IL51040A - 2-heteroarylmethylthioethylamino-5-heteroarylalkylpyrimidin-4-one derivatives,process for their preparation und pharmaceutical compositions containing them - Google Patents

2-heteroarylmethylthioethylamino-5-heteroarylalkylpyrimidin-4-one derivatives,process for their preparation und pharmaceutical compositions containing them

Info

Publication number
IL51040A
IL51040A IL51040A IL5104076A IL51040A IL 51040 A IL51040 A IL 51040A IL 51040 A IL51040 A IL 51040A IL 5104076 A IL5104076 A IL 5104076A IL 51040 A IL51040 A IL 51040A
Authority
IL
Israel
Prior art keywords
heteroarylmethylthioethylamino
heteroarylalkylpyrimidin
und
derivatives
preparation
Prior art date
Application number
IL51040A
Other languages
English (en)
Other versions
IL51040A0 (en
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL51040A0 publication Critical patent/IL51040A0/xx
Publication of IL51040A publication Critical patent/IL51040A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL51040A 1975-12-29 1976-12-02 2-heteroarylmethylthioethylamino-5-heteroarylalkylpyrimidin-4-one derivatives,process for their preparation und pharmaceutical compositions containing them IL51040A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5300175 1975-12-29

Publications (2)

Publication Number Publication Date
IL51040A0 IL51040A0 (en) 1977-02-28
IL51040A true IL51040A (en) 1980-12-31

Family

ID=10466233

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51040A IL51040A (en) 1975-12-29 1976-12-02 2-heteroarylmethylthioethylamino-5-heteroarylalkylpyrimidin-4-one derivatives,process for their preparation und pharmaceutical compositions containing them

Country Status (37)

Country Link
JP (1) JPS5283388A (xx)
AR (1) AR222290A1 (xx)
AT (1) AT360024B (xx)
AU (1) AU508123B2 (xx)
BE (1) BE849810A (xx)
BG (1) BG29722A3 (xx)
CA (1) CA1073458A (xx)
CH (1) CH631981A5 (xx)
CS (1) CS203995B2 (xx)
DD (1) DD128588A5 (xx)
DE (1) DE2658267A1 (xx)
DK (1) DK587076A (xx)
EG (1) EG12439A (xx)
ES (1) ES454656A1 (xx)
FI (1) FI62668C (xx)
FR (1) FR2336935A1 (xx)
GR (1) GR62441B (xx)
HU (1) HU175171B (xx)
IE (1) IE45082B1 (xx)
IL (1) IL51040A (xx)
IT (2) IT1124740B (xx)
LU (1) LU76481A1 (xx)
MW (1) MW5076A1 (xx)
MX (1) MX5119E (xx)
NL (1) NL7614538A (xx)
NO (1) NO146396C (xx)
NZ (1) NZ182759A (xx)
OA (1) OA05526A (xx)
PH (1) PH14723A (xx)
PL (1) PL104376B1 (xx)
PT (1) PT65949B (xx)
RO (1) RO72475A (xx)
SE (1) SE431544B (xx)
SU (1) SU791235A3 (xx)
YU (1) YU311676A (xx)
ZA (1) ZA767198B (xx)
ZM (1) ZM14376A1 (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186511A (en) 1977-03-19 1980-11-14 Smith Kline French Lab 3-substituted alkylamino-6-substituted alkyl-1,2,4-triazin-5-ones and pharmaceutical compositions 3-substituted thio-1,2,4-triazin-5-ones
IL56265A (en) * 1977-12-28 1982-08-31 Om Lab Sa Process for preparing imidazolyl methylthio guanidine derivatives and a novel intermediate therefor
IN151188B (xx) * 1978-02-13 1983-03-05 Smith Kline French Lab
US4539207A (en) * 1978-02-13 1985-09-03 Smith Kline & French Laboratories Limited Pyrimidine compounds
AU527202B2 (en) * 1978-04-11 1983-02-24 Smith Kline & French Laboratories Limited 2-aminopyrimidones
ZA792607B (en) * 1978-05-30 1980-07-30 Smith Kline French Lab Nitro compounds
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas
US4309435A (en) 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
US4374836A (en) 1978-10-16 1983-02-22 Imperial Chemical Industries Ltd. Antisecretory heterocyclic derivatives, process for their manufacture and pharmaceutical compositions containing them
US4496567A (en) * 1978-11-13 1985-01-29 Smith Kline & French Laboratories Limited Phenyl alkylaminopyrimidones
US4521418A (en) * 1979-02-21 1985-06-04 Smith Kline & French Laboratories Limited Guanidinothiazolyl derivatives
US4255428A (en) 1979-03-24 1981-03-10 Smith Kline & French Laboratories Limited 5-(Hydroxypyridylalkyl)-4-pyrimidones
JPS55133379A (en) * 1979-04-05 1980-10-17 Smith Kline French Lab Pyrimidone compound
DE2962542D1 (en) * 1979-04-11 1982-06-03 Smith Kline French Lab Pyrimidone derivatives, process for preparing them and pharmaceutical compositions containing them
JPS55145683A (en) * 1979-04-26 1980-11-13 Smith Kline French Lab Pyrimidone derivative
CA1155842A (en) * 1980-03-29 1983-10-25 Thomas H. Brown Compounds
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
IE53068B1 (en) * 1981-06-15 1988-05-25 Merck & Co Inc Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors
PT75074B (en) * 1981-06-27 1986-02-26 Smith Kline French Lab Process for preparing certain pyrimidone derivatives and compositions containing them
US6417366B2 (en) * 1999-06-24 2002-07-09 Abbott Laboratories Preparation of quinoline-substituted carbonate and carbamate derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
IN146736B (xx) * 1975-10-02 1979-08-25 Smith Kline French Lab

