NO138628C - Analogifremgangsmaate for fremstilling av farmakodynamisk aktive, basisk substituerte indanderivater - Google Patents

Analogifremgangsmaate for fremstilling av farmakodynamisk aktive, basisk substituerte indanderivater

Info

Publication number
NO138628C
NO138628C NO1209/73A NO120973A NO138628C NO 138628 C NO138628 C NO 138628C NO 1209/73 A NO1209/73 A NO 1209/73A NO 120973 A NO120973 A NO 120973A NO 138628 C NO138628 C NO 138628C
Authority
NO
Norway
Prior art keywords
indian
derivatives
preparation
basic substituted
analogical procedure
Prior art date
Application number
NO1209/73A
Other languages
English (en)
Norwegian (no)
Other versions
NO138628B (no
Inventor
Barbro Ka Goeransson-Dahlander
Nils Aake Joensson
Ferenc Merenyi
Original Assignee
Kabi Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Ab filed Critical Kabi Ab
Publication of NO138628B publication Critical patent/NO138628B/no
Publication of NO138628C publication Critical patent/NO138628C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/665Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system
    • C07C49/675Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings a keto group being part of a condensed ring system having three rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/687Unsaturated compounds containing a keto groups being part of a ring containing halogen
    • C07C49/697Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
NO1209/73A 1972-03-24 1973-03-23 Analogifremgangsmaate for fremstilling av farmakodynamisk aktive, basisk substituerte indanderivater NO138628C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7203905A SE371190B (fi) 1972-03-24 1972-03-24

Publications (2)

Publication Number Publication Date
NO138628B NO138628B (no) 1978-07-03
NO138628C true NO138628C (no) 1978-10-11

Family

ID=20263107

Family Applications (1)

Application Number Title Priority Date Filing Date
NO1209/73A NO138628C (no) 1972-03-24 1973-03-23 Analogifremgangsmaate for fremstilling av farmakodynamisk aktive, basisk substituerte indanderivater

Country Status (12)

Country Link
US (1) US4172093A (fi)
JP (1) JPS599540B2 (fi)
AT (1) AT329045B (fi)
CA (1) CA1032165A (fi)
CH (4) CH621110A5 (fi)
DE (1) DE2314636C2 (fi)
DK (1) DK138598B (fi)
FI (1) FI57253C (fi)
FR (1) FR2177929B1 (fi)
GB (1) GB1421208A (fi)
NO (1) NO138628C (fi)
SE (1) SE371190B (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE47716B1 (en) * 1977-08-05 1984-05-30 Kabi Ab Geminally disubstituted indene derivatives
CH641147A5 (de) * 1979-01-17 1984-02-15 Sandoz Ag 3-amino-2-hydroxypropoxyaryl-derivat, seine herstellung und dieses enthaltende heilmittel.
CH647235A5 (de) * 1980-02-13 1985-01-15 Sandoz Ag 4-(2,2-dialkylindan-1-yliden)piperidin derivate, ihre herstellung und verwendung.
IL103106A (en) * 1991-09-25 1998-06-15 Sanofi Elf Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them
GB9309621D0 (en) * 1993-05-11 1993-06-23 Wellcome Found Amide derivatives and their therapeutic use
US5877218A (en) * 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
MY113062A (en) * 1994-05-10 2001-11-30 The Wellcome Foundation Ltd Amide derivatives and their therapeutic use
EP0966435B1 (en) 1996-12-18 2005-04-06 Teva Pharmaceutical Industries, Ltd. Aminoindan derivatives
US6124284A (en) * 1998-07-16 2000-09-26 Glaxo Wellcome Inc. Bicyclic amide derivatives and their use as muscle relaxants
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
GB0328906D0 (en) 2003-12-12 2004-01-14 Syngenta Participations Ag Chemical compounds
ES2632638T3 (es) * 2005-12-09 2017-09-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Ladostigilo de baja dosis para el tratamiento de la deficiencia cognitiva
US20070135518A1 (en) * 2005-12-09 2007-06-14 Marta Weinstock-Rosin Use of low-dose ladostigil for neuroprotection
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1007323B (de) * 1956-04-13 1957-05-02 Schering Ag Verfahren zur Herstellung von 1-Aminoindanen mit coronargefaesserweiternder Wirkung
US3308157A (en) * 1964-08-07 1967-03-07 Colgate Palmolive Co N-(benzocyclobutene-1-loweralkyl)-carboxylic acid amides
US3360435A (en) * 1964-09-15 1967-12-26 Mead Johnson & Co Treatment of depressed states
US3553093A (en) * 1965-03-19 1971-01-05 Xerox Corp Color photoelectrophoretic imaging process
GB1139135A (en) * 1965-10-01 1969-01-08 Kefalas As Aminoalkyl-substituted indanes and pharmaceutical compositions containing them
US3657440A (en) * 1968-04-23 1972-04-18 Ciba Geigy Corp Aminoalkyl-spirocycloalkanes as analgetic agents
CH554310A (de) * 1968-04-23 1974-09-30 Ciba Geigy Ag Verfahren zur herstellung von neuen 1-aminoalkylidenbenzcycloalkan-2-spirocycloaliphatischen verbindungen.

Also Published As

Publication number Publication date
DE2314636C2 (de) 1986-09-11
CH626044A5 (fi) 1981-10-30
DK138598C (fi) 1979-03-26
FI57253C (fi) 1980-07-10
CA1032165A (en) 1978-05-30
CH621110A5 (fi) 1981-01-15
DK138598B (da) 1978-10-02
FI57253B (fi) 1980-03-31
ATA255373A (de) 1975-07-15
JPS495957A (fi) 1974-01-19
SE371190B (fi) 1974-11-11
DE2314636A1 (de) 1973-10-04
NO138628B (no) 1978-07-03
FR2177929B1 (fi) 1976-10-22
CH626045A5 (fi) 1981-10-30
GB1421208A (en) 1976-01-14
CH622769A5 (fi) 1981-04-30
AU5365173A (en) 1974-09-26
US4172093A (en) 1979-10-23
AT329045B (de) 1976-04-26
FR2177929A1 (fi) 1973-11-09
JPS599540B2 (ja) 1984-03-03

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