NO156525C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive (3-aminopropoksy)bibenzylderivater. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive (3-aminopropoksy)bibenzylderivater.

Info

Publication number
NO156525C
NO156525C NO822833A NO822833A NO156525C NO 156525 C NO156525 C NO 156525C NO 822833 A NO822833 A NO 822833A NO 822833 A NO822833 A NO 822833A NO 156525 C NO156525 C NO 156525C
Authority
NO
Norway
Prior art keywords
aminopropoxy
preparation
therapeutic active
analogy procedure
bibenzyl
Prior art date
Application number
NO822833A
Other languages
English (en)
Norwegian (no)
Other versions
NO822833L (no
NO156525B (no
Inventor
Ryoji Kikumoto
Harukazi Fukami
Hiroto Hara
Kunihiro Ninomiya
Mamoru Sugano
Original Assignee
Mitsubishi Chem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15040620&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO156525(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Chem Ind filed Critical Mitsubishi Chem Ind
Publication of NO822833L publication Critical patent/NO822833L/no
Publication of NO156525B publication Critical patent/NO156525B/no
Publication of NO156525C publication Critical patent/NO156525C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO822833A 1981-08-20 1982-08-19 Analogifremgangsmaate ved fremstilling av terapeutisk aktive (3-aminopropoksy)bibenzylderivater. NO156525C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56130704A JPS5832847A (ja) 1981-08-20 1981-08-20 （３−アミノプロポキシ）ビベンジル類

Publications (3)

Publication Number Publication Date
NO822833L NO822833L (no) 1983-02-21
NO156525B NO156525B (no) 1987-06-29
NO156525C true NO156525C (no) 1987-10-07

Family

ID=15040620

Family Applications (1)

Application Number Title Priority Date Filing Date
NO822833A NO156525C (no) 1981-08-20 1982-08-19 Analogifremgangsmaate ved fremstilling av terapeutisk aktive (3-aminopropoksy)bibenzylderivater.

Country Status (9)

Country Link
US (2) US4485258A (fr)
EP (1) EP0072942B1 (fr)
JP (1) JPS5832847A (fr)
CA (1) CA1193264A (fr)
DD (1) DD202531A5 (fr)
DE (1) DE3275540D1 (fr)
DK (1) DK166381C (fr)
HU (1) HU186560B (fr)
NO (1) NO156525C (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5832847A (ja) * 1981-08-20 1983-02-25 Mitsubishi Chem Ind Ltd （３−アミノプロポキシ）ビベンジル類
US4616017A (en) * 1984-06-04 1986-10-07 Merck & Co., Inc. Aminohydroxypropoxy substituted aryl compounds
JPH02304022A (ja) * 1989-05-18 1990-12-17 Mitsubishi Kasei Corp セロトニン拮抗剤
TW385302B (en) * 1992-11-30 2000-03-21 Sankyo Co Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis
JP4063341B2 (ja) * 1994-07-06 2008-03-19 メイ株式会社 緑内障治療剤及び眼圧降下剤
DE69710258T2 (de) * 1996-06-17 2002-08-22 Mitsubishi Chem Corp Mittel zur Beschleunigung des Tränenflusses enthaltend einen Serotonin-Liganden, insbesondere Aminoalkoxybibenzyle
US6468998B1 (en) 1998-11-02 2002-10-22 Mitsubishi Pharma Corporation Pyrrolidine compounds and medicinal utilization thereof
US20040242687A1 (en) * 2001-09-26 2004-12-02 Yoshikazu Kobayashi Thrombus/thrombogenesis inhibitors
CN1824647B (zh) * 2005-02-22 2011-04-20 田边三菱制药株式会社 (±)2-(二甲基氨基)-1-{[O-(m-甲氧基苯乙基)苯氧基]甲基}乙基氢琥珀酸酯盐酸盐的晶体
JP2006160764A (ja) * 2005-02-22 2006-06-22 Mitsubishi Pharma Corp （±）２−（ジメチルアミノ）−１−｛〔Ｏ−（ｍ−メトキシフェネチル）フェノキシ〕メチル｝エチル水素サクシナート塩酸塩の結晶
KR101393178B1 (ko) * 2005-02-22 2014-05-08 미쓰비시 타나베 파마 코퍼레이션 (±)2-(디메틸아미노)-1-｛[Ｏ-(ｍ-메톡시페네틸)페녹시]메틸｝에틸 수소 숙시네이트 염산염의 결정
NZ562765A (en) 2005-06-03 2009-12-24 Rheon Automatic Machinery Co Rotating conical rollers spread dough into a disc shape
CN101239920B (zh) * 2007-02-05 2013-05-22 南京康然医药科技有限公司 一种盐酸沙格雷酯的制备方法
JP5090770B2 (ja) * 2007-04-06 2012-12-05 ダイト株式会社 塩酸サルポグレラートの工業的製造方法
KR100881890B1 (ko) 2007-05-03 2009-02-04 주식회사 엔지켐 사포그렐레이트 염산염의 제조방법
CN101854929A (zh) * 2007-11-09 2010-10-06 田边三菱制药株式会社 新型制剂
JP5116025B2 (ja) 2008-01-21 2013-01-09 レオン自動機株式会社 食品生地延展成形装置および食品生地延展成形方法
KR20100050371A (ko) * 2008-11-10 2010-05-13 주식회사 참조아 염산((±)-２-(디메칠아미노)-１-[[ｏ-(ｍ-메톡시펜에틸)페녹시]메틸]에틸하이드로겐 숙시네이트의 신규 결정 및 이 신규결정을 유효성분으로 함유하는 의약조성물
KR100911720B1 (ko) 2009-04-10 2009-08-10 주식회사 한서켐 결정형 염산 사포그릴레이트의 제조방법
KR101653816B1 (ko) 2014-06-25 2016-09-06 주식회사 대희화학 결정형 사포그릴레이트 옥살산염 일수화물 또는 이의 무수물
CN104356012B (zh) * 2014-09-23 2016-06-15 山东齐都药业有限公司 盐酸沙格雷酯光降解杂质的制备方法
KR101905865B1 (ko) 2017-04-11 2018-10-08 아주대학교산학협력단 사포그릴레이트를 유효성분으로 포함하는 감각신경성 난청의 예방 또는 치료용 조성물