Also Published As

Publication number Publication date
DK587076A (da) 1977-06-30
PH14723A (en) 1981-11-13
SE431544B (sv) 1984-02-13
NL7614538A (nl) 1977-07-01
DD128588A5 (de) 1977-11-30
CH631981A5 (en) 1982-09-15
NO764370L (xx) 1977-06-30
RO72475A (ro) 1982-10-26
DE2658267A1 (de) 1977-07-07
ZA767198B (en) 1977-11-30
NO146396C (no) 1982-09-22
EG12439A (en) 1979-09-30
ES454656A1 (es) 1977-11-16
NZ182759A (en) 1978-06-02
SE7614620L (sv) 1977-06-30
CS203995B2 (en) 1981-03-31
AT360024B (de) 1980-12-10
AU2097676A (en) 1978-07-06
OA05526A (fr) 1981-04-30
PT65949A (pt) 1977-01-01
ATA960876A (de) 1980-05-15
HU175171B (hu) 1980-05-28
IL51040A0 (en) 1977-02-28
BE849810A (fr) 1977-06-23
GR62441B (en) 1979-04-12
IT1124740B (it) 1986-05-14
PT65949B (pt) 1978-06-15
YU311676A (en) 1983-01-21
BG29722A3 (en) 1981-01-15
IE45082L (en) 1977-06-29
ZM14376A1 (en) 1977-08-22
IE45082B1 (en) 1982-06-16
CA1073458A (en) 1980-03-11
JPS5283388A (en) 1977-07-12
FR2336935A1 (fr) 1977-07-29
JPS6129355B2 (xx) 1986-07-05
FI62668C (fi) 1983-02-10
FR2336935B1 (xx) 1980-03-21
IT7919107A0 (it) 1979-01-05
LU76481A1 (xx) 1977-06-15
FI763664A (xx) 1977-06-30
AR222290A1 (es) 1981-05-15
SU791235A3 (ru) 1980-12-23
NO146396B (no) 1982-06-14
FI62668B (fi) 1982-10-29
PL104376B1 (pl) 1979-08-31
MX5119E (es) 1983-03-24
AU508123B2 (en) 1980-03-13
MW5076A1 (en) 1978-02-08

Similar Documents

Publication Publication Date Title
DE2860900D1 (en) Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
HU179401B (en) Process for preparing tetracuclic benzo-pyrazino/imidazo,diazepino/-pyrido-azepine derivatives further pharmaceutical compositions containing thereof
GB1518444A (en) N-phenyl-imidazolidine derivatives processes for preparing them and pharmaceutical compositions containing them
IL51040A (en) 2-heteroarylmethylthioethylamino-5-heteroarylalkylpyrimidin-4-one derivatives,process for their preparation und pharmaceutical compositions containing them
IL49022A0 (en) Isoxazolylbenzamide derivatives,their production and pharmaceutical compositions containing them
IL49911A0 (en) New 5-aroylpyrrole derivatives,their preparation and pharmaceutical compositions containing them
IL49411A0 (en) Phenylalkane-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL45123A0 (en) 5-methyl-isoflavone-derivatives,process for preparation thereof and pharmaceutical compositions containing them
IL48806A0 (en) New biphenyloxy derivatives,their preparation and pharmaceutical compositions containing them
IL50869A (en) Heterocyclylthio-ethylimidazole derivatives,their preparation and pharmaceutical compositions containing them
DE2861361D1 (en) 1-n-acylated-4-o-glycosyl-6-o-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them
IL50736A0 (en) Phenoxyalkylcarboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
DE2861482D1 (en) Pyrazino-benzoxazepine and -benzthiazepine derivatives, processes for their production and pharmaceutical compositions containing them
IL49758A0 (en) Novel phenothiazine derivatives,their preparation and pharmaceutical compositions containing them
IL50897A (en) Daunorubicin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL50335A (en) Diphenylalkylpolyamine derivatives,their preparation and pharmaceutical compositions containing them
IL50156A0 (en) New homophthalimide derivatives,their preparation and pharmaceutical compositions containing them
DE2861767D1 (en) Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them
GB1552460A (en) Diphenylacetamide derivatives processes for their preparation and pharmaceutical compositions containing them
IL49862A0 (en) New benzocycloheptathiophene derivatives,their production and pharmaceutical compositions containing them
IL49971A0 (en) New 2-benzoypranone derivatives,their preparation and pharmaceutical compositions containing them
IL50399A (en) Substituted sulphoximides,a process for their preparation and pharmaceutical compositions containing these compounds
IL49785A0 (en) Benzocycloheptathiophene derivatives,their production and pharmaceutical compositions containing them
GB1522212A (en) Glutamine derivatives process for their preparation and pharmaceutical compositions containing them
IL52207A (en) Substituted 2-vinyl-chromones, process for their preparation and pharmaceutical compositions containing them