279B1 (xx)
JP (1) JPS591487A (xx)
KR (1) KR900006754B1 (xx)
AU (1) AU558319B2 (xx)
CA (1) CA1196633A (xx)
CS (1) CS236882B2 (xx)
CZ (1) CZ410691A3 (xx)
DD (1) DD209834A5 (xx)
DE (2) DE3220831A1 (xx)
DK (1) DK156068C (xx)
ES (1) ES8403487A1 (xx)
FI (1) FI78101C (xx)
GB (1) GB2121041B (xx)
GR (1) GR78273B (xx)
HK (1) HK1389A (xx)
HU (1) HU185832B (xx)
IE (1) IE55232B1 (xx)
IL (1) IL68872A0 (xx)
NO (1) NO158579C (xx)
NZ (1) NZ204451A (xx)
PH (1) PH19518A (xx)
PL (1) PL139569B1 (xx)
PT (1) PT76805B (xx)
SG (1) SG58788G (xx)
SU (1) SU1195909A3 (xx)
ZA (1) ZA833981B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132159A1 (de) * 1991-09-27 1993-04-01 Boehringer Ingelheim Kg 14-hydroxy-n-(2-methoxyethyl)-7,8-dihydromorphin und -norisomorphin, verfahren zu deren herstellung und deren verwendung als arzneimittel
NZ600379A (en) 2009-12-04 2014-05-30 Alkermes Pharma Ireland Ltd Morphinan derivatives for the treatment of drug overdose
CA2807965C (en) 2010-08-23 2016-03-15 Alkermes Pharma Ireland Limited Methods for treating antipsychotic-induced weight gain
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
CA2911231C (en) 2013-05-24 2021-12-07 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
DE2538075A1 (de) * 1975-08-27 1977-03-17 Boehringer Sohn Ingelheim N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
HU185832B (en) 1985-04-28
JPS591487A (ja) 1984-01-06
FI78101C (fi) 1989-06-12
EP0096279B1 (de) 1985-11-06
DK250783A (da) 1983-12-04
SG58788G (en) 1989-03-10
IE831299L (en) 1983-12-03
HK1389A (en) 1989-01-13
DK156068C (da) 1989-11-06
GR78273B (xx) 1984-09-26
NZ204451A (en) 1986-07-11
PT76805B (de) 1986-04-09
CS236882B2 (en) 1985-05-15
GB2121041B (en) 1985-09-11
CA1196633A (en) 1985-11-12
PL242312A1 (en) 1985-04-09
NO158579B (no) 1988-06-27
PT76805A (de) 1983-07-01
PH19518A (en) 1986-05-14
DK250783D0 (da) 1983-06-02
FI831941A0 (fi) 1983-05-31
ES522897A0 (es) 1984-03-16
PL139569B1 (en) 1987-02-28
IE55232B1 (en) 1990-07-04
ES8403487A1 (es) 1984-03-16
IL68872A0 (en) 1983-10-31
AU1531483A (en) 1983-12-08
US4473573A (en) 1984-09-25
DD209834A5 (de) 1984-05-23
GB8315292D0 (en) 1983-07-06
KR900006754B1 (ko) 1990-09-20
JPH0373552B2 (xx) 1991-11-22
AU558319B2 (en) 1987-01-29
DK156068B (da) 1989-06-19
DE3220831A1 (de) 1983-12-08
CZ410691A3 (en) 1993-02-17
GB2121041A (en) 1983-12-14
EP0096279A1 (de) 1983-12-21
SU1195909A3 (ru) 1985-11-30
KR840005146A (ko) 1984-11-03
DE3361165D1 (en) 1985-12-12
FI831941L (fi) 1983-12-04
FI78101B (fi) 1989-02-28
NO831995L (no) 1983-12-05
ZA833981B (en) 1985-01-30

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