NO155133C - Analogifremgangsmaate for fremstilling av terapeutisk virksomme dicykliske forbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme dicykliske forbindelser.

Info

Publication number
NO155133C
NO155133C NO813662A NO813662A NO155133C NO 155133 C NO155133 C NO 155133C NO 813662 A NO813662 A NO 813662A NO 813662 A NO813662 A NO 813662A NO 155133 C NO155133 C NO 155133C
Authority
NO
Norway
Prior art keywords
dicyclic
relations
preparation
therapeutically effective
analogy procedure
Prior art date
Application number
NO813662A
Other languages
English (en)
Norwegian (no)
Other versions
NO813662L (no
NO155133B (no
Inventor
Yoshikazu Oka
Kohei Nishikawa
Akio Miyake
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP55154394A external-priority patent/JPS5777651A/ja
Priority claimed from JP56064371A external-priority patent/JPS57179141A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO813662L publication Critical patent/NO813662L/no
Priority to NO862859A priority Critical patent/NO157103C/no
Publication of NO155133B publication Critical patent/NO155133B/no
Publication of NO155133C publication Critical patent/NO155133C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO813662A 1980-10-31 1981-10-29 Analogifremgangsmaate for fremstilling av terapeutisk virksomme dicykliske forbindelser. NO155133C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO862859A NO157103C (no) 1980-10-31 1986-07-15 Analogifremgangsmÿte for fremstilling av terapeutisk virksomme dicykliske forbindelser.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55154394A JPS5777651A (en) 1980-10-31 1980-10-31 Indane derivative and its preparation
JP56064371A JPS57179141A (en) 1981-04-28 1981-04-28 Bicyclic compound and its preparation

Publications (3)

Publication Number Publication Date
NO813662L NO813662L (no) 1982-05-03
NO155133B NO155133B (no) 1986-11-10
NO155133C true NO155133C (no) 1987-02-18

Family

ID=26405485

Family Applications (1)

Application Number Title Priority Date Filing Date
NO813662A NO155133C (no) 1980-10-31 1981-10-29 Analogifremgangsmaate for fremstilling av terapeutisk virksomme dicykliske forbindelser.

Country Status (19)

Country Link
US (3) US4822818A (fr)
EP (1) EP0051391B1 (fr)
KR (1) KR880000890B1 (fr)
AU (1) AU543804B2 (fr)
CA (1) CA1287444C (fr)
DE (1) DE3165862D1 (fr)
DK (1) DK164917C (fr)
ES (3) ES8306710A1 (fr)
FI (1) FI73698C (fr)
GB (1) GB2086393B (fr)
GR (1) GR75368B (fr)
HK (1) HK19887A (fr)
HU (1) HU183652B (fr)
IE (1) IE51918B1 (fr)
MY (1) MY8500500A (fr)
NO (1) NO155133C (fr)
NZ (1) NZ198826A (fr)
PH (2) PH18357A (fr)
PT (1) PT73912B (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4906615A (en) * 1980-12-18 1990-03-06 Schering Corporation Substituted dipeptides as inhibitors of enkephalinases
US4610816A (en) * 1980-12-18 1986-09-09 Schering Corporation Substituted dipeptides as inhibitors of enkephalinases
AT387717B (de) * 1983-03-16 1989-03-10 Immuno Ag Verfahren zum bestimmen von unvertraeglichkeitsreaktionen verursachenden substanzen in therapeutisch und prophylaktisch anzuwendenden blutprodukten sowie verwendung des verfahrens
US4666906A (en) * 1983-03-16 1987-05-19 Usv Pharmaceutical Corporation Compounds for treating hypertension
US4596791A (en) * 1983-03-16 1986-06-24 Usv Pharmaceutical Corp. Compounds for treating hypertension
US4564612A (en) * 1983-04-22 1986-01-14 Takeda Chemical Industries, Ltd. Condensed, seven-membered ring compounds and their use
IL72523A (en) * 1983-08-12 1988-06-30 Takeda Chemical Industries Ltd 3-amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine derivatives,their production and pharmaceutical compositions containing them
US4638000A (en) * 1983-08-12 1987-01-20 Takeda Chemical Industries, Ltd. Condensed seven-membered ring compounds, their production and use
GB8414987D0 (en) * 1984-06-12 1984-07-18 Beecham Group Plc Active compounds
EP0187037A3 (fr) * 1984-12-21 1988-03-23 Takeda Chemical Industries, Ltd. Dérivés de pipéridine, leur production et emploi
JPS64100A (en) * 1987-03-04 1989-01-05 Takeda Chem Ind Ltd Production of indane derivative
EP0284510A3 (fr) * 1987-03-24 1990-08-22 Asahi Breweries, Ltd. N-[N alpha-(1(S)-carboxy-3-cyclohexylpropyl)-L-lysyl]-N-cyclopentylglycine en tant qu'antihypertenseurs
US4956490A (en) * 1989-03-09 1990-09-11 Merck & Co., Inc. Process for preparing benzylpyruvic acids and esters
IT1232160B (it) * 1989-07-31 1992-01-25 Sigma Tau Ind Farmaceuti 2-(n-acil)ammino-6,7-dimetossi tetraline, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' antiipertensiva che le contengono
DE4021108A1 (de) * 1990-07-03 1992-01-09 Bayer Ag Optisch aktive n-(alpha)-fluoracryloyl-aminosaeure-derivate, ihre herstellung, die daraus hergestellten optisch aktiven polymeren und deren verwendung zur spaltung von racematen
DE4123248C2 (de) * 1991-07-13 1996-03-07 Degussa Verfahren zur Herstellung von N-substituierten alpha-Aminosäuren und alpha-Aminosäure-Derivaten
US5977160A (en) * 1992-04-10 1999-11-02 Brigham And Women's Hospital, Inc. Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
KR20030046079A (ko) * 2001-12-05 2003-06-12 주식회사 코오롱 고순도 염산 델라프릴의 신규한 정제방법
NZ543789A (en) * 2003-04-30 2008-03-28 Wellstat Therapeutics Corp Compounds for the treatment of metabolic disorders
KR20110117731A (ko) * 2003-05-30 2011-10-27 랜박시 래보러터리스 리미티드 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도
AU2006313430B2 (en) * 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
WO2008020314A2 (fr) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Formulations de dosage stabilisantes à base de statine
ITMI20061364A1 (it) * 2006-07-13 2008-01-14 Dipharma Spa Procedimento per la preparazione di delapril
WO2008010087A2 (fr) * 2006-07-14 2008-01-24 Ranbaxy Laboratories Limited FORMES POLYMORPHES D'UN INHIBITEUR DE LA HMG-CoA-RÉDUCTASE ET LEURS UTILISATIONS
WO2014202659A1 (fr) 2013-06-21 2014-12-24 Sanofi-Aventis Deutschland Gmbh Procédé de préparation d'amides de n-[1-(s)-(éthoxycarbonyl)-3-phénylpropyl]-l-alanine
CA3218884A1 (fr) * 2021-05-11 2022-11-17 David Nutt Composes et compositions therapeutiques a base d'aminoindane

