NL8320115A - Werkwijze voor het bereiden van geimmobiliseerde l-asparaginase-preparaten voor een therapie van leukemie. - Google Patents

Werkwijze voor het bereiden van geimmobiliseerde l-asparaginase-preparaten voor een therapie van leukemie. Download PDF

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Publication number
NL8320115A
NL8320115A NL8320115A NL8320115A NL8320115A NL 8320115 A NL8320115 A NL 8320115A NL 8320115 A NL8320115 A NL 8320115A NL 8320115 A NL8320115 A NL 8320115A NL 8320115 A NL8320115 A NL 8320115A
Authority
NL
Netherlands
Prior art keywords
gel
polyvinyl alcohol
enzyme
water
asparaginase
Prior art date
Application number
NL8320115A
Other languages
English (en)
Dutch (nl)
Original Assignee
Nippon Oil Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Oil Co Ltd filed Critical Nippon Oil Co Ltd
Publication of NL8320115A publication Critical patent/NL8320115A/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/084—Polymers containing vinyl alcohol units
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/098—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer formed in the presence of the enzymes or microbial cells
NL8320115A 1982-04-21 1983-04-21 Werkwijze voor het bereiden van geimmobiliseerde l-asparaginase-preparaten voor een therapie van leukemie. NL8320115A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP57065466A JPS58183626A (ja) 1982-04-21 1982-04-21 白血病治療用ｌ−アスパラギナ−ゼ固定化剤
JP6546682 1982-04-21
JP8300126 1983-04-21
PCT/JP1983/000126 WO1983003763A1 (en) 1982-04-21 1983-04-21 Process for preparing l-asparaginase-immobilizing agent for teating leucemia

Publications (1)

Publication Number Publication Date
NL8320115A true NL8320115A (nl) 1984-03-01

Family

ID=13287919

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8320115A NL8320115A (nl) 1982-04-21 1983-04-21 Werkwijze voor het bereiden van geimmobiliseerde l-asparaginase-preparaten voor een therapie van leukemie.

Country Status (5)

Country Link
US (1) US4617271A (de)
JP (1) JPS58183626A (de)
CH (1) CH659393A5 (de)
NL (1) NL8320115A (de)
WO (1) WO1983003763A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60156472A (ja) * 1984-01-26 1985-08-16 旭メデイカル株式会社 白血病治療装置
JPS61104787A (ja) * 1984-10-26 1986-05-23 Toyo Jozo Co Ltd Ｐｖａゲルによる多孔性固定化酵素含有物の製法
US5723588A (en) * 1986-11-04 1998-03-03 Protein Polymer Technologies, Inc. Protein-enriched thermoplastics
US4929042A (en) * 1986-11-28 1990-05-29 Fuji Photo Film Co., Ltd. Variable acoustical deflection of an optical wave in an optical waveguide
JPH0612993B2 (ja) * 1987-08-10 1994-02-23 株式会社クラレ 球状の微生物固定化成形物の製造法
US5089407A (en) * 1987-12-11 1992-02-18 Monsanto Company Encapsulation of biological material in non-ionic polymer beads
US5053453A (en) * 1988-11-01 1991-10-01 Baxter International Inc. Thromboresistant materials and methods for making same
DE10053611A1 (de) * 2000-10-28 2002-05-02 Inst Textil & Faserforschung Bioresorbierbare Nervenleitschiene
FI20070455A0 (fi) * 2007-06-08 2007-06-08 Reagena Ltd Oy Menetelmä syöpäsairauksien tai tulehdussairauksien hoitoon
CN112704774B (zh) * 2020-12-24 2023-01-10 苏州森康微球医疗科技有限公司 一种填装有固定化l-天冬酰胺酶的血液灌流器及其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1383216A (en) * 1972-05-03 1975-02-05 Polymeric Enzymes Inc Stabilization of enzymes
JPS5742607B2 (de) * 1973-07-06 1982-09-09
JPS5619994B2 (de) * 1973-09-14 1981-05-11
JPS528071A (en) * 1975-07-08 1977-01-21 Kuraray Co Method of producing polyvinyl alcohol film
JPS52151723A (en) * 1976-06-12 1977-12-16 Green Cross Corp:The L-asparaginase preparations and container for same

Also Published As

Publication number Publication date
JPS58183626A (ja) 1983-10-26
CH659393A5 (de) 1987-01-30
WO1983003763A1 (en) 1983-11-10
US4617271A (en) 1986-10-14

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed