NL8500370A - Diazepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. - Google Patents
Diazepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. Download PDFInfo
- Publication number
- NL8500370A NL8500370A NL8500370A NL8500370A NL8500370A NL 8500370 A NL8500370 A NL 8500370A NL 8500370 A NL8500370 A NL 8500370A NL 8500370 A NL8500370 A NL 8500370A NL 8500370 A NL8500370 A NL 8500370A
- Authority
- NL
- Netherlands
- Prior art keywords
- acid addition
- addition salt
- carbon atoms
- group
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 21
- 239000000825 pharmaceutical preparation Substances 0.000 title claims description 5
- 238000002360 preparation method Methods 0.000 title description 6
- 150000001875 compounds Chemical class 0.000 claims description 74
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- 150000003839 salts Chemical class 0.000 claims description 43
- 125000004432 carbon atom Chemical group C* 0.000 claims description 39
- 125000000217 alkyl group Chemical group 0.000 claims description 25
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 19
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 15
- 239000012458 free base Substances 0.000 claims description 10
- 229910052757 nitrogen Inorganic materials 0.000 claims description 8
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 8
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- ZOOSILUVXHVRJE-UHFFFAOYSA-N cyclopropanecarbonyl chloride Chemical compound ClC(=O)C1CC1 ZOOSILUVXHVRJE-UHFFFAOYSA-N 0.000 description 2
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- BSYFXFLGOGQHFU-UHFFFAOYSA-N pyrrolo[2,3-g][1,2]benzodiazepine Chemical class N1=NC=CC=C2C3=NC=CC3=CC=C21 BSYFXFLGOGQHFU-UHFFFAOYSA-N 0.000 description 2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH86384 | 1984-02-22 | ||
| CH86384 | 1984-02-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8500370A true NL8500370A (nl) | 1985-09-16 |
Family
ID=4196936
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8500370A NL8500370A (nl) | 1984-02-22 | 1985-02-11 | Diazepinoindolen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4673674A (cs) |
| JP (1) | JPS60202887A (cs) |
| AT (1) | AT388379B (cs) |
| BE (1) | BE901725A (cs) |
| CA (1) | CA1271193A (cs) |
| DE (1) | DE3505017A1 (cs) |
| DK (1) | DK78385A (cs) |
| ES (2) | ES8706681A1 (cs) |
| FI (1) | FI79316C (cs) |
| FR (1) | FR2609715B1 (cs) |
| GB (1) | GB2154584B (cs) |
| GR (1) | GR850443B (cs) |
| HU (1) | HU193083B (cs) |
| IL (1) | IL74388A (cs) |
| IT (1) | IT1199949B (cs) |
| LU (1) | LU85778A1 (cs) |
| MY (1) | MY100083A (cs) |
| NL (1) | NL8500370A (cs) |
| PH (1) | PH22247A (cs) |
| PL (2) | PL144329B1 (cs) |
| PT (1) | PT79990B (cs) |
| SE (1) | SE8500822L (cs) |
| ZA (1) | ZA851373B (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3635071A1 (de) * | 1986-10-15 | 1988-04-28 | Autoflug Gmbh | Rueckenlehnenverriegelung fuer einen mit sicherheitsgurten ausgeruesteten fahrzeugsitz |
| NZ521389A (en) | 2000-03-14 | 2005-06-24 | Upjohn Co | 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole compounds |
| EP2351578B1 (en) * | 2005-06-27 | 2017-01-18 | GlaxoSmithKline Biologicals S.A. | Process for manufacturing vaccines |
| HU230880B1 (hu) * | 2015-04-15 | 2018-11-29 | Richter Gedeon Nyrt | Indol származékok |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1593146A (en) * | 1976-11-05 | 1981-07-15 | Beecham Group Ltd | Octahydro-quinolizinyl benzamide derivatives |
| US4210590A (en) * | 1978-01-06 | 1980-07-01 | Mcneil Laboratories, Incorporated | Reduction of indole compounds to indoline compounds |
| CH649553A5 (de) * | 1982-05-06 | 1985-05-31 | Sandoz Ag | Azepinoindole und verfahren zu deren herstellung. |
-
1985
- 1985-02-11 NL NL8500370A patent/NL8500370A/nl not_active Application Discontinuation
- 1985-02-11 HU HU85510A patent/HU193083B/hu not_active IP Right Cessation
- 1985-02-13 BE BE1/11188A patent/BE901725A/fr unknown
- 1985-02-14 DE DE19853505017 patent/DE3505017A1/de not_active Withdrawn
- 1985-02-14 PH PH31856A patent/PH22247A/en unknown
- 1985-02-19 GB GB08504179A patent/GB2154584B/en not_active Expired
- 1985-02-20 GR GR850443A patent/GR850443B/el unknown
- 1985-02-20 LU LU85778A patent/LU85778A1/fr unknown
- 1985-02-20 FI FI850702A patent/FI79316C/fi not_active IP Right Cessation
- 1985-02-20 PT PT79990A patent/PT79990B/pt unknown
- 1985-02-20 SE SE8500822A patent/SE8500822L/xx not_active Application Discontinuation
- 1985-02-20 ES ES540559A patent/ES8706681A1/es not_active Expired
- 1985-02-20 DK DK78385A patent/DK78385A/da not_active Application Discontinuation
- 1985-02-20 IT IT47704/85A patent/IT1199949B/it active
- 1985-02-20 IL IL74388A patent/IL74388A/xx unknown
- 1985-02-21 JP JP60034261A patent/JPS60202887A/ja active Pending
- 1985-02-21 PL PL1985252065A patent/PL144329B1/pl unknown
- 1985-02-21 PL PL1985268394A patent/PL146274B1/pl unknown
- 1985-02-21 CA CA000474852A patent/CA1271193A/en not_active Expired - Lifetime
- 1985-02-21 AT AT0052285A patent/AT388379B/de not_active IP Right Cessation
- 1985-02-21 US US06/704,040 patent/US4673674A/en not_active Expired - Fee Related
- 1985-02-22 ZA ZA851373A patent/ZA851373B/xx unknown
-
1986
- 1986-05-16 ES ES555042A patent/ES8707204A1/es not_active Expired
-
1987
- 1987-09-25 MY MYPI87001944A patent/MY100083A/en unknown
- 1987-11-23 FR FR878716324A patent/FR2609715B1/fr not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BV | The patent application has lapsed |