NL99649C - - Google Patents

Info

Publication number
NL99649C
NL99649C NL99649DA NL99649C NL 99649 C NL99649 C NL 99649C NL 99649D A NL99649D A NL 99649DA NL 99649 C NL99649 C NL 99649C
Authority
NL
Netherlands
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of NL99649C publication Critical patent/NL99649C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657154Cyclic esteramides of oxyacids of phosphorus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NL99649D 1956-12-20 NL99649C (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEA26234A DE1054997B (de) 1956-12-20 1956-12-20 Verfahren zur Herstellung von cyclischen Thiophosphorsaeure-esteramiden
DEA28444A DE1116672B (de) 1956-12-20 1957-12-04 Verfahren zur Herstellung von cyclischen Phosphorsaeure- und Thiophosphorsaeureesteramiden
DEA24298A DE1057119B (de) 1956-12-20 1957-12-04 Verfahren zur Herstellung von cyclischen Phosphorsaeure-esteramiden

Publications (1)

Publication Number Publication Date
NL99649C true NL99649C (es)

Family

ID=27208860

Family Applications (3)

Application Number Title Priority Date Filing Date
NL99649D NL99649C (es) 1956-12-20
NL222157D NL222157A (es) 1956-12-20
NL99688D NL99688C (es) 1956-12-20

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL222157D NL222157A (es) 1956-12-20
NL99688D NL99688C (es) 1956-12-20

Country Status (7)

Country Link
US (2) US3018302A (es)
BE (2) BE563332A (es)
CH (3) CH361279A (es)
DE (3) DE1054997B (es)
FR (2) FR1246708A (es)
GB (2) GB812651A (es)
NL (3) NL99688C (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270093A (en) * 1963-04-19 1966-08-30 Tenneco Chem Omicron, omicron-neopentylene-nu-diethylphosphoroamidothioate
US3286001A (en) * 1963-06-07 1966-11-15 Continental Oil Co Reaction products of organophosphorus monohalides with mercaptoalkylamines
US3335129A (en) * 1963-11-21 1967-08-08 Wyandotte Chemicals Corp Phosphoramidates
DE2110333A1 (de) * 1971-03-04 1972-09-14 Audi Nsu Auto Union Ag Kreiskolben-Brennkraftmaschine
PL100390B1 (pl) 1975-10-06 1978-09-30 Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej
DE3132221A1 (de) * 1981-08-14 1983-05-19 Behringwerke Ag, 3550 Marburg Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung
DE3133077A1 (de) * 1981-08-21 1983-03-10 Henkel KGaA, 4000 Düsseldorf Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen
US5227374A (en) * 1982-11-12 1993-07-13 Mead Johnson & Company Lyophilized cyclophosphamide
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide
US4659699A (en) * 1983-08-22 1987-04-21 Cetus-Ben Venue Therapeutics Process for freeze drying cyclophosphamide
US4879286A (en) * 1987-01-28 1989-11-07 Lyphomed, Inc. Cyclophosphamide
IT1251472B (it) * 1991-09-12 1995-05-15 Boehringer Mannheim Italia Ossaazafosforine utili come agenti antitumorali, un processo per la loro preparazione e composizioni farmaceutiche che le contengono
DE19739159C1 (de) * 1997-09-06 1999-01-28 Asta Medica Ag Verfahren zur Herstellung von Oxazaphosphorin-2-aminen
US6312662B1 (en) * 1998-03-06 2001-11-06 Metabasis Therapeutics, Inc. Prodrugs phosphorus-containing compounds
JP4741725B2 (ja) 1998-03-06 2011-08-10 メタベイシス・セラピューティクス・インコーポレーテッド リン含有化合物のための新規なプロドラッグ
US7205404B1 (en) * 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
CZ20013180A3 (cs) * 1999-03-05 2002-02-13 Metabasis Therapeutics, Inc. Nové cyklické fosforamidáty, způsob jejich přípravy a farmaceutické kompozice, které je obsahují
US6752981B1 (en) 1999-09-08 2004-06-22 Metabasis Therapeutics, Inc. Prodrugs for liver specific drug delivery
US7829084B2 (en) 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
AU2003299492B2 (en) * 2002-05-13 2010-06-10 Metabasis Therapeutics, Inc. Cyclic prodrugs of PMEA one of its analogues
EP1504014B1 (en) * 2002-05-13 2015-12-02 Metabasis Therapeutics, Inc. Process for preparation of cyclic prodrugs of pmea and pmpa
US7151092B2 (en) * 2002-10-31 2006-12-19 Metabasis Therapeutics, Inc. Cytarabine monophosphate prodrugs
US20050182252A1 (en) * 2004-02-13 2005-08-18 Reddy K. R. Novel 2'-C-methyl nucleoside derivatives
JP5142716B2 (ja) * 2004-06-08 2013-02-13 リガンド・ファーマシューティカルズ・インコーポレイテッド サイクリックエステルのルイス酸介在合成法
AU2015217221A1 (en) 2014-02-13 2016-08-11 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
KR20170008252A (ko) 2014-05-09 2017-01-23 아우로메딕스 파마 엘엘씨 사이클로포스파미드 액상 농축 제제
EP3164136A4 (en) 2014-07-02 2018-04-04 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
US10849916B2 (en) 2014-07-11 2020-12-01 Dr. Reddys Laboratories Limited Stable liquid formulations of cyclophosphamide and its impurities
WO2016005962A2 (en) 2014-07-11 2016-01-14 Dr. Reddy’S Laboratories Limited Stable liquid formulations of cyclophosphamide and processes
WO2016046797A1 (en) 2014-09-26 2016-03-31 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
EP3236903B1 (en) 2014-12-23 2021-04-21 Intellectual Property Associates, LLC Methods and formulations for transdermal administration
WO2016156927A1 (en) 2015-04-02 2016-10-06 PRZEDSIĘBIORSTWO PRODUKCYJNO-WDROŻENIOWE IFOTAM Sp. z o.o. Method of production of n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxazaphosphorine-2-amine 2-oxide
WO2017207719A1 (en) 2016-06-02 2017-12-07 Amneal Pharmaceuticals Company Gmbh Cyclophosphamide composition and method for preparation thereof
EP3681479B1 (en) 2017-09-15 2024-01-31 Dyve Biosciences, Inc. Sodium bicarbonate for use in the treatment of gout and related disorders
AU2019207625A1 (en) 2018-01-09 2020-07-30 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1065418B (de) * 1953-03-21 1959-09-17 Montecatini Soc. Gen. per 1'Industria Mineraria e Chimica, Mailand (Italien) Verfahren zur Herstellung von heterocyclischen Phosphorverbindungen
BE575869A (es) * 1958-02-20 1900-01-01

Also Published As

Publication number Publication date
BE554888A (es)
FR1246708A (fr) 1960-11-25
CH369451A (de) 1963-05-31
BE563332A (es)
DE1054997B (de) 1959-04-16
DE1116672B (de) 1961-11-09
CH370406A (de) 1963-07-15
DE1057119B (de) 1959-05-14
GB812651A (en) 1959-04-29
US3074992A (en) 1963-01-22
CH361279A (de) 1962-04-15
FR75178E (es) 1961-09-08
GB853044A (en) 1960-11-02
NL222157A (es)
US3018302A (en) 1962-01-23
NL99688C (es)

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