DK138798B - Fremgangsmåde til fremstilling af optisk aktive 1,4-benzodiazepin-2-on-derivater. - Google Patents

Fremgangsmåde til fremstilling af optisk aktive 1,4-benzodiazepin-2-on-derivater.

Info

Publication number
DK138798B
DK138798B DK393274AA DK393274A DK138798B DK 138798 B DK138798 B DK 138798B DK 393274A A DK393274A A DK 393274AA DK 393274 A DK393274 A DK 393274A DK 138798 B DK138798 B DK 138798B
Authority
DK
Denmark
Prior art keywords
benzodiazepin
derivatives
preparation
optically active
optically
Prior art date
Application number
DK393274AA
Other languages
English (en)
Other versions
DK138798C (da
DK393274A (da
Inventor
Franjo Krajfez
Vitomir Sunjic
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of DK393274A publication Critical patent/DK393274A/da
Publication of DK138798B publication Critical patent/DK138798B/da
Application granted granted Critical
Publication of DK138798C publication Critical patent/DK138798C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK393274AA 1973-07-30 1974-07-22 Fremgangsmåde til fremstilling af optisk aktive 1,4-benzodiazepin-2-on-derivater. DK138798B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1105673A CH573928A5 (da) 1973-07-30 1973-07-30

Publications (3)

Publication Number Publication Date
DK393274A DK393274A (da) 1975-04-01
DK138798B true DK138798B (da) 1978-10-30
DK138798C DK138798C (da) 1979-04-09

Family

ID=4369623

Family Applications (1)

Application Number Title Priority Date Filing Date
DK393274AA DK138798B (da) 1973-07-30 1974-07-22 Fremgangsmåde til fremstilling af optisk aktive 1,4-benzodiazepin-2-on-derivater.

Country Status (21)

Country Link
US (1) US4010153A (da)
JP (1) JPS5041886A (da)
AR (1) AR202224A1 (da)
AT (1) AT337192B (da)
BE (1) BE818047A (da)
CA (1) CA1021778A (da)
CH (1) CH573928A5 (da)
DE (1) DE2436744A1 (da)
DK (1) DK138798B (da)
ES (1) ES428675A1 (da)
FI (1) FI227474A (da)
FR (1) FR2239464B1 (da)
GB (1) GB1481219A (da)
HU (1) HU169180B (da)
IE (1) IE39904B1 (da)
IL (1) IL45289A (da)
NL (1) NL7410256A (da)
NO (1) NO137897C (da)
SE (2) SE7409708L (da)
SU (1) SU528872A3 (da)
ZA (1) ZA744635B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
AU2016297024B2 (en) 2015-07-22 2021-03-04 Enanta Pharmaceuticals, Inc. Benzodiazepine derivatives as RSV inhibitors
EP3402799B1 (en) 2016-01-15 2022-05-04 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
EP3582784B1 (en) 2017-02-16 2022-06-08 Enanta Pharmaceuticals, Inc. Processes for the preparation of benzodiazepine derivatives
WO2018226801A1 (en) 2017-06-07 2018-12-13 Enanta Pharmaceuticals, Inc. Aryldiazepine derivatives as rsv inhibitors
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019006291A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
WO2019067864A1 (en) 2017-09-29 2019-04-04 Enanta Pharmaceuticals, Inc. PHARMACEUTICAL AGENTS IN COMBINATION AS INHIBITORS OF RSV
CA3080138A1 (en) * 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
WO2019094920A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Azepin-2-one derivatives as rsv inhibitors
WO2019199908A1 (en) 2018-04-11 2019-10-17 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
MX2021011144A (es) 2019-03-18 2022-01-18 Enanta Pharm Inc Derivados de las benzodiazepinas como inhibidores del vsr.
WO2020210246A1 (en) 2019-04-09 2020-10-15 Enanta Pharmaceuticals, Inc, Heterocyclic compounds as rsv inhibitors
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en) 2020-07-07 2022-12-27 Enanta Pharmaceuticals, Inc. Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
US11945824B2 (en) 2020-10-19 2024-04-02 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
JPS4426302Y1 (da) * 1966-04-22 1969-11-05

