NO146396C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidinderivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidinderivater.

Info

Publication number
NO146396C
NO146396C NO764370A NO764370A NO146396C NO 146396 C NO146396 C NO 146396C NO 764370 A NO764370 A NO 764370A NO 764370 A NO764370 A NO 764370A NO 146396 C NO146396 C NO 146396C
Authority
NO
Norway
Prior art keywords
preparation
pyrimidine derivatives
therapeutic active
analogy procedure
active pyrimidine
Prior art date
Application number
NO764370A
Other languages
English (en)
Norwegian (no)
Other versions
NO764370L (hu
NO146396B (no
Inventor
Thomas Henry Brown
Charon Robin Ganellin
Graham John Durant
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NO764370L publication Critical patent/NO764370L/no
Publication of NO146396B publication Critical patent/NO146396B/no
Publication of NO146396C publication Critical patent/NO146396C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO764370A 1975-12-29 1976-12-28 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidinderivater. NO146396C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5300175 1975-12-29

Publications (3)

Publication Number Publication Date
NO764370L NO764370L (hu) 1977-06-30
NO146396B NO146396B (no) 1982-06-14
NO146396C true NO146396C (no) 1982-09-22

Family

ID=10466233

Family Applications (1)

Application Number Title Priority Date Filing Date
NO764370A NO146396C (no) 1975-12-29 1976-12-28 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidinderivater.

Country Status (37)

Country Link
JP (1) JPS5283388A (hu)
AR (1) AR222290A1 (hu)
AT (1) AT360024B (hu)
AU (1) AU508123B2 (hu)
BE (1) BE849810A (hu)
BG (1) BG29722A3 (hu)
CA (1) CA1073458A (hu)
CH (1) CH631981A5 (hu)
CS (1) CS203995B2 (hu)
DD (1) DD128588A5 (hu)
DE (1) DE2658267A1 (hu)
DK (1) DK587076A (hu)
EG (1) EG12439A (hu)
ES (1) ES454656A1 (hu)
FI (1) FI62668C (hu)
FR (1) FR2336935A1 (hu)
GR (1) GR62441B (hu)
HU (1) HU175171B (hu)
IE (1) IE45082B1 (hu)
IL (1) IL51040A (hu)
IT (2) IT1124740B (hu)
LU (1) LU76481A1 (hu)
MW (1) MW5076A1 (hu)
MX (1) MX5119E (hu)
NL (1) NL7614538A (hu)
NO (1) NO146396C (hu)
NZ (1) NZ182759A (hu)
OA (1) OA05526A (hu)
PH (1) PH14723A (hu)
PL (1) PL104376B1 (hu)
PT (1) PT65949B (hu)
RO (1) RO72475A (hu)
SE (1) SE431544B (hu)
SU (1) SU791235A3 (hu)
YU (1) YU311676A (hu)
ZA (1) ZA767198B (hu)
ZM (1) ZM14376A1 (hu)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186511A (en) 1977-03-19 1980-11-14 Smith Kline French Lab 3-substituted alkylamino-6-substituted alkyl-1,2,4-triazin-5-ones and pharmaceutical compositions 3-substituted thio-1,2,4-triazin-5-ones
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
IN151188B (hu) * 1978-02-13 1983-03-05 Smith Kline French Lab
US4539207A (en) * 1978-02-13 1985-09-03 Smith Kline & French Laboratories Limited Pyrimidine compounds
AU527202B2 (en) * 1978-04-11 1983-02-24 Smith Kline & French Laboratories Limited 2-aminopyrimidones
ZA792607B (en) * 1978-05-30 1980-07-30 Smith Kline French Lab Nitro compounds
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas
US4309435A (en) 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
US4374836A (en) 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them
US4496567A (en) * 1978-11-13 1985-01-29 Smith Kline & French Laboratories Limited Phenyl alkylaminopyrimidones
US4521418A (en) * 1979-02-21 1985-06-04 Smith Kline & French Laboratories Limited Guanidinothiazolyl derivatives
US4255428A (en) 1979-03-24 1981-03-10 Smith Kline & French Laboratories Limited 5-(Hydroxypyridylalkyl)-4-pyrimidones
JPS55133379A (en) * 1979-04-05 1980-10-17 Smith Kline French Lab Pyrimidone compound
DE2962542D1 (en) * 1979-04-11 1982-06-03 Smith Kline French Lab Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them
JPS55145683A (en) * 1979-04-26 1980-11-13 Smith Kline French Lab Pyrimidone derivative
CA1155842A (en) * 1980-03-29 1983-10-25 Thomas H. Brown Compounds
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
PT75074B (en) * 1981-06-27 1986-02-26 Smith Kline French Lab Process for preparing certain pyrimidone derivatives and compositions containing them
US6417366B2 (en) * 1999-06-24 2002-07-09 Abbott Laboratories Preparation of quinoline-substituted carbonate and carbamate derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
IN146736B (hu) * 1975-10-02 1979-08-25 Smith Kline French Lab

Also Published As

Publication number Publication date
DK587076A (da) 1977-06-30
PH14723A (en) 1981-11-13
SE431544B (sv) 1984-02-13
NL7614538A (nl) 1977-07-01
DD128588A5 (de) 1977-11-30
CH631981A5 (en) 1982-09-15
NO764370L (hu) 1977-06-30
RO72475A (ro) 1982-10-26
DE2658267A1 (de) 1977-07-07
ZA767198B (en) 1977-11-30
EG12439A (en) 1979-09-30
ES454656A1 (es) 1977-11-16
NZ182759A (en) 1978-06-02
SE7614620L (sv) 1977-06-30
CS203995B2 (en) 1981-03-31
AT360024B (de) 1980-12-10
AU2097676A (en) 1978-07-06
OA05526A (fr) 1981-04-30
PT65949A (pt) 1977-01-01
ATA960876A (de) 1980-05-15
HU175171B (hu) 1980-05-28
IL51040A0 (en) 1977-02-28
BE849810A (fr) 1977-06-23
GR62441B (en) 1979-04-12
IT1124740B (it) 1986-05-14
PT65949B (pt) 1978-06-15
IL51040A (en) 1980-12-31
YU311676A (en) 1983-01-21
BG29722A3 (en) 1981-01-15
IE45082L (en) 1977-06-29
ZM14376A1 (en) 1977-08-22
IE45082B1 (en) 1982-06-16
CA1073458A (en) 1980-03-11
JPS5283388A (en) 1977-07-12
FR2336935A1 (fr) 1977-07-29
JPS6129355B2 (hu) 1986-07-05
FI62668C (fi) 1983-02-10
FR2336935B1 (hu) 1980-03-21
IT7919107A0 (it) 1979-01-05
LU76481A1 (hu) 1977-06-15
FI763664A (hu) 1977-06-30
AR222290A1 (es) 1981-05-15
SU791235A3 (ru) 1980-12-23
NO146396B (no) 1982-06-14
FI62668B (fi) 1982-10-29
PL104376B1 (pl) 1979-08-31
MX5119E (es) 1983-03-24
AU508123B2 (en) 1980-03-13
MW5076A1 (en) 1978-02-08

Similar Documents

Publication Publication Date Title
NO147243C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive ftalanderivater
NO145199C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive nortropinestere.
NO156611C (no) Analogifremgangsmaate for fremstilling av terapeutiske virksomme derivater av hydroksykarbonylfosfonsyre.
NO152899C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive glycerolderivater.
NO147450C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolonderivater
NO143219C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive forbindelser.
NO151411C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-aryloksy-2-hydroksy-3-alkylenaminopropan-derivater
NO146396C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidinderivater.
NO145379C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive n2-arylsulfonyl-l-argininamider.
NO156787C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinolonderivater.
NO145792C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive pyrimidon-derivater
NO148777C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive antrakinon-derivater
NO145842C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive indolizinderivater
NO146359C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive cyproheptadinderivater
NO154013C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive sesquiterpenderivater.
NO154054C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive hydroksypyrimidinderivater.
NO141850C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive pyrazolderivater.
NO148291C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive basisk substituerte teofyllinderivater
NO144457C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive dihydro-1,4-pyridiner
NO148488C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive acyl-benzimidazol-2-derivater
NO151660C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolderivater.
NO145163C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive antitumorglykosider
NO143903C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-fluorpyrimidin-4-on-derivater
NO152839C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyrilderivater.
NO146600C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive imidazolderivater