|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
*
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
SI1874781T1
(sl)
*
|
2006-04-19 |
2009-12-31 |
Boehringer Ingelheim Int |
Dihidrotienopirimidini za zdravljenje vnetnih obolenj
|
|
CA2650295C
(en)
*
|
2006-04-26 |
2015-12-29 |
Genentech, Inc. |
Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
|
|
JP5546240B2
(ja)
|
2006-04-26 |
2014-07-09 |
ジェネンテック， インコーポレイテッド |
医薬化合物
|
|
BRPI0710874A2
(pt)
|
2006-04-26 |
2012-02-14 |
Hoffmann La Roche |
compostos de tienopirimidina, processos de produção dos referidos compostos, composições farmacêuticas contendo os mesmos, kit, produto, e usos dos compostos
|
|
CN101675053B
(zh)
*
|
2006-12-07 |
2014-03-12 |
健泰科生物技术公司 |
磷酸肌醇3-激酶抑制剂化合物及使用方法
|
|
TWI499420B
(zh)
*
|
2006-12-07 |
2015-09-11 |
Hoffmann La Roche |
肌醇磷脂３-激酶抑制劑化合物及使用方法
|
|
CN101932587A
(zh)
|
2007-09-24 |
2010-12-29 |
吉宁特有限公司 |
噻唑并嘧啶pi3k抑制剂化合物及使用方法
|
|
CN101827853A
(zh)
|
2007-10-19 |
2010-09-08 |
贝林格尔.英格海姆国际有限公司 |
杂环取代的哌嗪子基-二氢噻吩并嘧啶
|
|
US8486948B2
(en)
|
2007-10-19 |
2013-07-16 |
Boehringer Ingelheim International Gmbh |
Piperazinodihydrothienopyrimidine derivatives
|
|
ES2381452T3
(es)
*
|
2007-10-19 |
2012-05-28 |
Boehringer Ingelheim International Gmbh |
PIPERIDINO-DIHIDROTIENOPIRIMIDINAS sustituidas
|
|
ES2439705T3
(es)
|
2007-10-25 |
2014-01-24 |
Genentech, Inc. |
Proceso para la preparación de compuestos de tienopirimidina
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
BRPI1006189A2
(pt)
|
2009-03-12 |
2020-08-18 |
Genentech Inc |
uso de uma combinação terapêutica, formulação farmacêutica, artigo de manufatura, produto, método para determinar compostos a serem utilizados em combinação para o tratamento de uma malignidade hematopoiética e método para selecionar compostos a serem utilizados em combinação para o tratamento de câncer
|
|
WO2010136491A1
(en)
*
|
2009-05-27 |
2010-12-02 |
F. Hoffmann-La Roche Ag |
Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
SG175708A1
(en)
*
|
2009-05-27 |
2011-12-29 |
Genentech Inc |
Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
|
|
EP2488178B1
(en)
*
|
2009-10-12 |
2016-11-16 |
F.Hoffmann-La Roche Ag |
Combinations of a pi3k inhibitor and a mek inhibitor
|
|
CN103038643A
(zh)
|
2010-04-16 |
2013-04-10 |
基因泰克公司 |
作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
|
|
WO2012088254A1
(en)
|
2010-12-22 |
2012-06-28 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
EP2959014B1
(en)
|
2013-02-25 |
2019-11-13 |
Genentech, Inc. |
Methods and compositions for detecting and treating drug resistant akt mutant
|
|
CN113423711B
(zh)
*
|
2018-10-01 |
2024-03-15 |
建新公司 |
作为udp糖基转移酶抑制剂的噻吩并[3,2-b]吡啶衍生物及其使用方法
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|