Also Published As

Publication number Publication date
IL45289A (en) 1979-12-30
NO137897B (no) 1978-02-06
DK138798C (da) 1979-04-09
FI227474A (da) 1975-01-31
NO742739L (da) 1975-02-24
SU528872A3 (ru) 1976-09-15
ES428675A1 (es) 1976-09-01
CH573928A5 (da) 1976-03-31
HU169180B (da) 1976-10-28
SE7409708L (da) 1975-01-31
BE818047A (fr) 1974-11-18
ZA744635B (en) 1975-08-27
IE39904B1 (en) 1979-01-31
US4010153A (en) 1977-03-01
IE39904L (en) 1975-01-30
DE2436744A1 (de) 1975-02-27
CA1021778A (en) 1977-11-29
AT337192B (de) 1977-06-10
ATA567674A (de) 1976-10-15
FR2239464B1 (da) 1978-04-14
NL7410256A (nl) 1975-02-03
IL45289A0 (en) 1974-10-22
FR2239464A1 (da) 1975-02-28
DK393274A (da) 1975-04-01
NO137897C (no) 1978-05-16
GB1481219A (en) 1977-07-27
AR202224A1 (es) 1975-05-23
JPS5041886A (da) 1975-04-16
SE7510823L (sv) 1975-09-26

Similar Documents

Publication Publication Date Title
DK139099B (da) Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5.
DK134345B (da) Analogifremgangsmåde til fremstilling af 4-hydroxymethyl-1-phthalazonderivater.
DK138798B (da) Fremgangsmåde til fremstilling af optisk aktive 1,4-benzodiazepin-2-on-derivater.
DK134490B (da) Analogifremgangsmåde til fremstilling af 2,6-diaminonebularin-derivater.
DK139678B (da) Fremgangsmåde til fremstilling af 2,2,6,6-tetramethyl-4-oxopiperidin.
DK140406B (da) Fremgangsmåde til fremstilling af 2,2,6,6-tetramethyl-4-oxopiperidin.
DK138759B (da) Fremgangsmåde til fremstilling af D-ribose.
DK137389B (da) Analogifremgangsmåde til fremstilling af 11beta-substituerede delta4-østrener.
DK135723B (da) Analogifremgangsmåde til fremstilling af 7alfa-acylthio-3-oxo-D-homo-21,24-dinor-17aalfa-chlo-4-en-23,17a-lactoner.
DK132328B (da) Analogifremgangsmåde til fremstilling af 17beta-hydroxy-16,16-dimethylestr-4-en-3-on.
DK139716B (da) Analogifremgangsmåde til fremstilling af 4-aminoamfetaminderivater.
DK135167B (da) Analogifremgangsmåde til fremstilling af 7,7'-ditheophyllinderivater.
DK132329B (da) Fremgangsmåde til fremstilling af cardenolid-3,alfa-/2'-desoxy-glycosider/.
DK131855B (da) Fremgangsmåde til fremstilling af 3,4-dihydropyridoner.
DK127421B (da) Fremgangsmåde til fremstilling af cardenolid-3[2',3'-didesoxyglycosider].
DK138895B (da) Fremgangsmåde til fremstilling af 8-beta-(2'-pyrimidino-aminometyl)-ergolinderivater.
DK137754B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK136619B (da) Fremgangsmåde til fremstilling af dihydrokanadensolid.
DK137924B (da) Fremgangsmaade til fremstilling af 1,4-dihydroquinoliner
DK137928B (da) Fremgangsmåde til fremstilling af 5alfa-hydroxygona-9,11-diener.
DK136776B (da) Analogifremgangsmåde til fremstilling af 17aalfa-alkanoyloxy-D-homopregn-4-en-3,20-dioner.
DK135133B (da) Fremgangsmåde til fremstilling af 21-fluor-16alfa,17alfa-alkylidendioxy-20-oxo-steroider.
DK135809B (da) Analogifremgangsmåde til fremstilling af 4-oxo-benzocycloheptathiophenderivater.
DK127115B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK138314B (da) Fremgangsmåde til fremstilling af racemisk 13beta-ætyl-3-metoxy-8,14-seco-gona-1,3,5(10),8-tetraen-17beta-ol-14-on.