NO129350B - - Google Patents
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- Publication number
- NO129350B NO129350B NO389170A NO389170A NO129350B NO 129350 B NO129350 B NO 129350B NO 389170 A NO389170 A NO 389170A NO 389170 A NO389170 A NO 389170A NO 129350 B NO129350 B NO 129350B
- Authority
- NO
- Norway
- Prior art keywords
- general formula
- thiepine
- dihydrodibenzo
- piperazino
- amidoximes
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 claims description 5
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 238000006386 neutralization reaction Methods 0.000 claims description 4
- 150000007522 mineralic acids Chemical class 0.000 claims description 2
- 150000002825 nitriles Chemical class 0.000 claims description 2
- 150000007524 organic acids Chemical class 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 9
- 150000001875 compounds Chemical class 0.000 description 8
- 241000699670 Mus sp. Species 0.000 description 3
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 3
- -1 8-chloro-10-[4-(3-amino-3-oximinopropyl)-piperazino]-10,11-dihydrodibenzo-[b,f]-thiepine Chemical compound 0.000 description 2
- 208000009132 Catalepsy Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 206010047853 Waxy flexibility Diseases 0.000 description 2
- ZPEIMTDSQAKGNT-UHFFFAOYSA-N chlorpromazine Chemical compound C1=C(Cl)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 0.000 description 2
- 229960001076 chlorpromazine Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- YITAORWEHMMACD-UHFFFAOYSA-N 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine Chemical compound C12=CC(Cl)=CC=C2SC2=CC=CC=C2CC1N1CCNCC1 YITAORWEHMMACD-UHFFFAOYSA-N 0.000 description 1
- LWBLYEUAPNUGIP-UHFFFAOYSA-N 1-(5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine Chemical class C1CNCCN1C1C2=CC=CC=C2SC2=CC=CC=C2C1 LWBLYEUAPNUGIP-UHFFFAOYSA-N 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 150000007514 bases Chemical class 0.000 description 1
- 230000002903 catalepsic effect Effects 0.000 description 1
- 239000003874 central nervous system depressant Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 125000001309 chloro group Chemical group Cl* 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 230000000506 psychotropic effect Effects 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS711069 | 1969-10-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO129350B true NO129350B (ja) | 1974-04-01 |
Family
ID=5419619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO389170A NO129350B (ja) | 1969-10-25 | 1970-10-15 |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS4843915B1 (ja) |
| AT (1) | AT297712B (ja) |
| BE (1) | BE757926A (ja) |
| CH (1) | CH536856A (ja) |
| DE (1) | DE2051950A1 (ja) |
| ES (1) | ES384867A1 (ja) |
| FR (1) | FR2070164B1 (ja) |
| GB (1) | GB1271588A (ja) |
| NL (1) | NL7015529A (ja) |
| NO (1) | NO129350B (ja) |
| SE (1) | SE366746B (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6135595U (ja) * | 1984-08-07 | 1986-03-05 | オムロン株式会社 | 直流型正逆転モ−タの駆動回路 |
| CS249455B1 (en) * | 1985-01-24 | 1987-03-12 | Miroslav Protiva | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation |
| DE102006024007A1 (de) | 2006-05-23 | 2007-11-29 | Abb Technology Ag | Schaltgerät für eine elektrische Schaltanlage zur Energieverteilung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1695798A1 (de) * | 1966-11-29 | 1972-03-02 | Spofa Vereinigte Pharma Werke | Neue Ester der 10-Piperazino-10,11-dihydrodibenzo(b,f)-thiepin-Reihe und Verfahren zur Herstellung derselben |
-
0
- BE BE757926D patent/BE757926A/xx unknown
-
1970
- 1970-10-15 NO NO389170A patent/NO129350B/no unknown
- 1970-10-21 CH CH1554470A patent/CH536856A/de not_active IP Right Cessation
- 1970-10-22 DE DE19702051950 patent/DE2051950A1/de active Pending
- 1970-10-23 NL NL7015529A patent/NL7015529A/xx unknown
- 1970-10-23 SE SE1434370A patent/SE366746B/xx unknown
- 1970-10-23 JP JP9339770A patent/JPS4843915B1/ja active Pending
- 1970-10-23 GB GB5038370A patent/GB1271588A/en not_active Expired
- 1970-10-23 AT AT959170A patent/AT297712B/de not_active IP Right Cessation
- 1970-10-24 ES ES384867A patent/ES384867A1/es not_active Expired
- 1970-10-26 FR FR7038625A patent/FR2070164B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1271588A (en) | 1972-04-19 |
| FR2070164A1 (ja) | 1971-09-10 |
| JPS4843915B1 (ja) | 1973-12-21 |
| FR2070164B1 (ja) | 1974-10-11 |
| NL7015529A (ja) | 1971-04-27 |
| SE366746B (ja) | 1974-05-06 |
| CH536856A (de) | 1973-05-15 |
| AT297712B (de) | 1972-04-10 |
| ES384867A1 (es) | 1973-07-16 |
| BE757926A (fr) | 1971-04-01 |
| DE2051950A1 (de) | 1971-05-06 |
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