NO118495B - - Google Patents
Download PDFInfo
- Publication number
- NO118495B NO118495B NO171205A NO17120567A NO118495B NO 118495 B NO118495 B NO 118495B NO 171205 A NO171205 A NO 171205A NO 17120567 A NO17120567 A NO 17120567A NO 118495 B NO118495 B NO 118495B
- Authority
- NO
- Norway
- Prior art keywords
- group
- atom
- acid residue
- phenthiazine
- solution
- Prior art date
Links
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical class C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 claims description 17
- -1 aliphatic ketones Chemical class 0.000 claims description 11
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 9
- 239000002253 acid Substances 0.000 claims description 8
- 125000004429 atom Chemical group 0.000 claims description 8
- 229910052757 nitrogen Inorganic materials 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 125000000623 heterocyclic group Chemical group 0.000 claims description 5
- 239000002904 solvent Substances 0.000 claims description 5
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 125000005843 halogen group Chemical group 0.000 claims description 4
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 2
- 150000001298 alcohols Chemical class 0.000 claims description 2
- 125000003545 alkoxy group Chemical group 0.000 claims description 2
- 125000002947 alkylene group Chemical group 0.000 claims description 2
- 150000001412 amines Chemical class 0.000 claims description 2
- 150000002170 ethers Chemical class 0.000 claims description 2
- 229910052739 hydrogen Inorganic materials 0.000 claims description 2
- 239000001257 hydrogen Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 229910052717 sulfur Inorganic materials 0.000 claims description 2
- 125000004434 sulfur atom Chemical group 0.000 claims description 2
- 125000001931 aliphatic group Chemical group 0.000 claims 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 23
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 17
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 14
- ROXZSHRRSBRWIW-UHFFFAOYSA-N 1-chloro-n,n-diethylethanamine Chemical compound CCN(CC)C(C)Cl ROXZSHRRSBRWIW-UHFFFAOYSA-N 0.000 description 12
- 239000000047 product Substances 0.000 description 12
- 238000010992 reflux Methods 0.000 description 12
- 239000002244 precipitate Substances 0.000 description 11
- 238000000354 decomposition reaction Methods 0.000 description 8
- IQDGSYLLQPDQDV-UHFFFAOYSA-N dimethylazanium;chloride Chemical compound Cl.CNC IQDGSYLLQPDQDV-UHFFFAOYSA-N 0.000 description 8
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 8
- 238000003776 cleavage reaction Methods 0.000 description 7
- 230000007017 scission Effects 0.000 description 7
- 239000007787 solid Substances 0.000 description 6
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 4
- 229910052753 mercury Inorganic materials 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 description 3
- 239000013078 crystal Substances 0.000 description 3
- 230000002005 ganglioplegic effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 description 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 2
- YSXUYJCXEYNFSM-UHFFFAOYSA-N chloroethane;piperidine Chemical compound CCCl.C1CCNCC1 YSXUYJCXEYNFSM-UHFFFAOYSA-N 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- PSLIMVZEAPALCD-UHFFFAOYSA-N ethanol;ethoxyethane Chemical compound CCO.CCOCC PSLIMVZEAPALCD-UHFFFAOYSA-N 0.000 description 2
- NBEMQPLNBYYUAZ-UHFFFAOYSA-N ethyl acetate;propan-2-one Chemical compound CC(C)=O.CCOC(C)=O NBEMQPLNBYYUAZ-UHFFFAOYSA-N 0.000 description 2
- 230000001077 hypotensive effect Effects 0.000 description 2
- 230000003285 pharmacodynamic effect Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- KPZGRMZPZLOPBS-UHFFFAOYSA-N 1,3-dichloro-2,2-bis(chloromethyl)propane Chemical compound ClCC(CCl)(CCl)CCl KPZGRMZPZLOPBS-UHFFFAOYSA-N 0.000 description 1
