NO148375C - Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-klor-7-alfa-amino-acylcefalosporinforbindelser - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-klor-7-alfa-amino-acylcefalosporinforbindelser

Info

Publication number
NO148375C
NO148375C NO740606A NO740606A NO148375C NO 148375 C NO148375 C NO 148375C NO 740606 A NO740606 A NO 740606A NO 740606 A NO740606 A NO 740606A NO 148375 C NO148375 C NO 148375C
Authority
NO
Norway
Prior art keywords
acylcephalosporine
alfa
chloro
amino
preparation
Prior art date
Application number
NO740606A
Other languages
English (en)
Norwegian (no)
Other versions
NO740606L (no
NO148375B (no
Inventor
Robert Raymond Chauvette
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO740606L publication Critical patent/NO740606L/no
Publication of NO148375B publication Critical patent/NO148375B/no
Publication of NO148375C publication Critical patent/NO148375C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO740606A 1973-02-23 1974-02-22 Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-klor-7-alfa-amino-acylcefalosporinforbindelser NO148375C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33538173A 1973-02-23 1973-02-23

Publications (3)

Publication Number Publication Date
NO740606L NO740606L (no) 1974-08-26
NO148375B NO148375B (no) 1983-06-20
NO148375C true NO148375C (no) 1983-09-28

Family

ID=23311540

Family Applications (2)

Application Number Title Priority Date Filing Date
NO740606A NO148375C (no) 1973-02-23 1974-02-22 Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-klor-7-alfa-amino-acylcefalosporinforbindelser
NO792681A NO148377C (no) 1973-02-23 1979-08-16 3-klor-7-alfa-amino-acylcefalosporinforbindelser for anvendelse som mellomprodukter ved fremstilling av terapeutisk virksomme cefalosporinderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO792681A NO148377C (no) 1973-02-23 1979-08-16 3-klor-7-alfa-amino-acylcefalosporinforbindelser for anvendelse som mellomprodukter ved fremstilling av terapeutisk virksomme cefalosporinderivater

Country Status (37)

Country Link
JP (4) JPS6139313B2 (nl)
AR (1) AR199510A1 (nl)
AT (1) AT333953B (nl)
BE (1) BE811495A (nl)
BR (1) BR7401384D0 (nl)
CA (1) CA1016537A (nl)
CH (1) CH593988A5 (nl)
CS (1) CS187409B2 (nl)
CY (1) CY1043A (nl)
DD (1) DD110278A5 (nl)
DE (1) DE2408698C2 (nl)
DK (1) DK153157C (nl)
EG (1) EG11104A (nl)
ES (1) ES423531A1 (nl)
FI (1) FI63035C (nl)
FR (1) FR2218877B1 (nl)
GB (1) GB1461323A (nl)
GT (1) GT197432133A (nl)
HK (1) HK20080A (nl)
HU (1) HU166849B (nl)
IE (1) IE39046B1 (nl)
IL (1) IL44262A (nl)
IN (1) IN139620B (nl)
KE (1) KE3027A (nl)
MW (1) MW674A1 (nl)
MY (1) MY8100024A (nl)
NL (1) NL179057C (nl)
NO (2) NO148375C (nl)
OA (1) OA04809A (nl)
PH (1) PH9616A (nl)
PL (1) PL88702B1 (nl)
RO (1) RO64663A (nl)
SE (1) SE411212B (nl)
SU (1) SU676166A3 (nl)
YU (1) YU36970B (nl)
ZA (1) ZA741191B (nl)
ZM (1) ZM3574A1 (nl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
CH619233A5 (nl) * 1975-07-31 1980-09-15 Ciba Geigy Ag
CH622802A5 (nl) * 1975-08-20 1981-04-30 Ciba Geigy Ag
IE45158B1 (en) * 1976-08-16 1982-06-30 Lilly Co Eli 3-chloro-cephem synthesis
DE3508258A1 (de) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln
DE3509618A1 (de) * 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel
JPS6436445U (nl) * 1987-08-28 1989-03-06
DE3803169A1 (de) 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
ES2010075A6 (es) * 1989-01-10 1989-10-16 Antibioticos Sa Un procedimiento para la preparacion de compuestos de 3-cloro-cefem.
JP2539459Y2 (ja) * 1991-12-18 1997-06-25 三重ホーロー株式会社 組立式塵芥焼却器
IT1255458B (it) * 1992-05-11 1995-11-02 Col Marco Da Procedimento per la preparazione di derivati beta-lattamici alogenati
ES2079327B1 (es) 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
CN101805357B (zh) * 2010-04-28 2012-01-11 陶灵刚 一种头孢克洛化合物及其制法
CN103588790A (zh) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 7-氨基-3-氯-3-头孢-4-羧酸-对硝基苄基酯的制备方法
CN106632400A (zh) * 2016-12-16 2017-05-10 石家庄柏奇化工有限公司 Pd‑C催化氢化脱除4‑硝基苄基制备7‑ACCA的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
FR2143211B1 (nl) * 1971-06-24 1975-10-31 Fujisawa Pharmaceutical Co
AR206201A1 (es) * 1972-06-29 1976-07-07 Ciba Geigy Ag Procedimiento para la obtencion de compuestos de acido 7beta-amino-3-cefem-3-01-4-carboxilico0-substituidos

