NL8220181A - Geimmobiliseerd pepsine voor gebruik in de verwijdering van immuuncomplex uit bloed, en een werkwijze voor het verwijderen van immuuncomplex uit bloed door gebruik van het geimmobiliseerde pepsine. - Google Patents

Geimmobiliseerd pepsine voor gebruik in de verwijdering van immuuncomplex uit bloed, en een werkwijze voor het verwijderen van immuuncomplex uit bloed door gebruik van het geimmobiliseerde pepsine. Download PDF

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Publication number
NL8220181A
NL8220181A NL8220181A NL8220181A NL8220181A NL 8220181 A NL8220181 A NL 8220181A NL 8220181 A NL8220181 A NL 8220181A NL 8220181 A NL8220181 A NL 8220181A NL 8220181 A NL8220181 A NL 8220181A
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NL
Netherlands
Prior art keywords
immobilized
pepsin
blood
immune complex
plasma
Prior art date
Application number
NL8220181A
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English (en)
Dutch (nl)
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of NL8220181A publication Critical patent/NL8220181A/nl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033Membrane, sheet, cloth, pad, lamellar or mat
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033Membrane, sheet, cloth, pad, lamellar or mat
    • B01J20/28038Membranes or mats made from fibers or filaments
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/3092Packing of a container, e.g. packing a cartridge or column
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204Inorganic carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • B01J20/3212Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268Macromolecular compounds
    • B01J20/3272Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14Enzymes or microbial cells immobilised on or in an inorganic carrier
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58Use in a single column
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/64In a syringe, pipette, e.g. tip or in a tube, e.g. test-tube or u-shape tube
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/80Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/86Sorbents applied to inner surfaces of columns or capillaries

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL8220181A 1982-05-31 1982-05-31 Geimmobiliseerd pepsine voor gebruik in de verwijdering van immuuncomplex uit bloed, en een werkwijze voor het verwijderen van immuuncomplex uit bloed door gebruik van het geimmobiliseerde pepsine. NL8220181A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/JP1982/000212 WO1983004180A1 (en) 1982-05-31 1982-05-31 Immobilized pepsin for removing blood immune complex and method for removing blood immune complex using immobilized pepsin
JP8200212 1982-05-31

Publications (1)

Publication Number Publication Date
NL8220181A true NL8220181A (nl) 1984-04-02

Family

ID=13762277

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8220181A NL8220181A (nl) 1982-05-31 1982-05-31 Geimmobiliseerd pepsine voor gebruik in de verwijdering van immuuncomplex uit bloed, en een werkwijze voor het verwijderen van immuuncomplex uit bloed door gebruik van het geimmobiliseerde pepsine.

Country Status (10)

Country Link
US (1) US4608253A (de)
EP (1) EP0110995B1 (de)
BE (1) BE898329A (de)
CA (1) CA1222452A (de)
CH (1) CH664496A5 (de)
DE (1) DE3249491T1 (de)
GB (1) GB2131028B (de)
NL (1) NL8220181A (de)
SE (1) SE459556B (de)
WO (1) WO1983004180A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4627915A (en) * 1983-04-06 1986-12-09 Asahi Kasei Kogyo Kabushiki Kaisha Absorbent of autoantibody and immune complexes, adsorbing device and blood purifying apparatus comprising the same
IT1186766B (it) * 1985-11-08 1987-12-16 Sclavo Spa Metodo per la preparazione di immunoglobuline per uso endovenoso
CA1327963C (en) * 1987-09-08 1994-03-22 Ryuichi Yokohari Autoantibody adsorbent and apparatus for removing autoantibodies using the same
AT391810B (de) * 1988-02-26 1990-12-10 Immuno Ag Verwendung von chymotrypsin zum unwirksammachen des praekallikrein-aktivators
US5593897A (en) * 1988-04-04 1997-01-14 Northwestern University Binding of immune complexes by modified forms of C-reactive protein
EP3669888A1 (de) * 2018-12-20 2020-06-24 Gambro Lundia AB Extrakorporale vorrichtungen für verfahren zur behandlung von erkrankungen im zusammenhang mit zytoplasmischen anti-neutrophil-antikörpern

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3746622A (en) * 1971-05-12 1973-07-17 Xerox Corp Composition and process
JPS5138195A (en) * 1974-09-27 1976-03-30 Osaka Prefecture Reezakonyoru anaakekakohoho
JPS52151723A (en) * 1976-06-12 1977-12-16 Green Cross Corp:The L-asparaginase preparations and container for same
JPS52155888A (en) * 1976-06-22 1977-12-24 Mitsui Toatsu Chemicals Device for continuously removing material in blood flow
DE2828549A1 (de) * 1978-06-29 1980-01-17 Fresenius Chem Pharm Ind Apparat fuer blutbehandlung
DE2840655C2 (de) * 1978-09-19 1982-06-16 Dr. Eduard Fresenius, Chemisch-pharmazeutische Industrie KG Apparatebau KG, 6380 Bad Homburg Vorrichtung zur Blutentgiftung
IT1122388B (it) * 1979-08-01 1986-04-23 Anic Spa Procedimento per la preparazione di materiali biocompatibili tramite l'immobilizzazione superficiale di apirasi
JPS5713266A (en) * 1980-06-27 1982-01-23 Diesel Kiki Co Ltd Fuel injection device
JPS6238329B1 (de) * 1982-02-09 1987-08-17 Mochida Pharm Co Ltd

Also Published As

Publication number Publication date
EP0110995A4 (de) 1984-09-13
SE8306424L (sv) 1985-05-22
EP0110995A1 (de) 1984-06-20
CA1222452A (en) 1987-06-02
GB2131028A (en) 1984-06-13
CH664496A5 (de) 1988-03-15
WO1983004180A1 (en) 1983-12-08
SE8306424D0 (sv) 1983-11-21
DE3249491T1 (de) 1984-04-19
US4608253A (en) 1986-08-26
GB8332856D0 (en) 1984-01-18
GB2131028B (en) 1985-07-03
EP0110995B1 (de) 1988-09-07
SE459556B (sv) 1989-07-17
BE898329A (fr) 1984-05-29

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