- 125000000022 2-aminoethyl group Chemical group [H]C([*])([H])C([H])([H])N([H])[H] 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- FCLZCOCSZQNREK-UHFFFAOYSA-N Pyrrolidine, hydrochloride Chemical compound Cl.C1CCNC1 FCLZCOCSZQNREK-UHFFFAOYSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000001721 carbon Chemical group 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- HDITUCONWLWUJR-UHFFFAOYSA-N diethylazanium;chloride Chemical compound [Cl-].CC[NH2+]CC HDITUCONWLWUJR-UHFFFAOYSA-N 0.000 description 1
- LJQKCYFTNDAAPC-UHFFFAOYSA-N ethanol;ethyl acetate Chemical compound CCO.CCOC(C)=O LJQKCYFTNDAAPC-UHFFFAOYSA-N 0.000 description 1
- YKWNUSJLICDQEO-UHFFFAOYSA-N ethoxyethane;propan-2-ol Chemical compound CC(C)O.CCOCC YKWNUSJLICDQEO-UHFFFAOYSA-N 0.000 description 1
- HWJHWSBFPPPIPD-UHFFFAOYSA-N ethoxyethane;propan-2-one Chemical compound CC(C)=O.CCOCC HWJHWSBFPPPIPD-UHFFFAOYSA-N 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 125000004193 piperazinyl group Chemical group 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- HHAVHBDPWSUKHZ-UHFFFAOYSA-N propan-2-ol;propan-2-one Chemical compound CC(C)O.CC(C)=O HHAVHBDPWSUKHZ-UHFFFAOYSA-N 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 238000005956 quaternization reaction Methods 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000002048 spasmolytic effect Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/04—Production of frozen sweets, e.g. ice-cream
- A23G9/08—Batch production
- A23G9/12—Batch production using means for stirring the contents in a non-moving container
Landscapes
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Confectionery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT670367 | 1967-01-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO118495B true NO118495B (US20020193084A1-20021219-M00002.png) | 1970-01-05 |
Family
ID=11121687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO171205A NO118495B (US20020193084A1-20021219-M00002.png) | 1967-01-02 | 1967-12-29 |
Country Status (10)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA72442B (en) * | 1971-02-05 | 1972-10-25 | Apaw Sa | Automatic ice-cream machine |
| US3958968A (en) * | 1974-03-28 | 1976-05-25 | Yoshisada Hosaka | Ice cream freezer |
| CH646841A5 (en) * | 1980-05-30 | 1984-12-28 | Alfredo Cavalli | Ice-cream machine for domestic use |
| US4450692A (en) * | 1982-09-30 | 1984-05-29 | Magic Chef, Inc. | Apparatus for making frozen food products |
| IT8320690V0 (it) * | 1983-02-04 | 1983-02-04 | I P E Nuova Bialetti Ind Prodo | Gelatiera ad uso domestico. |
| IT1170125B (it) * | 1983-04-13 | 1987-06-03 | I P E Nuova Bialetti Ind Prodo | Procedimento ed apparecchiatura per la preparazione del gelato |
| US4708489A (en) * | 1984-06-04 | 1987-11-24 | Wizards Ice Cream & Confectionery Shoppe, Ltd. | Blending machine |
| IT8521308V0 (it) * | 1985-04-02 | 1985-04-02 | Cavalli Alfredo | Apparecchiatura perfezionata per la produzione a livello domestico di gelato e simili prodotti freddi. |
| AT386321B (de) * | 1986-01-16 | 1988-08-10 | Philips Nv | Mischwerkzeug fuer eine speiseeismaschine |
| JPH0663945B2 (ja) * | 1988-08-26 | 1994-08-22 | 株式会社日立製作所 | 攪拌装置 |
| IT1399019B1 (it) * | 2009-05-14 | 2013-04-05 | G S G Srl | Vasca cilindrica perfezionata per il trattamento termico di una miscela alimentare in genere e macchina per la produzione di miscele alimentari provvista di questa vasca cilindrica |
| IT201800005095U1 (it) * | 2018-12-20 | 2020-06-20 | Ali Group Srl Carpigiani | Macchina per la realizzazione di prodotti alimentari liquidi o semiliquidi. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1756261A (en) * | 1927-08-15 | 1930-04-29 | H H Miller Ind Company | Freezing apparatus |