Also Published As

Publication number Publication date
NO148377B (no) 1983-06-20
SE411212B (sv) 1979-12-10
DE2408698C2 (de) 1983-11-10
ATA142574A (de) 1976-04-15
YU39974A (en) 1982-06-18
NL7402489A (nl) 1974-08-27
PH9616A (en) 1976-01-20
BE811495A (fr) 1974-08-22
AU6591674A (en) 1975-08-28
NL179057B (nl) 1986-02-03
DK153157C (da) 1988-10-31
DD110278A5 (nl) 1974-12-12
JPS56138190A (en) 1981-10-28
DK153157B (da) 1988-06-20
ZM3574A1 (en) 1975-11-21
JPS56138191A (en) 1981-10-28
GT197432133A (es) 1975-08-16
HU166849B (nl) 1975-06-28
JPS6139313B2 (nl) 1986-09-03
EG11104A (en) 1976-12-31
OA04809A (fr) 1980-08-31
FI63035B (fi) 1982-12-31
IL44262A (en) 1977-08-31
MY8100024A (en) 1981-12-31
SU676166A3 (ru) 1979-07-25
NO740606L (no) 1974-08-26
RO64663A (fr) 1979-02-15
FR2218877A1 (nl) 1974-09-20
NO148375B (no) 1983-06-20
CA1016537A (en) 1977-08-30
CH593988A5 (nl) 1977-12-30
IE39046L (en) 1974-08-23
YU36970B (en) 1984-08-31
IE39046B1 (en) 1978-07-19
CS187409B2 (en) 1979-01-31
JPS49110689A (nl) 1974-10-22
CY1043A (en) 1980-08-01
HK20080A (en) 1980-04-25
FR2218877B1 (nl) 1977-03-11
ES423531A1 (es) 1976-05-16
PL88702B1 (nl) 1976-09-30
KE3027A (en) 1980-03-14
JPS56138192A (en) 1981-10-28
JPS6140236B2 (nl) 1986-09-08
BR7401384D0 (pt) 1974-11-05
IL44262A0 (en) 1974-05-16
ZA741191B (en) 1975-10-29
IN139620B (nl) 1976-07-10
NO148377C (no) 1983-09-28
AR199510A1 (es) 1974-09-09
DE2408698A1 (de) 1974-09-05
GB1461323A (en) 1977-01-13
JPS6140235B2 (nl) 1986-09-08
MW674A1 (en) 1975-04-09
JPS6140237B2 (nl) 1986-09-08
NO792681L (no) 1974-08-26
AT333953B (de) 1976-12-27
NL179057C (nl) 1986-07-01
FI63035C (fi) 1983-04-11

Similar Documents

Publication Publication Date Title
NO145382C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 3-amino-indazolkarboksylsyrederivater.
NO145273C (no) N-formyl-alfa-l-aspartyl-l-fenylalanin for anvendelse til fremstilling av alfa-l-aspartyl-l-fenylalaninalkylestere
NO143218C (no) Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet
NO143219C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser.
NO140854C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptid-amider
NO145056C (no) (s)-1-aryloksy-2-propanolderivater for fremstilling av terapeutisk aktive (s)-1-aryloksy-3-amino-2-propanolderivater
NO149281C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 7alfa-metoksycephalosporinderivater
NO141717C (no) Analogifremgangsmaate til fremstilling av farmakologisk aktive triazolopyridaziner
NO142174C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 1,1-diaryl-1-oksadiazol-alkylaminer
NO148375C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 3-klor-7-alfa-amino-acylcefalosporinforbindelser
NO140597C (no) Analogifremgangsmaate ved fremstillingen av terapeutisk aktive 8-azapurin-6-on-derivater
NO144926C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 1-benzazolylalkyl-4-substituerte piperidiner
NO142303C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme oksazolderivater
NO141850C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive pyrazolderivater.
NO137387C (no) Analogifremgangsm}te til fremstilling av 5-metyltiopyrimidiner med terapeutisk virkning
NO141755C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme dotriacontapeptidamider
NO146596C (no) Fremgangsmaate for fremstilling av 6-deoksytetracykliner
NO143064C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive hydroksyalkylxantiner
SE417601B (sv) Forfarande for framstellning av amidinokarbamider
NO843825L (no) Fremgangsmaate for fremstilling av 6-deoksytetracyklin
NO141208C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 2-(fenoksyalkyltio)imidazolforbindelser
SE409716B (sv) Analogiforfarande for framstellning av 11beta-alkyl-deltaŸ4-estrener
NO145383C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte indoler.
NO143499C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive indanderivater
NO148376C (no) Analogifremgangsmaate til fremstilling av terapeutisk virksomme 7-acylamino-3-halogen-cefalosporinforbindelser