NO137897C - Fremgangsmaate til fremstilling av optisk aktive 1,4-benzdiazepin-2-on-derivater - Google Patents

Fremgangsmaate til fremstilling av optisk aktive 1,4-benzdiazepin-2-on-derivater

Info

Publication number
NO137897C
NO137897C NO742739A NO742739A NO137897C NO 137897 C NO137897 C NO 137897C NO 742739 A NO742739 A NO 742739A NO 742739 A NO742739 A NO 742739A NO 137897 C NO137897 C NO 137897C
Authority
NO
Norway
Prior art keywords
benzdiazepin
derivatives
procedure
optically active
preparing optically
Prior art date
Application number
NO742739A
Other languages
English (en)
Norwegian (no)
Other versions
NO742739L (he
NO137897B (no
Inventor
Franjo Kajfez
Vitomir Sunjic
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of NO742739L publication Critical patent/NO742739L/no
Publication of NO137897B publication Critical patent/NO137897B/no
Publication of NO137897C publication Critical patent/NO137897C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO742739A 1973-07-30 1974-07-29 Fremgangsmaate til fremstilling av optisk aktive 1,4-benzdiazepin-2-on-derivater NO137897C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1105673A CH573928A5 (he) 1973-07-30 1973-07-30

Publications (3)

Publication Number Publication Date
NO742739L NO742739L (he) 1975-02-24
NO137897B NO137897B (no) 1978-02-06
NO137897C true NO137897C (no) 1978-05-16

Family

ID=4369623

Family Applications (1)

Application Number Title Priority Date Filing Date
NO742739A NO137897C (no) 1973-07-30 1974-07-29 Fremgangsmaate til fremstilling av optisk aktive 1,4-benzdiazepin-2-on-derivater

Country Status (21)

Country Link
US (1) US4010153A (he)
JP (1) JPS5041886A (he)
AR (1) AR202224A1 (he)
AT (1) AT337192B (he)
BE (1) BE818047A (he)
CA (1) CA1021778A (he)
CH (1) CH573928A5 (he)
DE (1) DE2436744A1 (he)
DK (1) DK138798B (he)
ES (1) ES428675A1 (he)
FI (1) FI227474A (he)
FR (1) FR2239464B1 (he)
GB (1) GB1481219A (he)
HU (1) HU169180B (he)
IE (1) IE39904B1 (he)
IL (1) IL45289A (he)
NL (1) NL7410256A (he)
NO (1) NO137897C (he)
SE (2) SE7409708L (he)
SU (1) SU528872A3 (he)
ZA (1) ZA744635B (he)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
HUE060259T2 (hu) 2015-07-22 2023-02-28 Enanta Pharm Inc Benzodiazepin származékok mint RSV-gátlók
CN108699077B (zh) 2016-01-15 2021-03-02 英安塔制药有限公司 作为rsv抑制剂的杂环化合物
CA3065368A1 (en) 2017-02-16 2018-08-23 Enanta Pharmaceuticals, Inc. Processes for the preparation of benzodiazepine derivatives
US10752598B2 (en) 2017-06-07 2020-08-25 Enanta Pharmaceuticals, Inc. Aryldiazepine derivatives as RSV inhibitors
US11091501B2 (en) 2017-06-30 2021-08-17 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
US10851115B2 (en) 2017-06-30 2020-12-01 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
BR112020006334A2 (pt) 2017-09-29 2020-09-24 Enanta Pharmaceuticals, Inc. combinação de agentes farmacêuticos como inibidores de rsv
WO2019094903A1 (en) * 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
WO2019094920A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Azepin-2-one derivatives as rsv inhibitors
US10975094B2 (en) 2018-04-11 2021-04-13 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
KR20210138684A (ko) 2019-03-18 2021-11-19 이난타 파마슈티칼스, 인코포레이티드 Rsv 억제제로서의 벤조디아제핀 유도체
US11179400B2 (en) 2019-04-09 2021-11-23 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
WO2022086840A1 (en) 2020-10-19 2022-04-28 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
JPS4426302Y1 (he) * 1966-04-22 1969-11-05

Also Published As

Publication number Publication date
NL7410256A (nl) 1975-02-03
FR2239464A1 (he) 1975-02-28
IE39904B1 (en) 1979-01-31
FI227474A (he) 1975-01-31
DK393274A (he) 1975-04-01
SE7409708L (he) 1975-01-31
ATA567674A (de) 1976-10-15
GB1481219A (en) 1977-07-27
FR2239464B1 (he) 1978-04-14
BE818047A (fr) 1974-11-18
NO742739L (he) 1975-02-24
CA1021778A (en) 1977-11-29
DK138798B (da) 1978-10-30
US4010153A (en) 1977-03-01
ES428675A1 (es) 1976-09-01
SE7510823L (sv) 1975-09-26
DE2436744A1 (de) 1975-02-27
IL45289A0 (en) 1974-10-22
HU169180B (he) 1976-10-28
ZA744635B (en) 1975-08-27
IE39904L (en) 1975-01-30
AT337192B (de) 1977-06-10
CH573928A5 (he) 1976-03-31
IL45289A (en) 1979-12-30
SU528872A3 (ru) 1976-09-15
NO137897B (no) 1978-02-06
DK138798C (he) 1979-04-09
JPS5041886A (he) 1975-04-16
AR202224A1 (es) 1975-05-23

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