|
GB1570494A
(en)
*
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
US5280026A
(en)
*
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
GB8912335D0
(en)
*
|
1989-05-30 |
1989-07-12 |
Smithkline Beckman Intercredit |
Compounds
|
|
US5098902A
(en)
*
|
1991-03-18 |
1992-03-24 |
Warner-Lambert Company |
Method of treating neurodegenerative diseases
|
|
US6187777B1
(en)
|
1998-02-06 |
2001-02-13 |
Amgen Inc. |
Compounds and methods which modulate feeding behavior and related diseases
|
|
US6608053B2
(en)
*
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
GB0423653D0
(en)
|
2004-10-25 |
2004-11-24 |
Piramed Ltd |
Pharmaceutical compounds
|
|
RS51163B
(sr)
*
|
2006-04-19 |
2010-10-31 |
Boehringer Ingelheim International Gmbh. |
Dihidrotienopirimidin za lečenje zapaljenskih bolesti
|
|
EP1847543A1
(de)
|
2006-04-19 |
2007-10-24 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen
|
|
TWI498332B
(zh)
*
|
2006-04-26 |
2015-09-01 |
Hoffmann La Roche |
作為pi3k抑制劑之嘧啶衍生物及相關製備方法、醫藥組合物、用途、套組及產物
|
|
TW200801012A
(en)
|
2006-04-26 |
2008-01-01 |
Piramed Ltd |
Phosphoinositide 3-kinase inhibitor compounds and methods of use
|
|
WO2007129161A2
(en)
*
|
2006-04-26 |
2007-11-15 |
F. Hoffmann-La Roche Ag |
Thieno [3, 2-d] pyrimidine derivative useful as pi3k inhibitor
|
|
MX2009005950A
(es)
|
2006-12-07 |
2009-10-12 |
Genentech Inc |
Compuestos inhibidores de fosfoinositido 3-quinasas y metodos de uso.
|
|
RU2470936C2
(ru)
*
|
2006-12-07 |
2012-12-27 |
Дженентек, Инк. |
Соединения-ингибиторы фосфоинозитид 3-киназы и способы применения
|
|
CA2704711C
(en)
|
2007-09-24 |
2016-07-05 |
Genentech, Inc. |
Thiazolopyrimidine p13k inhibitor compounds and methods of use
|
|
MX2010004026A
(es)
*
|
2007-10-19 |
2010-04-30 |
Boehringer Ingelheim Int |
Piperidino-dihidrotienopirimidinas sustituidas.
|
|
EP2205609B1
(de)
|
2007-10-19 |
2017-03-29 |
Boehringer Ingelheim International GmbH |
Heterocyclus-substituierte piperazino-dihydrothienopyrimidine
|
|
ATE537175T1
(de)
|
2007-10-19 |
2011-12-15 |
Boehringer Ingelheim Int |
Neue piperazino-dihydrothienopyrimidin-derivate
|
|
JP5348725B2
(ja)
*
|
2007-10-25 |
2013-11-20 |
ジェネンテック， インコーポレイテッド |
チエノピリミジン化合物の製造方法
|
|
GB0721095D0
(en)
*
|
2007-10-26 |
2007-12-05 |
Piramed Ltd |
Pharmaceutical compounds
|
|
JP5709766B2
(ja)
|
2009-03-12 |
2015-04-30 |
ジェネンテック， インコーポレイテッド |
造血器腫瘍の治療のためのホスホイノシチド３キナーゼ阻害剤化合物と化学療法剤の併用
|
|
BRPI1009022A2
(pt)
*
|
2009-05-27 |
2016-03-08 |
Hoffmann La Roche |
"composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"
|
|
US8158625B2
(en)
*
|
2009-05-27 |
2012-04-17 |
Genentech, Inc. |
Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
|
|
CA2776944A1
(en)
*
|
2009-10-12 |
2011-05-12 |
F. Hoffmann-La Roche Ag |
Combinations of a pi3k inhibitor and a mek inhibitor
|
|
WO2011130654A1
(en)
|
2010-04-16 |
2011-10-20 |
Genentech, Inc. |
Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
|
|
US20140004209A1
(en)
|
2010-12-22 |
2014-01-02 |
Genentech, Inc. |
Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
|
|
US20130059866A1
(en)
|
2011-08-24 |
2013-03-07 |
Boehringer Ingelheim International Gmbh |
Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
|
|
US9802954B2
(en)
|
2011-08-24 |
2017-10-31 |
Boehringer Ingelheim International Gmbh |
Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
|
|
EP2959014B1
(en)
|
2013-02-25 |
2019-11-13 |
Genentech, Inc. |
Methods and compositions for detecting and treating drug resistant akt mutant
|
|
EP3861000A1
(en)
*
|
2018-10-01 |
2021-08-11 |
Genzyme Corporation |
Thieno[3,2-b]pyridine derivatives as udp glycosyltransferase inhibitors and methods of use
|
|
GB202014736D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Imperial College Innovations Ltd |
Novel compounds and their use in therapy
|