DK139099B - Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5. - Google Patents

Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5.

Info

Publication number
DK139099B
DK139099B DK125874AA DK125874A DK139099B DK 139099 B DK139099 B DK 139099B DK 125874A A DK125874A A DK 125874AA DK 125874 A DK125874 A DK 125874A DK 139099 B DK139099 B DK 139099B
Authority
DK
Denmark
Prior art keywords
benzodiazepines
triazolo
dihydro
preparation
analogous process
Prior art date
Application number
DK125874AA
Other languages
English (en)
Other versions
DK139099C (da
Inventor
Etienne Szarvasi
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7308510A external-priority patent/FR2220257A1/fr
Priority claimed from FR7335522A external-priority patent/FR2246273A2/fr
Priority claimed from FR7341583A external-priority patent/FR2252102A2/fr
Application filed by Lipha filed Critical Lipha
Publication of DK139099B publication Critical patent/DK139099B/da
Application granted granted Critical
Publication of DK139099C publication Critical patent/DK139099C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK125874AA 1973-03-09 1974-03-08 Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5. DK139099B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7308510A FR2220257A1 (en) 1973-03-09 1973-03-09 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects
FR7335522A FR2246273A2 (en) 1973-10-04 1973-10-04 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects
FR7341583A FR2252102A2 (en) 1973-11-22 1973-11-22 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects

Publications (2)

Publication Number Publication Date
DK139099B true DK139099B (da) 1978-12-18
DK139099C DK139099C (da) 1979-05-28

Family

ID=27250074

Family Applications (1)

Application Number Title Priority Date Filing Date
DK125874AA DK139099B (da) 1973-03-09 1974-03-08 Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5.

Country Status (13)

Country Link
US (1) US4110337A (da)
JP (1) JPS49125395A (da)
CA (1) CA1011333A (da)
CH (1) CH589084A5 (da)
DD (1) DD110497A5 (da)
DE (1) DE2409308C3 (da)
DK (1) DK139099B (da)
ES (1) ES424067A1 (da)
GB (1) GB1409693A (da)
IE (1) IE38931B1 (da)
IL (1) IL44338A (da)
NL (1) NL7403247A (da)
NO (1) NO139048C (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076823A (en) * 1977-08-18 1978-02-28 E. R. Squibb & Sons, Inc. Triazolo-2,4-benzodiazepines
US5683998A (en) * 1991-04-23 1997-11-04 Toray Industries, Inc. Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
AU654548B2 (en) * 1991-04-23 1994-11-10 Toray Industries, Inc. Tricyclic triazole derivative, production thereof, and use thereof
FR2769309B1 (fr) 1997-10-08 2001-06-15 Oreal Composition de teinture d'oxydation des fibres keratiniques comprenant un derive d'aminoacide en tant que base d'oxydation et nouveaux derives d'aminoacides
US7276348B2 (en) * 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US7144880B2 (en) * 1999-04-30 2006-12-05 Regents Of The University Of Michigan Compositions relating to novel compounds and targets thereof
US20060025388A1 (en) * 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US20040176358A1 (en) * 1999-04-30 2004-09-09 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
IL146222A0 (en) 1999-04-30 2002-07-25 Univ Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US20030119029A1 (en) * 1999-04-30 2003-06-26 Regents Of The University Of Michigan Compositions and methods relating to novel benzodiazepine compounds and targets thereof
US20050113460A1 (en) * 1999-04-30 2005-05-26 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US20050272723A1 (en) * 2004-04-27 2005-12-08 The Regents Of The University Of Michigan Methods and compositions for treating diseases and conditions associated with mitochondrial function
US20060052369A1 (en) * 2004-09-07 2006-03-09 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7638624B2 (en) * 2005-01-03 2009-12-29 The Regents Of The University Of Michigan Compositions and methods relating to novel benzodiazepine compounds and derivatives
EP1893218A4 (en) * 2005-06-01 2011-01-12 Univ Michigan UNLOCKED BENZODIAZEPINE COMPOSITIONS AND METHOD
US20070105844A1 (en) * 2005-10-26 2007-05-10 Regents Of The University Of Michigan Therapeutic compositions and methods
CA2628193C (en) 2005-11-01 2012-08-14 The Regents Of The University Of Michigan Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties
DE102005061840A1 (de) * 2005-12-23 2007-06-28 Merck Patent Gmbh Triazolderivate
US7759338B2 (en) * 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
EP2037741B1 (en) 2006-06-09 2013-11-27 The Regents Of The University Of Michigan Benzodiazepine derivatives for use in the treatment of immune, inflammatory and proliferative disorders
CN101662940A (zh) 2007-03-09 2010-03-03 密执安州立大学董事会 与新化合物及其靶标有关的组合物和方法
JP5416122B2 (ja) 2007-09-14 2014-02-12 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン Ｆ１Ｆ０−ＡＴＰａｓｅインヒビターおよび関連の方法
RU2010122902A (ru) 2007-11-06 2011-12-20 Дзе Риджентс оф дзе Юниверсити оф Мичиган (US) Бензодиапениноновые соединения, применимые в лечении кожных состояний
JP5567573B2 (ja) 2008-09-11 2014-08-06 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン アリールグアニジンｆ１ｆ０−ａｔｐアーゼ阻害剤およびそれと関連する方法
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
US8673897B2 (en) 2009-09-18 2014-03-18 The Regents Of The University Of Michigan Benzodiazepinone compounds and methods of treatment using same
CN102753179A (zh) 2009-11-17 2012-10-24 密执安大学评议会 具有治疗性能的1,4-苯并二氮杂*-2,5-二酮和相关化合物
AU2010322287B2 (en) 2009-11-17 2014-04-03 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
WO2012151512A2 (en) * 2011-05-04 2012-11-08 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9328117B2 (en) 2011-06-17 2016-05-03 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9624244B2 (en) 2012-06-06 2017-04-18 Constellation Pharmaceuticals, Inc. Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
CN106687463B (zh) 2014-06-20 2019-04-09 星座制药公司 一种乙酰胺类化合物的晶型

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681343A (en) * 1971-05-11 1972-08-01 Upjohn Co 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines

Also Published As

Publication number Publication date
DE2409308C3 (de) 1978-05-18
IL44338A (en) 1977-01-31
DE2409308A1 (de) 1974-09-19
DD110497A5 (da) 1974-12-20
AU6627674A (en) 1975-09-11
IE38931L (en) 1974-09-09
IE38931B1 (en) 1978-07-05
NO139048B (no) 1978-09-18
CA1011333A (en) 1977-05-31
DK139099C (da) 1979-05-28
NO139048C (no) 1979-01-03
CH589084A5 (da) 1977-06-30
US4110337A (en) 1978-08-29
JPS49125395A (da) 1974-11-30
GB1409693A (en) 1975-10-15
ES424067A1 (es) 1976-06-01
IL44338A0 (en) 1974-06-30
NL7403247A (da) 1974-09-11
DE2409308B2 (de) 1977-09-22
NO740833L (no) 1974-09-10

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