FR2081464B1 - - Google Patents

Info

Publication number
FR2081464B1
FR2081464B1 FR7102796A FR7102796A FR2081464B1 FR 2081464 B1 FR2081464 B1 FR 2081464B1 FR 7102796 A FR7102796 A FR 7102796A FR 7102796 A FR7102796 A FR 7102796A FR 2081464 B1 FR2081464 B1 FR 2081464B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7102796A
Other versions
FR2081464A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of FR2081464A1 publication Critical patent/FR2081464A1/fr
Application granted granted Critical
Publication of FR2081464B1 publication Critical patent/FR2081464B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FR7102796A 1970-01-28 1971-01-28 Expired FR2081464B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung

Publications (2)

Publication Number Publication Date
FR2081464A1 FR2081464A1 (fr) 1971-12-03
FR2081464B1 true FR2081464B1 (fr) 1975-04-18

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7102796A Expired FR2081464B1 (fr) 1970-01-28 1971-01-28

Country Status (9)

Country Link
US (1) US3763156A (fr)
AU (1) AU2468871A (fr)
BE (1) BE762135A (fr)
ES (2) ES387553A1 (fr)
FR (1) FR2081464B1 (fr)
GB (1) GB1309182A (fr)
IL (1) IL36079A0 (fr)
NL (1) NL7101043A (fr)
NO (1) NO129205B (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
WO2006111549A1 (fr) * 2005-04-21 2006-10-26 Boehringer Ingelheim International Gmbh Dihydrothienopyrimidines destines au traitement de maladies inflammatoires
EP1847543A1 (fr) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines pour le traitement de maladies inflammatoires
DK2024372T3 (da) 2006-04-26 2010-09-20 Hoffmann La Roche Thieno[3,2-d]pyrimidin-derivat, der er egnet som P13K inhibitor
KR101402474B1 (ko) 2006-04-26 2014-06-19 제넨테크, 인크. 포스포이노시티드 3-키나제 억제제 화합물 및 이를 포함하는 약학적 조성물
JP5546240B2 (ja) 2006-04-26 2014-07-09 ジェネンテック， インコーポレイテッド 医薬化合物
MY180595A (en) * 2006-12-07 2020-12-03 Genentech Inc Phosphoinositide 3-kinase inhibitor compounds and methods of use
MX2009005925A (es) * 2006-12-07 2009-08-12 Genentech Inc Compuestos inhibidores de fosfoinositida 3-quinasa y los metodos de uso.
EP2207781B1 (fr) 2007-09-24 2012-11-28 Genentech, Inc. Composés inhibiteurs de la pi3k à base de thiazolopyrimidine et les procédés pour l'utilisation
WO2009050248A1 (fr) * 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh Pipéridino-dihydrothiénopyrimidines substituées
EP2205609B1 (fr) * 2007-10-19 2017-03-29 Boehringer Ingelheim International GmbH Composés pipérazino-dihydro-thiénopyrimidine substituées par un hétérocycle
CA2702518A1 (fr) 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh Nouveaux derives de piperazino-dihydrothienopyrimidine
WO2009055730A1 (fr) * 2007-10-25 2009-04-30 Genentech, Inc. Procédé de préparation de composés de thiénopyrimidine
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
WO2010105008A2 (fr) 2009-03-12 2010-09-16 Genentech, Inc. Combinaisons de composés inhibiteurs de phosphoinositide 3-kinase et d'agents chimiothérapeutiques pour le traitement de tumeurs malignes hématopoïétiques
CN102459272B (zh) 2009-05-27 2014-08-06 健泰科生物技术公司 对P110δ具有选择性的为PI3K抑制剂的二环嘧啶化合物和使用方法
WO2010136491A1 (fr) * 2009-05-27 2010-12-02 F. Hoffmann-La Roche Ag Composés bicycliques indole-pyrimidine inhibiteurs de pi3k sélectifs pour p110 delta et leurs procédés d'utilisation
WO2011054620A1 (fr) * 2009-10-12 2011-05-12 F. Hoffmann-La Roche Ag Combinaisons d'un inhibiteur de pi3k et d'un inhibiteur de mek
CA2793892A1 (fr) 2010-04-16 2011-10-20 Elizabeth Punnoose Foxo3a utilisee comme biomarqueur predictif pour l'efficacite d'un inhibiteur de la voie des kinases pi3k/akt
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
EP2959014B1 (fr) 2013-02-25 2019-11-13 Genentech, Inc. Procédés et compositions pour détecter et traiter un mutant d'akt résistant aux médicaments
WO2020072504A1 (fr) * 2018-10-01 2020-04-09 Genzyme Corporation Dérivés de thiéno[3,2-b]pyridine utilisés en tant qu'inhibiteurs de l'udp-glycosyltransférase et procédés d'utilisation
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
ES387553A1 (es) 1974-01-16
ES387554A1 (es) 1974-01-16
IL36079A0 (en) 1971-03-24
NO129205B (fr) 1974-03-11
US3763156A (en) 1973-10-02
GB1309182A (en) 1973-03-07
NL7101043A (fr) 1971-07-30
FR2081464A1 (fr) 1971-12-03
BE762135A (fr) 1971-07-27
AU2468871A (en) 1972-07-27

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Legal Events

Date Code Title Description
ST Notification of lapse