NL8202885A - Preparaten met een werking tegen virussen en methoden en produkten waarbij van dergelijke preparaten gebruik wordt gemaakt. - Google Patents
Preparaten met een werking tegen virussen en methoden en produkten waarbij van dergelijke preparaten gebruik wordt gemaakt. Download PDFInfo
- Publication number
- NL8202885A NL8202885A NL8202885A NL8202885A NL8202885A NL 8202885 A NL8202885 A NL 8202885A NL 8202885 A NL8202885 A NL 8202885A NL 8202885 A NL8202885 A NL 8202885A NL 8202885 A NL8202885 A NL 8202885A
- Authority
- NL
- Netherlands
- Prior art keywords
- acid
- mixture
- product according
- alkyl group
- carboxyl
- Prior art date
Links
- 241000700605 Viruses Species 0.000 title claims description 65
- 238000002360 preparation method Methods 0.000 title claims description 23
- 238000000034 method Methods 0.000 title claims description 15
- 230000000694 effects Effects 0.000 title description 5
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 50
- 239000000203 mixture Substances 0.000 claims description 40
- 239000002253 acid Substances 0.000 claims description 38
- 230000003253 viricidal effect Effects 0.000 claims description 35
- 239000000758 substrate Substances 0.000 claims description 23
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 21
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 21
- 150000007513 acids Chemical class 0.000 claims description 20
- 239000004744 fabric Substances 0.000 claims description 19
- 125000000217 alkyl group Chemical group 0.000 claims description 17
- -1 alkyl phenol Chemical compound 0.000 claims description 17
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 14
- 235000011090 malic acid Nutrition 0.000 claims description 13
- 239000004094 surface-active agent Substances 0.000 claims description 13
- 235000010233 benzoic acid Nutrition 0.000 claims description 12
- 235000015165 citric acid Nutrition 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 11
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 10
- 239000005711 Benzoic acid Substances 0.000 claims description 10
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 10
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 10
- 239000001630 malic acid Substances 0.000 claims description 10
- 230000000241 respiratory effect Effects 0.000 claims description 10
- 239000001384 succinic acid Substances 0.000 claims description 9
- 125000003342 alkenyl group Chemical group 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 150000002148 esters Chemical class 0.000 claims description 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 4
- ULUAUXLGCMPNKK-UHFFFAOYSA-N Sulfobutanedioic acid Chemical compound OC(=O)CC(C(O)=O)S(O)(=O)=O ULUAUXLGCMPNKK-UHFFFAOYSA-N 0.000 claims description 4
- 239000003945 anionic surfactant Substances 0.000 claims description 4
- 239000001913 cellulose Substances 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 4
- 159000000000 sodium salts Chemical class 0.000 claims description 4
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims description 3
- 125000002091 cationic group Chemical group 0.000 claims description 3
- 239000004753 textile Substances 0.000 claims description 3
- 125000001931 aliphatic group Chemical group 0.000 claims description 2
- 150000001768 cations Chemical class 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 2
- 239000003093 cationic surfactant Substances 0.000 claims 2
- 239000002736 nonionic surfactant Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 239000004745 nonwoven fabric Substances 0.000 claims 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 28
- 241000709661 Enterovirus Species 0.000 description 24
- 238000010790 dilution Methods 0.000 description 17
- 239000012895 dilution Substances 0.000 description 17
- 238000012360 testing method Methods 0.000 description 13
- 208000015181 infectious disease Diseases 0.000 description 12
- 239000000243 solution Substances 0.000 description 12
- 208000002606 Paramyxoviridae Infections Diseases 0.000 description 11
- 241000701161 unidentified adenovirus Species 0.000 description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- 230000001815 facial effect Effects 0.000 description 6
- 235000011044 succinic acid Nutrition 0.000 description 6
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 5
- 241001135569 Human adenovirus 5 Species 0.000 description 5
- 230000002779 inactivation Effects 0.000 description 5
- 230000002458 infectious effect Effects 0.000 description 5
- 229910052740 iodine Inorganic materials 0.000 description 5
- 239000011630 iodine Substances 0.000 description 5
- 150000007524 organic acids Chemical class 0.000 description 5
- 235000005985 organic acids Nutrition 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 239000003443 antiviral agent Substances 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 4
- 238000003556 assay Methods 0.000 description 4
- 150000001735 carboxylic acids Chemical class 0.000 description 4
- 230000002070 germicidal effect Effects 0.000 description 4
- 210000002345 respiratory system Anatomy 0.000 description 4
- 208000023504 respiratory system disease Diseases 0.000 description 4
- 210000003296 saliva Anatomy 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 239000000969 carrier Substances 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000006210 lotion Substances 0.000 description 3
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 235000011054 acetic acid Nutrition 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 230000000890 antigenic effect Effects 0.000 description 2
- 229940027983 antiseptic and disinfectant quaternary ammonium compound Drugs 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 230000000120 cytopathologic effect Effects 0.000 description 2
- 229940079920 digestives acid preparations Drugs 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000009931 harmful effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000003472 neutralizing effect Effects 0.000 description 2
- 230000003389 potentiating effect Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 150000003856 quaternary ammonium compounds Chemical class 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 150000003444 succinic acids Chemical class 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 241000712461 unidentified influenza virus Species 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 210000002268 wool Anatomy 0.000 description 2
- PXRKCOCTEMYUEG-UHFFFAOYSA-N 5-aminoisoindole-1,3-dione Chemical compound NC1=CC=C2C(=O)NC(=O)C2=C1 PXRKCOCTEMYUEG-UHFFFAOYSA-N 0.000 description 1
- 208000010370 Adenoviridae Infections Diseases 0.000 description 1
- 241000539677 Berant virus Species 0.000 description 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 240000006890 Erythroxylum coca Species 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- 229930182566 Gentamicin Natural products 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- 241000282560 Macaca mulatta Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 description 1
- QWZLBLDNRUUYQI-UHFFFAOYSA-M Methylbenzethonium chloride Chemical compound [Cl-].CC1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 QWZLBLDNRUUYQI-UHFFFAOYSA-M 0.000 description 1
- RSPISYXLHRIGJD-UHFFFAOYSA-N OOOO Chemical compound OOOO RSPISYXLHRIGJD-UHFFFAOYSA-N 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- BELBBZDIHDAJOR-UHFFFAOYSA-N Phenolsulfonephthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2S(=O)(=O)O1 BELBBZDIHDAJOR-UHFFFAOYSA-N 0.000 description 1
- 241001144416 Picornavirales Species 0.000 description 1
- 241000709664 Picornaviridae Species 0.000 description 1
- 241000711798 Rabies lyssavirus Species 0.000 description 1
- 101000931114 Rattus norvegicus Glucose-6-phosphate isomerase Proteins 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- FBPFZTCFMRRESA-NQAPHZHOSA-N Sorbitol Polymers OCC(O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-NQAPHZHOSA-N 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 150000001243 acetic acids Chemical class 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- 150000001559 benzoic acids Chemical class 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 210000000234 capsid Anatomy 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000008957 cocaer Nutrition 0.000 description 1
- ZPUCINDJVBIVPJ-LJISPDSOSA-N cocaine Chemical compound O([C@H]1C[C@@H]2CC[C@@H](N2C)[C@H]1C(=O)OC)C(=O)C1=CC=CC=C1 ZPUCINDJVBIVPJ-LJISPDSOSA-N 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000013256 coordination polymer Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 231100000676 disease causative agent Toxicity 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012894 fetal calf serum Substances 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 238000007646 gravure printing Methods 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229960002285 methylbenzethonium chloride Drugs 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002941 microtiter virus yield reduction assay Methods 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 239000007922 nasal spray Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 229960003531 phenolsulfonphthalein Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 238000012809 post-inoculation Methods 0.000 description 1
- UAJUXJSXCLUTNU-UHFFFAOYSA-N pranlukast Chemical compound C=1C=C(OCCCCC=2C=CC=CC=2)C=CC=1C(=O)NC(C=1)=CC=C(C(C=2)=O)C=1OC=2C=1N=NNN=1 UAJUXJSXCLUTNU-UHFFFAOYSA-N 0.000 description 1
- 229960004583 pranlukast Drugs 0.000 description 1
- 238000013138 pruning Methods 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28468881A | 1981-07-20 | 1981-07-20 | |
| US28468881 | 1981-07-20 | ||
| US39278182A | 1982-06-30 | 1982-06-30 | |
| US39278182 | 1982-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8202885A true NL8202885A (nl) | 1983-02-16 |
Family
ID=26962741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8202885A NL8202885A (nl) | 1981-07-20 | 1982-07-16 | Preparaten met een werking tegen virussen en methoden en produkten waarbij van dergelijke preparaten gebruik wordt gemaakt. |
Country Status (14)
| Country | Link |
|---|---|
| KR (1) | KR870002047B1 (ko) |
| AU (1) | AU554127B2 (ko) |
| CA (1) | CA1188225A (ko) |
| DE (1) | DE3227126C2 (ko) |
| DK (1) | DK315482A (ko) |
| FI (1) | FI822542L (ko) |
| FR (1) | FR2509577B1 (ko) |
| GB (1) | GB2103089B (ko) |
| GR (1) | GR76879B (ko) |
| IT (1) | IT1212049B (ko) |
| LU (1) | LU84282A1 (ko) |
| NL (1) | NL8202885A (ko) |
| PH (1) | PH21282A (ko) |
| SE (1) | SE8204372L (ko) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3229097A1 (de) * | 1982-08-04 | 1984-02-09 | Schülke & Mayr GmbH, 2000 Hamburg | Mikrobizide mittel |
| DE3333443A1 (de) * | 1983-09-16 | 1985-03-28 | B. Braun Melsungen Ag, 3508 Melsungen | Desinfektionsmittel-konzentrate auf der basis von kurzkettigen fettsaeuren |
| US4719235A (en) * | 1984-10-16 | 1988-01-12 | Gerald N. Kern | Methods and compositions for treating viral infection |
| US4738847A (en) * | 1985-01-14 | 1988-04-19 | Kimberly-Clark Corporation | Multi-ply virucidal product |
| US4885310A (en) * | 1985-05-09 | 1989-12-05 | Gerald N. Kern | Anti-fungal methods and agent |
| US4752617A (en) * | 1985-06-05 | 1988-06-21 | Gerald N. Kern | Anti-bacterial methods and agents |
| US4717737A (en) * | 1985-06-05 | 1988-01-05 | Gerald N. Kern | Anti-bacterial methods and agent |
| IT1213453B (it) * | 1985-08-02 | 1989-12-20 | Merz & Co Gmbh & Co | Composizione farmaceutica. |
| US4615937A (en) * | 1985-09-05 | 1986-10-07 | The James River Corporation | Antimicrobially active, non-woven web used in a wet wiper |
| US4737405A (en) * | 1985-09-30 | 1988-04-12 | James River Corporation | Binder catalyst for an antimicrobially active, non-woven web |
| US4740398A (en) * | 1985-09-30 | 1988-04-26 | James River Corporation | Binder catalyst for an antimicrobially active, non-woven web |
| DE3622089A1 (de) * | 1986-07-02 | 1988-01-07 | Krueger Gmbh & Co Kg | Viruzides mittel mit breitbandwirkung |
| US4732797A (en) * | 1987-02-27 | 1988-03-22 | James River Corporation | Wet wiper natural acid preservation system |
| US4997851A (en) * | 1987-12-31 | 1991-03-05 | Isaacs Charles E | Antiviral and antibacterial activity of fatty acids and monoglycerides |
| DK311489A (da) * | 1989-06-23 | 1990-12-24 | John Ejnar Andersen | Metode til at bekaempe virus-svampe og bakteriesygdomme hos mennesker og dyr |
| US5244922A (en) * | 1990-09-04 | 1993-09-14 | Burzynski Stanislaw R | Methods for treating viral infections |
| DE4031664A1 (de) * | 1990-10-05 | 1992-04-09 | Heimo Wessollek | Mittel zur verringerung des bakterienwachstums in wasser |
| US5489433A (en) * | 1991-01-04 | 1996-02-06 | Safe-Tee Chemical Products Company | Environmentally safe insecticide |
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| CH323778A (de) * | 1953-05-21 | 1957-08-15 | Schuelke & Mayr Gmbh | Desinfektionsmittel |
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| EP0049354A3 (en) * | 1980-09-08 | 1983-02-23 | Sterling Drug Inc. | Composition for therapeutic virucidal use, and articles and packages containing said composition |
| JPS5817167B2 (ja) * | 1980-11-10 | 1983-04-05 | 持田製薬株式会社 | 抗ウイルス作用を有する医薬組成物 |
-
1982
- 1982-07-14 DK DK315482A patent/DK315482A/da not_active Application Discontinuation
- 1982-07-15 CA CA000407348A patent/CA1188225A/en not_active Expired
- 1982-07-16 IT IT8248833A patent/IT1212049B/it active
- 1982-07-16 NL NL8202885A patent/NL8202885A/nl not_active Application Discontinuation
- 1982-07-19 FI FI822542A patent/FI822542L/fi not_active Application Discontinuation
- 1982-07-19 KR KR828203196A patent/KR870002047B1/ko active
- 1982-07-19 GR GR68791A patent/GR76879B/el unknown
- 1982-07-19 SE SE8204372A patent/SE8204372L/ unknown
- 1982-07-19 PH PH27588A patent/PH21282A/en unknown
- 1982-07-20 LU LU84282A patent/LU84282A1/fr unknown
- 1982-07-20 FR FR8212634A patent/FR2509577B1/fr not_active Expired
- 1982-07-20 AU AU86210/82A patent/AU554127B2/en not_active Ceased
- 1982-07-20 DE DE3227126A patent/DE3227126C2/de not_active Revoked
- 1982-07-20 GB GB08220966A patent/GB2103089B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3227126C2 (de) | 1993-11-18 |
| CA1188225A (en) | 1985-06-04 |
| SE8204372L (sv) | 1983-01-21 |
| DK315482A (da) | 1983-01-21 |
| KR840000243A (ko) | 1984-02-18 |
| LU84282A1 (fr) | 1983-02-07 |
| FI822542A0 (fi) | 1982-07-19 |
| GB2103089A (en) | 1983-02-16 |
| AU8621082A (en) | 1983-01-27 |
| KR870002047B1 (ko) | 1987-12-03 |
| FR2509577A1 (fr) | 1983-01-21 |
| IT1212049B (it) | 1989-11-08 |
| FR2509577B1 (fr) | 1988-06-03 |
| DE3227126A1 (de) | 1983-02-03 |
| GR76879B (ko) | 1984-09-04 |
| AU554127B2 (en) | 1986-08-07 |
| IT8248833A0 (it) | 1982-07-16 |
| FI822542L (fi) | 1983-01-21 |
| GB2103089B (en) | 1986-03-12 |
| SE8204372D0 (sv) | 1982-07-19 |
| PH21282A (en) | 1987-09-28 |
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