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension
IT1105731B (it) * 1977-06-29 1985-11-04 Yoshitomi Pharmaceutical Composti di tiazolidina
LU78804A1 (de) * 1977-12-30 1979-07-20 Byk Gulden Lomberg Chem Fab N-substituierte w-aminoalkanoyl-w-aminoalkansaeuren,ihre verwendung und verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4243678A (en) * 1977-12-30 1981-01-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Acylhydrocarbylaminoalkanoic acids, compositions and uses
US4316896A (en) * 1978-09-07 1982-02-23 Merck & Co., Inc. Aminoacid derivatives as antihypertensives
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
DE3040021A1 (de) * 1980-10-23 1982-05-13 Windmöller & Hölscher, 4540 Lengerich Vorrichtung zum bilden und stapeln von von einer folienschlauchbahn abgetrennten abschnitten
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids

Also Published As

Publication number Publication date
AU543804B2 (en) 1985-05-02
PH21390A (en) 1987-10-15
GB2086393A (en) 1982-05-12
ES506714A0 (es) 1983-06-01
PH18357A (en) 1985-06-05
KR880000890B1 (ko) 1988-05-30
GR75368B (fr) 1984-07-13
DK478181A (da) 1982-05-01
GB2086393B (en) 1984-01-11
IE51918B1 (en) 1987-04-29
MY8500500A (en) 1985-12-31
IE812471L (en) 1982-04-30
US4822818A (en) 1989-04-18
US4474692A (en) 1984-10-02
NZ198826A (en) 1984-07-06
FI73698B (fi) 1987-07-31
NO813662L (no) 1982-05-03
DK164917C (da) 1993-02-01
DK164917B (da) 1992-09-07
ES524148A0 (es) 1985-05-01
FI813383L (fi) 1982-05-01
HK19887A (en) 1987-03-13
ES8401445A1 (es) 1983-12-01
AU7652181A (en) 1982-05-06
PT73912A (en) 1981-11-01
ES8306710A1 (es) 1983-06-01
CA1287444C (fr) 1991-08-06
NO155133B (no) 1986-11-10
FI73698C (fi) 1987-11-09
EP0051391B1 (fr) 1984-09-05
EP0051391A1 (fr) 1982-05-12
ES515269A0 (es) 1983-12-01
KR830007514A (ko) 1983-10-21
ES8504671A1 (es) 1985-05-01
US5098892A (en) 1992-03-24
HU183652B (en) 1984-05-28
PT73912B (en) 1983-01-25
DE3165862D1 (en) 1984-10-11

Similar Documents

Publication Publication Date Title
NO155133C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme dicykliske forbindelser.
NO163691C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive n-acryl-piperazinalkanamider.
NO160368C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive bicykliske azoforbindelser.
NO159531C (no) Analogifremgangsmaate for fremstilling av farmasoeytisk aktive karbostyrilderivater.
NO156864C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive piperinderivater.
NO159667C (no) Fremgangsmaate for fremstilling av kikhostetoksid.
NO162858C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive thiazolidinderivater.
NO158060C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonforbindelser.
NO158183C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolylfenylamidiner.
NO154492C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme forbindelser.
NO152255C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazolylvinylethere
NO165842C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
NO812519L (no) Fremgangsmaate for fremstilling av kolesterase.
NO156865C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazolderivater.
NO158673C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive azurenderivater.
NO812701L (no) Fremgangsmaate for fremstilling av antibakterielle timetyl-cefalosporiner.
NO151196C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme fluorerte alkenylendiaminderivater
NO158376C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme rooperolforbindelser.
NO160512C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.
NO155539C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme isokinolinderivater.
NO154052C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolon-derivater.
NO157736C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme imidazolderivater.
NO159798C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cefalosporin-oksyder.
NO157934C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive antracyklinglykosider.
NO160203C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme fenotiazin-forbindelser.