BE762135A - Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer - Google Patents

Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Info

Publication number
BE762135A
BE762135A BE762135A BE762135A BE762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A BE 762135 A BE762135 A BE 762135A
Authority
BE
Belgium
Prior art keywords
thieno
pyrimidines
morpholino
news
manufacturing
Prior art date
Application number
BE762135A
Other languages
English (en)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19702003714 external-priority patent/DE2003714C/de
Priority claimed from DE19702058086 external-priority patent/DE2058086A1/de
Priority claimed from DE19702058085 external-priority patent/DE2058085A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of BE762135A publication Critical patent/BE762135A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE762135A 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer BE762135A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19702003714 DE2003714C (de) 1970-01-28 2 Piperazino 4 morpholino thieno eckige Klammer auf 3,2 d eckige Klammer zu pyrimidin und dessen Saureadditions salze
DE19702058086 DE2058086A1 (de) 1970-11-26 1970-11-26 Neue 4-Morpholino-thieno[3,2-d]pyrimidine,deren Salze und Verfahren zur Herstellung
DE19702058085 DE2058085A1 (de) 1970-11-26 1970-11-26 Neues Verfahren zur Herstellung von 4-Morpholino-thieno[3,2-d]pyrimidinen

Publications (1)

Publication Number Publication Date
BE762135A true BE762135A (fr) 1971-07-27

Family

ID=27182372

Family Applications (1)

Application Number Title Priority Date Filing Date
BE762135A BE762135A (fr) 1970-01-28 1971-01-27 Nouvelles 4-morpholino-thieno-(3,2-d)pyrimidines et procede pour les fabriquer

Country Status (9)

Country Link
US (1) US3763156A (fr)
AU (1) AU2468871A (fr)
BE (1) BE762135A (fr)
ES (2) ES387554A1 (fr)
FR (1) FR2081464B1 (fr)
GB (1) GB1309182A (fr)
IL (1) IL36079A0 (fr)
NL (1) NL7101043A (fr)
NO (1) NO129205B (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
US5280026A (en) * 1989-05-30 1994-01-18 Smithkline Beecham Intercredit B.V. Thienopyrimidines
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
PL1874781T3 (pl) * 2006-04-19 2009-12-31 Boehringer Ingelheim Int Dihydrotienopirymidyny do leczenia chorób zapalnych
EP1847543A1 (fr) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines pour le traitement de maladies inflammatoires
CA2650290C (fr) * 2006-04-26 2015-11-17 Genentech, Inc. Composes pharmaceutiques
PT2024372E (pt) 2006-04-26 2010-09-16 Hoffmann La Roche Derivado de tieno[3,2-d]pirimidina útil como inibidor de pi3k
EP2046799B1 (fr) 2006-04-26 2017-07-19 Genentech, Inc. Composes inhibiteurs de phosphoinositide 3-kinase et compositions pharmaceutiques les contenant
TW200829594A (en) * 2006-12-07 2008-07-16 Piramed Ltd Phosphoinositide 3-kinase inhibitor compounds and methods of use
KR101460816B1 (ko) * 2006-12-07 2014-11-12 에프. 호프만-라 로슈 아게 포스포이노시타이드 3-키나제 억제제 화합물 및 그의 사용 방법
ES2399774T3 (es) 2007-09-24 2013-04-03 Genentech, Inc. Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
NZ585348A (en) 2007-10-19 2012-02-24 Boehringer Ingelheim Int Heterocycle-substituted piperazino-dihydrothienopyrimidines
PL2610258T3 (pl) * 2007-10-19 2015-02-27 Boehringer Ingelheim Int Podstawione piperydyno-dihydrotienopirymidyny
CA2702518A1 (fr) 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh Nouveaux derives de piperazino-dihydrothienopyrimidine
JP5348725B2 (ja) 2007-10-25 2013-11-20 ジェネンテック， インコーポレイテッド チエノピリミジン化合物の製造方法
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
KR101781654B1 (ko) 2009-03-12 2017-09-25 제넨테크, 인크. 조혈 악성종양의 치료를 위한 포스포이노시티드 ３-키나제 억제제 화합물 및 화학요법제의 조합물
SG182247A1 (en) * 2009-05-27 2012-08-30 Hoffmann La Roche Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
US8173650B2 (en) 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
PE20121816A1 (es) * 2009-10-12 2013-01-02 Hoffmann La Roche Combinaciones de un inhibidor de pi3k y un inhibidor de mek
WO2011130654A1 (fr) 2010-04-16 2011-10-20 Genentech, Inc. Foxo3a utilisée comme biomarqueur prédictif pour l'efficacité d'un inhibiteur de la voie des kinases p13k/akt
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
US9802954B2 (en) 2011-08-24 2017-10-31 Boehringer Ingelheim International Gmbh Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
US20130059866A1 (en) 2011-08-24 2013-03-07 Boehringer Ingelheim International Gmbh Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma
CA2901126C (fr) 2013-02-25 2022-01-25 Genentech, Inc. Procedes et compositions pour detecter et traiter un mutant d'akt resistant aux medicaments
MX2021003794A (es) * 2018-10-01 2021-09-08 Genzyme Corp Derivados de tieno[3,2-b]piridina como inhibidores de la udp glicosiltransferasa y metodos de uso.
GB202014736D0 (en) * 2020-09-18 2020-11-04 Imperial College Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
ES387553A1 (es) 1974-01-16
NL7101043A (fr) 1971-07-30
US3763156A (en) 1973-10-02
ES387554A1 (es) 1974-01-16
FR2081464A1 (fr) 1971-12-03
AU2468871A (en) 1972-07-27
FR2081464B1 (fr) 1975-04-18
GB1309182A (en) 1973-03-07
IL36079A0 (en) 1971-03-24
NO129205B (fr) 1974-03-11

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