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301580A (fr) * 1962-12-11
DE2001431C3 (de) * 1970-01-06 1974-12-12 Helopharm W. Petrik & Co Kg, 1000 Berlin 2-(2'-Hydroxy-3'-alkylaminopropoxy)-Omega-phenyl-propiophenone und Verfahren zur Herstellung derselben
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
GB1486001A (en) * 1974-07-30 1977-09-14 Beecham Group Ltd 7-aminoalkoxy substituted benzopyrans benzo thiopyrans and naphthalenes
GB1493998A (en) * 1975-06-03 1977-12-07 Beecham Group Ltd Propanolamine derivatives
US4071552A (en) * 1976-05-19 1978-01-31 Ayerst Mckenna And Harrison Ltd. Aryloxy aminobutanols, their preparation and use thereof
JPS5365836A (en) * 1976-11-26 1978-06-12 Teijin Ltd Preparation of aminopropanol derivs. or their salts
US4220603A (en) * 1977-10-07 1980-09-02 Mitsubishi Chemical Industries, Limited Pharmaceutically active (omega-aminoalkoxy)bibenzyls
JPS6045632B2 (ja) * 1978-03-09 1985-10-11 三菱化学株式会社 ω−アミノアルコキシスチルベン類及びその酸付加塩
JPS5531136A (en) * 1978-08-25 1980-03-05 Hitachi Metals Ltd Fe-cr-co type magnet alloy
JPS5629550A (en) * 1979-08-18 1981-03-24 Tsutomu Kunishige Novel preparation of 1-aryloxy-3-isopropylaminopropan-2-ol
JPS5629549A (en) * 1979-08-18 1981-03-24 Tsutomu Kunishige Preparation of 1-aryloxy-3-isopropylaminopropan-2-ol
JPS56123954A (en) * 1980-03-05 1981-09-29 Sagami Chem Res Center Preparation of aminoalcohol derivative
JPS5770844A (en) * 1980-10-20 1982-05-01 Paamakemu Asia:Kk Preparation of aminopropanol derivative
JPS5832847A (ja) * 1981-08-20 1983-02-25 Mitsubishi Chem Ind Ltd （３−アミノプロポキシ）ビベンジル類
JPS6123954A (ja) * 1984-07-12 1986-02-01 Hitachi Ltd Ｎｍｒイメ−ジング装置

Also Published As

Publication number Publication date
JPS5832847A (ja) 1983-02-25
EP0072942A2 (fr) 1983-03-02
DK166381C (da) 1993-09-27
US4599419A (en) 1986-07-08
US4485258A (en) 1984-11-27
EP0072942B1 (fr) 1987-03-04
CA1193264A (fr) 1985-09-10
DE3275540D1 (en) 1987-04-09
HU186560B (en) 1985-08-28
DK365682A (da) 1983-02-21
JPS6313427B2 (fr) 1988-03-25
NO822833L (no) 1983-02-21
EP0072942A3 (en) 1984-06-06
DK166381B (da) 1993-05-10
DD202531A5 (de) 1983-09-21
NO156525B (no) 1987-06-29

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