NL8601043A - Anti-psychotische benzisothiazool-s-oxide-verbinding. - Google Patents

Anti-psychotische benzisothiazool-s-oxide-verbinding. Download PDF

Info

Publication number
NL8601043A
NL8601043A NL8601043A NL8601043A NL8601043A NL 8601043 A NL8601043 A NL 8601043A NL 8601043 A NL8601043 A NL 8601043A NL 8601043 A NL8601043 A NL 8601043A NL 8601043 A NL8601043 A NL 8601043A
Authority
NL
Netherlands
Prior art keywords
compound
psychotic
bmy
formula
acid addition
Prior art date
Application number
NL8601043A
Other languages
English (en)
Dutch (nl)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NL8601043A publication Critical patent/NL8601043A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL8601043A 1985-04-24 1986-04-23 Anti-psychotische benzisothiazool-s-oxide-verbinding. NL8601043A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/726,449 US4656173A (en) 1985-04-24 1985-04-24 Antipsychotic benzisothiazole S-oxide compound
US72644985 1985-04-24

Publications (1)

Publication Number Publication Date
NL8601043A true NL8601043A (nl) 1986-11-17

Family

ID=24918649

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8601043A NL8601043A (nl) 1985-04-24 1986-04-23 Anti-psychotische benzisothiazool-s-oxide-verbinding.

Country Status (26)

Country Link
US (1) US4656173A (de)
JP (1) JPH0764842B2 (de)
KR (1) KR900000372B1 (de)
CN (1) CN1017528B (de)
AT (1) AT394719B (de)
AU (1) AU592787B2 (de)
BE (1) BE904662A (de)
CA (1) CA1247102A (de)
CH (1) CH666034A5 (de)
DE (1) DE3613739C2 (de)
DK (1) DK187686A (de)
EG (1) EG18002A (de)
ES (1) ES8708228A1 (de)
FI (1) FI84604C (de)
FR (1) FR2581064B1 (de)
GB (1) GB2174393B (de)
GR (1) GR861063B (de)
HU (1) HU195654B (de)
IE (1) IE59182B1 (de)
IT (1) IT1208600B (de)
LU (1) LU86405A1 (de)
MY (1) MY102041A (de)
NL (1) NL8601043A (de)
PT (1) PT82450B (de)
SE (1) SE462163B (de)
ZA (1) ZA861531B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
EP0350145A3 (de) * 1988-04-28 1990-07-04 Yamanouchi Pharmaceutical Co. Ltd. Pyridylthiazolidine carboxamide Derivative und ihreZwischenprodukte und deren Herstellung
US5077295A (en) * 1988-09-16 1991-12-31 Pfizer Inc. Antipsychoic 4-(4-(3-benzisothiazolyl)-1-piperazinyl)buytl bridged bicycle imides
US4956368A (en) * 1989-07-24 1990-09-11 Bristol-Myers Company Metabolites and prodrug formulations of 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione
US4968792A (en) * 1989-09-25 1990-11-06 American Home Products Corporation Psychotropic benzisothiazole derivatives
US5162321A (en) * 1989-12-20 1992-11-10 Adir Et Compagnie 1-naphthyl piperazines useful as 5-HT1A receptor ligands
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
CH582699A5 (de) * 1973-03-26 1976-12-15 Sandoz Ag
AT342057B (de) * 1974-04-25 1978-03-10 Thomae Gmbh Dr K Verfahren zur herstellung von neuen 3-piperazino-isochinolinen und deren salzen
FI753625A (de) * 1975-01-06 1976-07-07 Spofa Vereinigte Pharma Werke
JPS51144735A (en) * 1975-06-06 1976-12-13 Nippon Nohyaku Co Ltd A remedy for hepatic failure
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives

