NL7409321A - Nieuwe derivaten van 2-benzamido-5-nitro-thia- - Google Patents

Nieuwe derivaten van 2-benzamido-5-nitro-thia-

Info

Publication number
NL7409321A
NL7409321A NL7409321A NL7409321A NL7409321A NL 7409321 A NL7409321 A NL 7409321A NL 7409321 A NL7409321 A NL 7409321A NL 7409321 A NL7409321 A NL 7409321A NL 7409321 A NL7409321 A NL 7409321A
Authority
NL
Netherlands
Prior art keywords
benzamido
thia
nitro
new derivatives
derivatives
Prior art date
Application number
NL7409321A
Other languages
English (en)
Other versions
NL176779B (nl
NL176779C (nl
Original Assignee
Phavic Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phavic Sprl filed Critical Phavic Sprl
Publication of NL7409321A publication Critical patent/NL7409321A/nl
Publication of NL176779B publication Critical patent/NL176779B/nl
Application granted granted Critical
Publication of NL176779C publication Critical patent/NL176779C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/58—Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NLAANVRAGE7409321,A 1973-08-08 1974-07-10 Werkwijze voor het bereiden of vervaardigen van een preparaat voor het bestrijden van parasieten en werkwijze voor het bereiden van een 2-benzamido-5-nitrothiazoolderivaat met parasietenbestrijdende werking. NL176779C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3760873A GB1437800A (en) 1973-08-08 1973-08-08 Derivatives of 2-benzamido-5-nitro-thiazoles

Publications (3)

Publication Number Publication Date
NL7409321A true NL7409321A (nl) 1975-02-11
NL176779B NL176779B (nl) 1985-01-02
NL176779C NL176779C (nl) 1985-06-03

Family

ID=10397712

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7409321,A NL176779C (nl) 1973-08-08 1974-07-10 Werkwijze voor het bereiden of vervaardigen van een preparaat voor het bestrijden van parasieten en werkwijze voor het bereiden van een 2-benzamido-5-nitrothiazoolderivaat met parasietenbestrijdende werking.

Country Status (14)

Country Link
US (1) US3950351A (nl)
JP (1) JPS5041858A (nl)
AR (1) AR201880A1 (nl)
BE (1) BE817878A (nl)
CA (1) CA1041519A (nl)
CH (1) CH583215A5 (nl)
DE (1) DE2438037C2 (nl)
ES (1) ES428906A1 (nl)
FR (1) FR2240010B1 (nl)
GB (1) GB1437800A (nl)
IL (1) IL45194A (nl)
NL (1) NL176779C (nl)
OA (1) OA04761A (nl)
ZA (1) ZA744409B (nl)

