NZ214543A - Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle) - Google Patents

Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle)

Info

Publication number
NZ214543A
NZ214543A NZ214543A NZ21454385A NZ214543A NZ 214543 A NZ214543 A NZ 214543A NZ 214543 A NZ214543 A NZ 214543A NZ 21454385 A NZ21454385 A NZ 21454385A NZ 214543 A NZ214543 A NZ 214543A
Authority
NZ
New Zealand
Prior art keywords
hle
amino acid
peptide derivatives
inhibit human
elastase enzyme
Prior art date
Application number
NZ214543A
Inventor
Bela Ternai
Original Assignee
Australian Commercial Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Australian Commercial Research filed Critical Australian Commercial Research
Publication of NZ214543A publication Critical patent/NZ214543A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NZ214543A 1984-12-14 1985-12-13 Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle) NZ214543A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPG857484 1984-12-14

Publications (1)

Publication Number Publication Date
NZ214543A true NZ214543A (en) 1990-03-27

Family

ID=3770882

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ214543A NZ214543A (en) 1984-12-14 1985-12-13 Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle)

Country Status (5)

Country Link
EP (1) EP0204775A4 (en)
JP (1) JPS62501147A (en)
AU (1) AU583578B2 (en)
NZ (1) NZ214543A (en)
WO (1) WO1986003746A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2217319A (en) * 1988-04-19 1989-10-25 Synpharm Ltd Racemic and optically active fatty amino acids, their homo- abd hetero-oligomers and conjugates, the process of their production, their pharmaceutical composi
WO1990005141A1 (en) * 1988-11-10 1990-05-17 Australian Commercial Research & Development Limited Amino acid and peptide inhibitors of human leukocytic elastase and collagenase
MX9301789A (en) * 1992-04-03 1993-10-01 Iaf Biochem Int NEW LIPOPHILIC OLIGOPEPTIDES WITH IMMUNOMODULATING ACTIVITY.
FR2719584B1 (en) * 1994-05-09 1996-06-07 Oreal New serine derivatives, their preparation and their use in cosmetic or dermatological compositions.

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH490338A (en) * 1967-04-13 1970-05-15 Ciba Geigy Process for the production of ACTH-active peptides with extended action
FR1591598A (en) * 1967-07-31 1970-05-04
US3574747A (en) * 1968-03-29 1971-04-13 Norwich Pharma Co Amides of diaminoacids
US3862928A (en) * 1969-07-09 1975-01-28 Akzona Inc Psychopharmacological hexa-peptides containing a d-phenylalanyl residue
CH552567A (en) * 1970-10-30 1974-08-15 Hoffmann La Roche PROCESS FOR PRODUCING PHENYLALANINE DERIVATIVES.
NL175293C (en) * 1972-02-08 1984-10-16 Akzo Nv METHOD FOR PREPARING OR MANUFACTURING A PHARMACEUTICAL PREPARATION WITH A PSYCHOPHARMACOLOGICAL ACTION, AND A METHOD FOR PREPARING A VASOPRESSIN DERIVED PEPTIDE.
BE795788A (en) * 1972-02-22 1973-08-22 Akzo Nv PROCESS FOR THE PREPARATION OF PEPTIDES AND PEPTIDE DERIVATIVES AND THEIR USE
NL175988C (en) * 1972-05-24 1985-02-01 Akzo Nv PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION WITH A PSYCHOPHARMACOLOGICAL EFFECT, THAT A PEPTIDE OR PEPTIDE DERIVATIVE DERIVED FROM AN AMINO ACIDS 4-10, FRAGMENT OF ADRENOCORTICOTROP HORMONE, AS AN PROPERTY, AND ITS PROPERTY, PROPERTY, AND ITS PROPERTY.
NL175618C (en) * 1972-07-15 1984-12-03 Akzo Nv PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL PREPARATION WITH A PSYCHOPHARMACOLOGICAL ACTION CONTAINING A PEPTIDE OR PEPTIDE DERIVATIVE AND A PROCESS FOR THE PREPARATION OF SUCH PEPTIDES.
CA1103239A (en) * 1976-03-23 1981-06-16 Charles E. Frohman Product and process for treating schizophrenia
PH14141A (en) * 1976-06-25 1981-03-05 Hoffmann La Roche Pharmaceutical composition containing dipeptide derivatives
FR2442241A2 (en) * 1978-03-20 1980-06-20 Anvar NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
WO1980000252A1 (en) * 1978-07-18 1980-02-21 Kabi Ab Bradykinin-inhibiting tripeptide derivatives
US4231782A (en) * 1978-11-03 1980-11-04 Monsanto Company N-Carbobenzoxy-N-phosphonomethylglycine thioesters
EP0013856B1 (en) * 1978-12-22 1983-03-09 ANVAR Agence Nationale de Valorisation de la Recherche New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds
HU180925B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for producing tripeptide-amides trh-analogues,effectives on the central nerve systhem
NL8005121A (en) * 1979-09-20 1981-03-24 Erba Farmitalia ORGANICALLY ACTIVE PEPTIDES.
DE2938420A1 (en) * 1979-09-22 1981-04-09 Hoechst Ag, 6000 Frankfurt NEW PEPTIDES AND METHOD FOR THEIR PRODUCTION
CS226907B1 (en) * 1981-08-07 1984-04-16 Kasafirek Evzen Alkylamides of carboxyalkanoylpeptides
FR2533209B1 (en) * 1982-09-22 1985-11-08 Centre Nat Rech Scient LIPOPEPTIDES, THEIR OBTAINMENT AND THEIR APPLICATION AS EMULSIFIERS
EP0136879A3 (en) * 1983-09-30 1987-01-07 Yamanouchi Pharmaceutical Co., Ltd. Fatty acid derivatives and processes of producing them
CA1341029C (en) * 1985-02-04 2000-06-20 Michael Kolb Peptidase inhibitors
JPH0510569A (en) * 1991-07-05 1993-01-19 Kubota Corp Air conditioner

Also Published As

Publication number Publication date
AU5208386A (en) 1986-07-22
WO1986003746A1 (en) 1986-07-03
JPS62501147A (en) 1987-05-07
EP0204775A4 (en) 1989-10-04
AU583578B2 (en) 1989-05-04
EP0204775A1 (en) 1986-12-17

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