Also Published As

Publication number Publication date
IE861083L (en) 1986-10-24
ES8708228A1 (es) 1987-10-01
FI861668A0 (fi) 1986-04-21
SE8601883D0 (sv) 1986-04-23
PT82450A (en) 1986-05-01
ES554284A0 (es) 1987-10-01
DK187686A (da) 1986-10-25
IE59182B1 (en) 1994-01-26
GB2174393B (en) 1989-02-01
GR861063B (en) 1986-09-01
CN86102742A (zh) 1987-02-04
ZA861531B (en) 1986-10-29
GB2174393A (en) 1986-11-05
FI84604C (fi) 1991-12-27
AU592787B2 (en) 1990-01-25
ATA110486A (de) 1991-11-15
EG18002A (en) 1991-08-30
JPH0764842B2 (ja) 1995-07-12
KR860008174A (ko) 1986-11-12
FI861668A (fi) 1986-10-25
CN1017528B (zh) 1992-07-22
HUT42088A (en) 1987-06-29
HU195654B (en) 1988-06-28
BE904662A (fr) 1986-10-23
DE3613739C2 (de) 1993-12-09
MY102041A (en) 1992-02-29
CA1247102A (en) 1988-12-20
DK187686D0 (da) 1986-04-23
SE462163B (sv) 1990-05-14
GB8609932D0 (en) 1986-05-29
AT394719B (de) 1992-06-10
PT82450B (pt) 1988-11-30
KR900000372B1 (ko) 1990-01-25
JPS61251683A (ja) 1986-11-08
IT8620187A0 (it) 1986-04-23
DE3613739A1 (de) 1986-11-20
US4656173A (en) 1987-04-07
FR2581064A1 (fr) 1986-10-31
IT1208600B (it) 1989-07-10
FR2581064B1 (fr) 1988-09-16
FI84604B (fi) 1991-09-13
CH666034A5 (de) 1988-06-30
LU86405A1 (fr) 1986-11-05
AU5612186A (en) 1986-10-30
SE8601883L (sv) 1986-10-25

Similar Documents

Publication Publication Date Title
KR101151647B1 (ko) Ｇｓｋ-3 저해제로서의 티아디아졸리디논
US6380214B1 (en) Heterocyclic derivatives useful as anticancer agents
JPH0517457A (ja) ベンズイソチアゾールおよびベンズイソキサゾールピペラジン誘導体
EP1581528A1 (de) Piperidinyl-thiazol-carbonsäure-derivate als angiogenesis inhibitoren
SK5952002A3 (en) Pyrrole derivatives as phosphodiesterase vii inhibitor, the use thereof and pharmaceutical composition comprising the same
KR100189313B1 (ko) 피롤릴벤즈 이미다졸 유도체
NL8601043A (nl) Anti-psychotische benzisothiazool-s-oxide-verbinding.
KR20010108089A (ko) 신규한 2-(ｎ-시아노이미노)티아졸리딘-4-온 유도체
WO2006082821A1 (ja) ヘルペスウイルスが関与する疾患の予防若しくは治療剤
SK5942002A3 (en) Isoxazole derivatives to be used as phosphodiesterase vii inhibitors, use thereof and pharmaceutical composition comprising the same
CN107001276B (zh) 一种尿酸转运蛋白抑制剂的钠盐及其结晶形式
WO1989003682A1 (en) Benzothiazine dioxide derivatives
CN102086212B (zh) 抗真菌剂-2，3，4，5-四氢-4H-苯并[b]噻喃并[4，3-c]吡唑-2-甲酰胺衍生物
JP2021127289A (ja) 縮合ピリミジン誘導体
HU214337B (hu) Eljárás 1,3,4-tiadiazin-2-on-származékok és az azokat tartalmazó gyógyszer készítmények előállítására
KR102660247B1 (ko) 4-(나프탈렌-1-일)-4h-1, 2, 4-트리아졸계 화합물의 결정 형태, 염 형태 및 이의 제조방법
HU201084B (en) Basically substituted 5-halothienoisothiazol-3(2h)-one-1,1-dioxides, process for their preparation and pharmaceutical compositions containing them
CN116535361A (zh) 取代羟基嘧啶类黄嘌呤氧化酶抑制剂及其制法和药物用途
LV10920B (en) Lysine salt of 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide
US20060122177A1 (en) Phenylpiperazines with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites

Legal Events

Date Code Title Description
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: BRISTOL-MYERS SQUIBB COMPANY

BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BN A decision not to publish the application has become irrevocable