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FR2435905A1 (fr) * 1978-09-13 1980-04-11 Anvar Nouveaux agents molluscicides derives du benzamido-2 nitro-5 thiazole
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
AR226579A1 (es) * 1979-12-21 1982-07-30 Wellcome Found Metodo para la preparacion de un compuesto de 2-benzoilimino-5-nitro-4-tiazolin-3-acetamida
SK281949B6 (sk) * 1994-04-13 2001-09-11 Jean-Francois Rossignol Derivát benzamidu, farmaceutický prostriedok, ktorý ho obsahuje, a použitie
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen
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US7125568B2 (en) * 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
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US20060194853A1 (en) * 2004-10-08 2006-08-31 Rossignol Jean F Alkyl benzamides
GB0423044D0 (en) * 2004-10-16 2004-11-17 Astrazeneca Ab Compounds
US7700640B2 (en) 2004-10-16 2010-04-20 Astrazeneca Ab Process for making phenoxy benzamide compounds
GB0423043D0 (en) * 2004-10-16 2004-11-17 Astrazeneca Ab Compounds
US20070015803A1 (en) * 2005-04-12 2007-01-18 Romark Laboratories L.C. Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents
US20110059941A1 (en) * 2005-05-24 2011-03-10 Peter William Rodney Caulkett 2-phenyl substituted imidazol [4,5b] pyridine/pyrazine and purine derivatives as glucokinase modulators
TW200714597A (en) * 2005-05-27 2007-04-16 Astrazeneca Ab Chemical compounds
NZ575513A (en) * 2005-07-09 2009-11-27 Astrazeneca Ab Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes
EP2027113A1 (en) * 2005-07-09 2009-02-25 AstraZeneca AB Heteroaryl benzamide derivatives for use as glk activators in the treatment of diabetes
US20110053910A1 (en) * 2005-07-09 2011-03-03 Mckerrecher Darren 2 -heterocyclyloxybenzoyl amino heterocyclyl compounds as modulators of glucokinase for the treatment of type 2 diabetes
US9202182B2 (en) * 2005-08-11 2015-12-01 International Business Machines Corporation Method and system for analyzing business architecture
TW200738621A (en) * 2005-11-28 2007-10-16 Astrazeneca Ab Chemical process
MX2008008723A (es) * 2006-01-09 2008-09-26 Romark Lab Lc Tratamiento de la hepatitis viral.
WO2008008480A2 (en) * 2006-07-12 2008-01-17 Cumbre Pharmaceuticals Inc. Nitroheteroaryl-containing rifamycin derivatives
CN100465169C (zh) * 2006-08-02 2009-03-04 杭州欣阳三友精细化工有限公司 硝唑尼特的制备方法
TW200825063A (en) * 2006-10-23 2008-06-16 Astrazeneca Ab Chemical compounds
CL2007003061A1 (es) * 2006-10-26 2008-08-01 Astrazeneca Ab Compuestos derivados de 3,5-dioxi-benzamida; proceso de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una enfermedad mediada a traves de glk, tal como la diabetes tipo 2.
KR20090090390A (ko) * 2006-12-21 2009-08-25 아스트라제네카 아베 Ｇｌｋ 활성제로서 유용한 신규 결정 화합물
CN101007792B (zh) * 2007-01-31 2010-05-26 浙江大学 一种合成硝基噻唑苯酰胺化合物的方法
JP5676258B2 (ja) 2007-08-03 2015-02-25 ロマーク ラボラトリース，エル．シー． アルキルスルホニル置換チアゾリド化合物
AU2009278929B2 (en) * 2008-08-04 2012-07-05 Astrazeneca Ab Pyrazolo [3,4] pyrimidin-4-yl derivatives and their uses to treat diabetes and obesity
UY32306A (es) 2008-12-09 2010-07-30 Gilead Sciences Inc Derivados de pteridinona y pirimidinodiazepinona y composiciones farmacéuticas que modulan en forma selectiva los receptores tipo toll, métodos y usos
GB0902406D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Crystalline polymorphic form
US8524278B2 (en) 2009-02-13 2013-09-03 Romark Laboratories L.C. Controlled release pharmaceutical formulations of nitazoxanide
GB0902434D0 (en) * 2009-02-13 2009-04-01 Astrazeneca Ab Chemical process
WO2010116177A1 (en) 2009-04-09 2010-10-14 Astrazeneca Ab A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity
WO2010116176A1 (en) * 2009-04-09 2010-10-14 Astrazeneca Ab Pyrazolo [4, 5-e] pyrimidine derivative and its use to treat diabetes and obesity
JP5918124B2 (ja) 2009-05-12 2016-05-18 ロマーク ラボラトリーズ エル．シー． ハロアルキルヘテロアリールベンズアミド化合物
MX341877B (es) 2009-06-26 2016-09-06 Romark Laboratories L C * Compuestos y métodos para tratar influenza.
CN101602744B (zh) * 2009-06-30 2011-06-01 青岛康地恩药业有限公司 一种硝唑尼特的制备方法
WO2013110975A1 (es) 2012-01-27 2013-08-01 Siegfried Rhein S.A. De C.V. Composición de nitazoxanida mejorada y proceso para prepararla
WO2014049397A1 (es) 2012-09-27 2014-04-03 Siegfried Rhein S.A. De C.V. Composición sinérgica de nitazoxanida y mebendazol, procesos para prepararla y el uso de dicha composición para el tratamiento de la parasitosis humana
EP3010345A4 (en) * 2013-06-21 2017-04-12 The Regents of The University of California Expanded therapeutic potential in nitroheteroaryl antimicrobials
TWI806081B (zh) 2014-07-11 2023-06-21 美商基利科學股份有限公司 用於治療HIV之toll樣受體調節劑
PT3194401T (pt) 2014-09-16 2020-12-23 Gilead Sciences Inc Formas sólidas de modulador de recetor tipo toll
JP6633092B2 (ja) 2014-11-11 2020-01-22 ロマーク ラボラトリーズ，リミティド カンパニー チゾキサニド、その類似体又は塩のプロドラッグを用いる組成物及び治療方法
CN105175352A (zh) * 2015-10-27 2015-12-23 杭州澳医保灵药业有限公司 一种硝唑尼特的制备方法
CN106831640A (zh) * 2015-12-03 2017-06-13 江苏正大丰海制药有限公司 一种硝唑尼特晶体的制备方法
PT3436074T (pt) 2016-03-31 2020-08-21 Romark Laboratories Lc Compostos tiazolida para tratamento de infeções virais
SI3442580T1 (sl) 2016-04-11 2021-01-29 Genfit Metode zdravljenja holestatičnih in fibrotičnih bolezni
JP7224294B2 (ja) 2017-01-27 2023-02-17 ジェンフィ 組合せ療法のための医薬組成物
US11173149B2 (en) 2017-04-18 2021-11-16 Romark Laboratories L.C. Inhibition of protein disulfide-isomerase A3
CA3130518A1 (en) 2019-04-12 2020-10-15 Nicolas STANKOVIC-VALENTIN Nitazoxanide and thiazolides for use in the treatment of diseases associated with oxidative stress
CA3153784A1 (en) 2019-10-28 2021-05-06 Nicolas STANKOVIC-VALENTIN Combination therapy of elafibranor and nitazoxanide having antioxident properties
WO2022020243A1 (en) 2020-07-20 2022-01-27 Romark Laboratories L.C. Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine
AU2021333566A1 (en) 2020-08-24 2023-03-16 Romark Laboratories L.C. Use of thiazolides against coronaviruses
CN114044761B (zh) * 2021-02-24 2022-05-17 成都贝诺科成生物科技有限公司 一种新的硝基噻唑衍生物及其应用
WO2022218239A1 (zh) * 2021-04-12 2022-10-20 杜心赟 新型噻唑类化合物及其制备方法和用途
CN116898846A (zh) * 2022-04-12 2023-10-20 成都贝诺科成生物科技有限公司 一种硝基噻唑衍生物在制备抑制幽门螺杆菌的抑菌剂中的用途

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Publication number Priority date Publication date Assignee Title
CA497537A (en) * 1953-11-10 H. Clark Joe 2-substituted amino-5-nitrothiazoles
US2829084A (en) * 1958-04-01 Certain alkyl-n
US2735798A (en) * 1956-02-21 Acyl amevo-nitrothiazole compositions
US2401522A (en) * 1942-04-17 1946-06-04 Firm Sandoz Ltd Aromatic carboxylic acid amides and a process for their manufacture
GB577418A (en) * 1942-04-17 1946-05-17 Sandoz Ltd Process for the preparation of amides of aromatic carboxylic acids
FR1306603A (fr) * 1958-08-14 1962-10-19 Innothera Lab Sa Dérivés thiazoliques et leur procédé de préparation
US3475446A (en) * 1967-06-27 1969-10-28 Parke Davis & Co N-(5-nitro-2-thiazolyl)-cycloalkanecarboxamides

Also Published As

Publication number Publication date
US3950351A (en) 1976-04-13
GB1437800A (en) 1976-06-03
BE817878A (fr) 1975-01-20
NL176779B (nl) 1985-01-02
CH583215A5 (nl) 1976-12-31
DE2438037A1 (de) 1975-02-20
IL45194A (en) 1977-10-31
AR201880A1 (es) 1975-04-24
IL45194A0 (en) 1974-10-22
AU7135574A (en) 1976-01-22
FR2240010A1 (nl) 1975-03-07
FR2240010B1 (nl) 1978-03-24
OA04761A (fr) 1980-08-31
CA1041519A (en) 1978-10-31
ES428906A1 (es) 1976-08-16
NL176779C (nl) 1985-06-03
DE2438037C2 (de) 1982-06-09
ZA744409B (en) 1975-07-30
JPS5041858A (nl) 1975-04-16

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Legal Events

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BA A request for search or an international-type search has been filed
CNR Transfer of rights (patent application after its laying open for public inspection)

Free format text: JEAN-FRANCOIS ROSSIGNOL

BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee