NL8003767A - Op het centrale zenuwstelsel werkende tripeptideamiden en werkwijze voor de vervaardiging daarvan. - Google Patents

Op het centrale zenuwstelsel werkende tripeptideamiden en werkwijze voor de vervaardiging daarvan. Download PDF

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Publication number
NL8003767A
NL8003767A NL8003767A NL8003767A NL8003767A NL 8003767 A NL8003767 A NL 8003767A NL 8003767 A NL8003767 A NL 8003767A NL 8003767 A NL8003767 A NL 8003767A NL 8003767 A NL8003767 A NL 8003767A
Authority
NL
Netherlands
Prior art keywords
group
solution
mmol
pyroglutamyl
dissolved
Prior art date
Application number
NL8003767A
Other languages
English (en)
Dutch (nl)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NL8003767A publication Critical patent/NL8003767A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NL8003767A 1979-06-28 1980-06-27 Op het centrale zenuwstelsel werkende tripeptideamiden en werkwijze voor de vervaardiging daarvan. NL8003767A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HURI000717 1979-06-28
HU79RI717A HU180925B (en) 1979-06-28 1979-06-28 Process for producing tripeptide-amides trh-analogues,effectives on the central nerve systhem

Publications (1)

Publication Number Publication Date
NL8003767A true NL8003767A (nl) 1980-12-30

Family

ID=11001100

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8003767A NL8003767A (nl) 1979-06-28 1980-06-27 Op het centrale zenuwstelsel werkende tripeptideamiden en werkwijze voor de vervaardiging daarvan.

Country Status (21)

Country Link
US (1) US4299821A (fi)
JP (1) JPS5636442A (fi)
AT (1) AT373578B (fi)
AU (1) AU538100B2 (fi)
BE (1) BE884014A (fi)
CA (1) CA1151154A (fi)
CH (1) CH650518A5 (fi)
CS (1) CS239907B2 (fi)
DD (1) DD151746A5 (fi)
DE (1) DE3024313A1 (fi)
DK (1) DK149611C (fi)
FI (1) FI74473C (fi)
FR (1) FR2460292A1 (fi)
GB (1) GB2058080B (fi)
HU (1) HU180925B (fi)
IL (1) IL60407A (fi)
IT (1) IT1150023B (fi)
NL (1) NL8003767A (fi)
PL (1) PL127100B1 (fi)
SE (1) SE447261B (fi)
SU (1) SU963463A3 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533209B1 (fr) * 1982-09-22 1985-11-08 Centre Nat Rech Scient Lipopeptides, leur obtention et leur application comme emulsifiants
NZ214543A (en) * 1984-12-14 1990-03-27 Australian Commercial Research Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle)
IT1186733B (it) * 1985-06-05 1987-12-16 Eniricerche Spa Composti tripeptidici ad azione ipotensiva
FR2597100A1 (fr) * 1986-01-21 1987-10-16 Nippon Shinyaku Co Ltd Derives du pyroglutamide
US5494919A (en) * 1993-11-09 1996-02-27 Merck & Co., Inc. 2-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
CZ134296A3 (en) * 1993-11-09 1996-12-11 Merck & Co Inc Piperidine, pyrrolidine and hexahydro-1h-azepine derivatives, process of their preparation and pharmaceutical compositions containing thereof
FR2733995B1 (fr) * 1995-05-09 1997-07-25 Inst Nat Sante Rech Med Inhibiteurs de l'inactivation de neuropeptides endogenes notamment la cholecystokinine, leurs procedes de preparation leur utilisation comme medicaments et procede de criblage de medicaments
DE19527575A1 (de) * 1995-07-28 1997-01-30 Basf Ag Verfahren zur Herstellung von peptidischer Wirkstoffe
US20020151502A1 (en) * 1997-10-09 2002-10-17 Albert Sattin Tri-peptides for neurological and neurobehavior applications
US20050233973A1 (en) * 1997-10-09 2005-10-20 Albert Sattin Tri-peptides for antidepressant applications
US7462595B2 (en) * 2004-09-17 2008-12-09 Prange Jr Arthur Jergen Methods for treating cancer-related fatigue

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959248A (en) * 1974-04-03 1976-05-25 Merck & Co., Inc. Analogs of thyrotropin-releasing hormone
LU73294A1 (fi) * 1975-09-02 1977-05-11

Also Published As

Publication number Publication date
AU538100B2 (en) 1984-07-26
GB2058080B (en) 1983-02-23
IT8023096A0 (it) 1980-06-26
DK149611C (da) 1987-01-26
PL225268A1 (fi) 1981-10-16
DE3024313A1 (de) 1981-01-29
HU180925B (en) 1983-05-30
FR2460292B1 (fi) 1983-11-18
GB2058080A (en) 1981-04-08
FI74473B (fi) 1987-10-30
DK274680A (da) 1980-12-29
ATA334680A (de) 1983-06-15
CS239907B2 (en) 1986-01-16
US4299821A (en) 1981-11-10
IT1150023B (it) 1986-12-10
PL127100B1 (en) 1983-09-30
SE447261B (sv) 1986-11-03
JPS5636442A (en) 1981-04-09
DK149611B (da) 1986-08-11
FI74473C (fi) 1988-02-08
CS458480A2 (en) 1985-05-15
AT373578B (de) 1984-02-10
FI802057A (fi) 1980-12-29
FR2460292A1 (fr) 1981-01-23
IL60407A0 (en) 1980-09-16
SE8004744L (sv) 1980-12-29
CH650518A5 (de) 1985-07-31
DE3024313C2 (fi) 1991-05-29
SU963463A3 (ru) 1982-09-30
DD151746A5 (de) 1981-11-04
AU5971980A (en) 1981-01-08
BE884014A (fr) 1980-12-29
CA1151154A (en) 1983-08-02
IL60407A (en) 1984-11-30

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed