NL7410256A - Werkwijze voor de bereiding van chirale (optisch aktieve) 1,4-benzodiazepin-2-on-deriva- - Google Patents

Werkwijze voor de bereiding van chirale (optisch aktieve) 1,4-benzodiazepin-2-on-deriva-

Info

Publication number
NL7410256A
NL7410256A NL7410256A NL7410256A NL7410256A NL 7410256 A NL7410256 A NL 7410256A NL 7410256 A NL7410256 A NL 7410256A NL 7410256 A NL7410256 A NL 7410256A NL 7410256 A NL7410256 A NL 7410256A
Authority
NL
Netherlands
Prior art keywords
deriva
benzodiazepin
chiral
preparation
optically active
Prior art date
Application number
NL7410256A
Other languages
English (en)
Dutch (nl)
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of NL7410256A publication Critical patent/NL7410256A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NL7410256A 1973-07-30 1974-07-30 Werkwijze voor de bereiding van chirale (optisch aktieve) 1,4-benzodiazepin-2-on-deriva- NL7410256A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1105673A CH573928A5 (xx) 1973-07-30 1973-07-30

Publications (1)

Publication Number Publication Date
NL7410256A true NL7410256A (nl) 1975-02-03

Family

ID=4369623

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7410256A NL7410256A (nl) 1973-07-30 1974-07-30 Werkwijze voor de bereiding van chirale (optisch aktieve) 1,4-benzodiazepin-2-on-deriva-

Country Status (21)

Country Link
US (1) US4010153A (xx)
JP (1) JPS5041886A (xx)
AR (1) AR202224A1 (xx)
AT (1) AT337192B (xx)
BE (1) BE818047A (xx)
CA (1) CA1021778A (xx)
CH (1) CH573928A5 (xx)
DE (1) DE2436744A1 (xx)
DK (1) DK138798B (xx)
ES (1) ES428675A1 (xx)
FI (1) FI227474A (xx)
FR (1) FR2239464B1 (xx)
GB (1) GB1481219A (xx)
HU (1) HU169180B (xx)
IE (1) IE39904B1 (xx)
IL (1) IL45289A (xx)
NL (1) NL7410256A (xx)
NO (1) NO137897C (xx)
SE (2) SE7409708L (xx)
SU (1) SU528872A3 (xx)
ZA (1) ZA744635B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
PL3324977T3 (pl) 2015-07-22 2022-11-14 Enanta Pharmaceuticals, Inc. Pochodne benzodiazepiny jako inhibitory rsv
US20170226129A1 (en) 2016-01-15 2017-08-10 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
ES2923521T3 (es) 2017-02-16 2022-09-28 Enanta Pharm Inc Procesos para la preparación de derivados de benzodiazepina
US10752598B2 (en) 2017-06-07 2020-08-25 Enanta Pharmaceuticals, Inc. Aryldiazepine derivatives as RSV inhibitors
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
US10851115B2 (en) 2017-06-30 2020-12-01 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
CA3077309A1 (en) 2017-09-29 2019-04-04 Enanta Pharmaceuticals, Inc. Combination pharmaceutical agents as rsv inhibitors
US10647711B2 (en) 2017-11-13 2020-05-12 Enanta Pharmaceuticals, Inc. Azepin-2-one derivatives as RSV inhibitors
AU2018365174B2 (en) * 2017-11-13 2023-03-30 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
US10975094B2 (en) 2018-04-11 2021-04-13 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
US11254664B2 (en) 2019-03-18 2022-02-22 Enanta Pharmaceuticals, Inc. Benzodiazepine derivatives as RSV inhibitors
WO2020210246A1 (en) 2019-04-09 2020-10-15 Enanta Pharmaceuticals, Inc, Heterocyclic compounds as rsv inhibitors
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
US11945824B2 (en) 2020-10-19 2024-04-02 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
JPS4426302Y1 (xx) * 1966-04-22 1969-11-05

Also Published As

Publication number Publication date
SE7510823L (sv) 1975-09-26
JPS5041886A (xx) 1975-04-16
IE39904L (en) 1975-01-30
GB1481219A (en) 1977-07-27
IL45289A0 (en) 1974-10-22
IL45289A (en) 1979-12-30
AT337192B (de) 1977-06-10
DE2436744A1 (de) 1975-02-27
FI227474A (xx) 1975-01-31
ZA744635B (en) 1975-08-27
ES428675A1 (es) 1976-09-01
NO742739L (xx) 1975-02-24
SE7409708L (xx) 1975-01-31
AR202224A1 (es) 1975-05-23
US4010153A (en) 1977-03-01
DK138798C (xx) 1979-04-09
BE818047A (fr) 1974-11-18
FR2239464B1 (xx) 1978-04-14
CH573928A5 (xx) 1976-03-31
DK138798B (da) 1978-10-30
IE39904B1 (en) 1979-01-31
NO137897B (no) 1978-02-06
HU169180B (xx) 1976-10-28
SU528872A3 (ru) 1976-09-15
ATA567674A (de) 1976-10-15
DK393274A (xx) 1975-04-01
CA1021778A (en) 1977-11-29
FR2239464A1 (xx) 1975-02-28
NO137897C (no) 1978-05-16

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Legal Events

Date Code Title Description
BN A decision not to publish the application has become irrevocable