NL7920016A - Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen. - Google Patents

Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen. Download PDF

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Publication number
NL7920016A
NL7920016A NL7920016A NL7920016A NL7920016A NL 7920016 A NL7920016 A NL 7920016A NL 7920016 A NL7920016 A NL 7920016A NL 7920016 A NL7920016 A NL 7920016A NL 7920016 A NL7920016 A NL 7920016A
Authority
NL
Netherlands
Prior art keywords
hydroxy
fluorine
vitamin
compounds
acyl
Prior art date
Application number
NL7920016A
Other languages
English (en)
Dutch (nl)
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NL7920016A publication Critical patent/NL7920016A/nl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7920016A 1978-07-26 1979-07-24 Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen. NL7920016A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92827978 1978-07-26
US05/928,279 US4188345A (en) 1978-07-26 1978-07-26 Fluorovitamin D compounds and processes for their preparation

Publications (1)

Publication Number Publication Date
NL7920016A true NL7920016A (nl) 1980-05-30

Family

ID=25456012

Family Applications (2)

Application Number Title Priority Date Filing Date
NL7920012A NL7920012A (nl) 1978-07-26 1979-07-24 Werkwijze ter bereiding van 1-gefluoreerde vitamine d verbindingen.
NL7920016A NL7920016A (nl) 1978-07-26 1979-07-24 Werkwijze ter bereiding van in de zijketen gefluoreerde vitamine d verbindingen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL7920012A NL7920012A (nl) 1978-07-26 1979-07-24 Werkwijze ter bereiding van 1-gefluoreerde vitamine d verbindingen.

Country Status (14)

Country Link
US (1) US4188345A (sv)
JP (2) JPS6312867B2 (sv)
AU (1) AU521131B2 (sv)
BE (1) BE877918A (sv)
CH (2) CH650237A5 (sv)
DK (2) DK156716C (sv)
FR (1) FR2433514B1 (sv)
GB (1) GB2026494B (sv)
IE (1) IE48463B1 (sv)
IL (1) IL57801A (sv)
NL (2) NL7920012A (sv)
NZ (1) NZ190939A (sv)
SE (2) SE8001746L (sv)
WO (2) WO1980000338A1 (sv)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4410515A (en) * 1981-04-01 1983-10-18 Massachusetts General Hospital Vitamin D glycosides and a method of use
WO1984000107A1 (en) * 1982-06-30 1984-01-19 Massachusetts Gen Hospital Vitamin d glycosides
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
US4448721A (en) * 1982-09-20 1984-05-15 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 compounds and process for preparing same
GB2145091B (en) * 1983-08-18 1987-08-12 Wisconsin Alumni Res Found Vitamin d3 derivatives
US4661294A (en) * 1985-03-18 1987-04-28 The General Hospital Corporation Biologically active 1-thio derivatives of vitamin D
US5401731A (en) * 1989-06-29 1995-03-28 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Productionsaktieselskab) Vitamin D analogues
TR25295A (tr) * 1992-02-26 1993-01-01 Simfer Dayanikli Tueketim Mamu Kati yakit yakan sobalar icin yanma havasi ön isitma sistemi
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
EP1021401A1 (en) * 1995-09-21 2000-07-26 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US6100294A (en) 1997-05-16 2000-08-08 Women And Infants Hospital Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof
MX2008012114A (es) * 2006-04-06 2009-03-06 Wisconsin Alumni Res Found Analogos 19-nor-vitamina d con anillo 1,2, o 3,2 heterociclico.
JP2009532458A (ja) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１α−ヒドロキシ−１９，２１−ジノルビタミンＤ３類縁体およびその使用
WO2007118198A2 (en) * 2006-04-06 2007-10-18 Wisconsin Alumni Research Foundation 2-METHYLENE-1α,25-DIHYDROXY-19,21-DINORVITAMIN D3 ANALOGS AND USES THEREOF
NZ570711A (en) 2006-04-06 2012-10-26 Wisconsin Alumni Res Found 2-Substituted-1alpha, 25-dihydroxy-19,26,27-trinor vitamin D analogs and uses thereof
JP2009532457A (ja) * 2006-04-06 2009-09-10 ウイスコンシン アラムニ リサーチ ファンデーション ２−メチレン−１α−ヒドロキシ−１８，１９，２１−トリノルビタミンＤ３類縁体およびその使用
US7704981B2 (en) * 2006-04-06 2010-04-27 Wisconsin Alumni Research Foundation 2-methylene-1alpha,25-dihydroxy-18,19,21-trinorvitamin D3 and uses thereof
MX2008012674A (es) * 2006-04-10 2008-10-15 Wisconsin Alumni Res Found Compuestos de 1 a-hidroxi-2-(3'-hidroxipropiliden)-19-nor-vitamina d con una cadena lateral 1,1-dimetilpropilo.
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
US8814007B2 (en) 2010-12-31 2014-08-26 Medline Industries, Inc. Dispenser with directional flow controlling flange and corresponding systems

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives

Also Published As

Publication number Publication date
CH641445A5 (de) 1984-02-29
FR2433514A1 (fr) 1980-03-14
JPS6312867B2 (sv) 1988-03-23
GB2026494A (en) 1980-02-06
JPS55500428A (sv) 1980-07-17
NZ190939A (en) 1982-09-07
AU4920679A (en) 1980-01-31
JPS6312868B2 (sv) 1988-03-23
IE48463B1 (en) 1985-01-23
US4188345A (en) 1980-02-12
BE877918A (fr) 1979-11-16
GB2026494B (en) 1982-12-15
SE8001746L (sv) 1980-03-05
IL57801A0 (en) 1979-11-30
WO1980000339A1 (en) 1980-03-06
DK156716C (da) 1990-02-19
IL57801A (en) 1984-03-30
DK127580A (da) 1980-03-25
DK127480A (da) 1980-03-25
CH650237A5 (de) 1985-07-15
DK156716B (da) 1989-09-25
NL7920012A (nl) 1980-05-30
JPS55500430A (sv) 1980-07-17
DK154211C (da) 1989-03-13
DK154211B (da) 1988-10-24
SE8001747L (sv) 1980-03-05
FR2433514B1 (fr) 1986-05-23
IE791496L (en) 1980-01-26
AU521131B2 (en) 1982-03-18
WO1980000338A1 (en) 1980-03-06

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