| US2577916A (en) * | 1947-10-11 | 1951-12-11 | Michael A Rollman | Ice-cream freezer |
| US3029613A (en) * | 1960-08-18 | 1962-04-17 | Morris M Lande | Ice cream freezing apparatus |
| US3138008A (en) * | 1962-04-19 | 1964-06-23 | William C Thompson | Means for making frozen products including a detachable cover |
-
1967
- 1967-12-28 AT AT1172867A patent/AT282667B/de not_active IP Right Cessation
- 1967-12-28 DE DE1967A0057820 patent/DE1601075B2/de active Granted
- 1967-12-28 AT AT1128569A patent/AT293453B/de not_active IP Right Cessation
- 1967-12-29 DK DK662767AA patent/DK123791B/da unknown
- 1967-12-29 NO NO171205A patent/NO118495B/no unknown
- 1967-12-30 ES ES349332A patent/ES349332A1/es not_active Expired
-
1968
- 1968-01-02 NL NL6800005A patent/NL6800005A/xx unknown
- 1968-01-02 FR FR1580832D patent/FR1580832A/fr not_active Expired
- 1968-01-02 US US695154A patent/US3465540A/en not_active Expired - Lifetime
- 1968-01-02 BE BE708845D patent/BE708845A/xx not_active IP Right Cessation
- 1968-01-03 CH CH4968A patent/CH468604A/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH468604A (de) | 1969-02-15 |
| AT282667B (de) | 1970-07-10 |
| DE1601075A1 (de) | 1970-11-05 |
| DE1601075B2 (de) | 1976-10-14 |
| US3465540A (en) | 1969-09-09 |
| ES349332A1 (es) | 1969-04-01 |
| AT293453B (de) | 1971-10-11 |
| BE708845A (US20020193084A1-20021219-M00002.png) | 1968-05-16 |
| FR1580832A (US20020193084A1-20021219-M00002.png) | 1969-09-12 |
| NL6800005A (US20020193084A1-20021219-M00002.png) | 1968-07-03 |
| DK123791B (da) | 1972-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69634254T2 (de) | Verwendung von oxidosqualencyclasehemmer zur senkung des cholesterinblutspiegels | |
| US2629736A (en) | Basically substituted n-alkyl derivatives of alpha, beta, beta-triarylpropionamides | |
| DE69730490T2 (de) | Aminoheterocyclische verbindungen als antithrombotisches oder antikoagulierendes mittel | |
| CN1330657C (zh) | 哌啶和哌嗪衍生物 | |
| AT398201B (de) | Neue chinolinsulfonaminoderivate und verfahren zu deren herstellung sowie pharmazeutische zusammensetzung | |
| CH405314A (de) | Verfahren zur Herstellung von Indolylverbindungen | |
| DE68904364T2 (de) | (aza)naphtalensultam-derivate, verfahren zu deren herstellung und arzneimittel, die sie enthalten. | |
| NO122814B (US20020193084A1-20021219-M00002.png) | ||
| NO118495B (US20020193084A1-20021219-M00002.png) | ||
| US2629719A (en) | Aminoalkyl thioxanthene oxides and the production thereof | |
| DE69006872T2 (de) | 1H,3H,7-Pyrrolo [1,2-c]thiazolcarbonsäureamid-Derivate, ihre Herstellung und diese enthaltende pharmazeutische Zubereitungen. | |
| DE69733427T2 (de) | Tetrahydrobezindol derivate | |
| DE2311570A1 (de) | 4-aminochinoline, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen | |
| SU526292A3 (ru) | Способ получени производных 8-азапурин-6-она | |
| DE69127976T2 (de) | Tropolonderivate und pharmazeutische zubereitungen davon zur vorbeugung und behandlung von ischämischen krankheiten | |
| EP0044989B1 (de) | Neue, in 5-Stellung substituierte 5,10-Dihydro-11H-dibenzo (b,e)(1,4)diazepin-11-one, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel | |
| SU1251805A3 (ru) | Способ получени гетероциклических амидов | |
| US2872453A (en) | Indole derivatives | |
| US2694705A (en) | Nx c c ox a a | |
| US3479346A (en) | N-acyl-n- (and n,n-bis-) ((1-piperidyl)-lower-alkyl)amines | |
| DE69300296T2 (de) | Thiochromanderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen. | |
| DE68926320T2 (de) | Pyrazoloacridonderivate mit Antitumoraktivität | |
| DE3723648A1 (de) | Indol-derivate, ihre herstellung und sie enthaltende arzneimittel | |
| PL69663B1 (US20020193084A1-20021219-M00002.png) | ||
| DE1720033A1 (de) | Neue Indolderivate und Verfahren zu ihrer Herstellung |
